Steven G Russell

US Patent:

20210106755, Apr 15, 2021

Filed:

Nov 16, 2020

Appl. No.:

17/099126

Inventors:

- Boston MA, US
Steven J. Russell - Lincoln MA, US

International Classification:

A61M 5/172
A61B 5/00
A61B 5/145

Abstract:

A glucose control system employs adaptation of a glucose target (set-point) control variable in controlling delivery of insulin to a subject to maintain euglycemia. The glucose target adapts based on trends in actual glucose level (e.g., measured blood glucose in the subject), and/or computed doses of a counter-regulatory agent such as glucagon. An adaptation region with upper and lower bounds for the glucose target may be imposed. Generally the disclosed techniques can provide for robust and safe glucose level control. Adaptation may be based on computed doses of a counter-regulatory agent whether or not such agent is actually delivered to the subject, and may be used for example to adjust operation in a bihormonal system during periods in which the counter-regulatory agent is not available for delivery.

US Patent:

20180220942, Aug 9, 2018

Filed:

Aug 8, 2016

Appl. No.:

15/748333

Inventors:

- Boston MA, US
Steven J. RUSSELL - Lincoln MA, US

International Classification:

A61B 5/145
A61B 5/00
A61M 5/172

Abstract:

A glucose control system employs adaptation of a glucose target (set-point) control variable in controlling delivery of insulin to a subject to maintain euglycemia. The glucose target adapts based on trends in actual glucose level (e.g., measured blood glucose in the subject), and/or computed doses of a counter-regulatory agent such as glucagon. An adaptation region with upper and lower bounds for the glucose target may be imposed. Generally the disclosed techniques can provide for robust and safe glucose level control. Adaptation may be based on computed doses of a counter-regulatory agent whether or not such agent is actually delivered to the subject, and may be used for example to adjust operation in a bihormonal system during periods in which the counter-regulatory agent is not available for delivery.