Steven D Sutton

US Patent:

6951882, Oct 4, 2005

Filed:

Dec 12, 2003

Appl. No.:

10/734800

Inventors:

Nicholas I Carruthers - Poway CA, US
Todd K. Jones - Solana Beach CA, US
Xiaobing Li - Flemington NJ, US
Timothy W. Lovenberg - San Diego CA, US
Laura C. McAtee - King of Prussia PA, US
Victor K. Phuong - San Diego CA, US
Dale A. Rudolph - San Diego CA, US
Steven W. Sutton - Carlsbad CA, US

Assignee:

Janssen Pharmaceutica N.V.

International Classification:

A61K031/357
C07D319/06

US Classification:

514452, 514314, 514444, 546173, 549 59, 549371

Abstract:

Urea-containing, substituted 4-phenyl-[1,3]-dioxanes, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, obesity or a sleep/wake disorder mediated by orexin-2 are described.

US Patent:

7618786, Nov 17, 2009

Filed:

Dec 11, 2003

Appl. No.:

10/537732

Inventors:

Steven W. Sutton - Carlsbad CA, US
Timothy W. Lovenberg - San Diego CA, US

Assignee:

Janssen Pharmaceutica N.V. - Beerse

International Classification:

G01N 33/53
G01N 33/566
G01N 33/567
C12N 15/85
C12N 5/08

US Classification:

435 71, 435 72, 435 721, 435 723, 435325, 435366, 435371, 436501

Abstract:

The present invention provides a new method for identifying modulators of human orexin-2 receptor without utilizing recombinantly produced nucleic acid molecules encoding human orexin receptor protein. This method combines and utilizes known methods and cell lines selected for their natural expression of orexin-2 receptors to carry out the methods of the present invention. Exemplary methods of the present invention utilize PFSK-1 cells to produce non-recombinant human orexin-2 receptor protein.

US Patent:

7893197, Feb 22, 2011

Filed:

Aug 25, 2005

Appl. No.:

11/660883

Inventors:

Pascal Bonaventure - San Diego CA, US
Chester Kuei - San Diego CA, US
Changlu Liu - San Diego CA, US
Timothy W. Lovenberg - San Diego CA, US
Steven W. Sutton - Carlsbad CA, US

Assignee:

Janssen Pharmaceutica N.V. - Beerse

International Classification:

A61K 38/00
C07K 14/64

US Classification:

530300, 530325, 530350

Abstract:

Chimeric polypeptides of relaxin-3, prepropolypeptides thereof, polynucleotides encoding such polypeptides, and associated expression vectors and host cells are described. The polypeptides may be used to prepare receptor-ligand complexes with GPCR135 or GPCR142, which may be used in assay methods.

US Patent:

8299028, Oct 30, 2012

Filed:

Jan 23, 2008

Appl. No.:

12/449137

Inventors:

Chester Kuei - San Diego CA, US
Changlu Liu - San Diego CA, US
Cindy M. Pudiak - Binghamton NY, US
Jonathan Edward Shelton - San Marcos CA, US
Steven W. Sutton - Carlsbad CA, US

Assignee:

Janssen Pharmaceutica NV - Beerse

International Classification:

A61K 38/22
C07K 14/64

US Classification:

514 127, 514 206, 514 213

Abstract:

The chimeric polypeptide R3(BΔ23-27)R/I5 is described, which is a high-affinity antagonist for GPCR1 35 and GPCR1 42 over LGR7.

US Patent:

20170173422, Jun 22, 2017

Filed:

Mar 1, 2017

Appl. No.:

15/446891

Inventors:

- Carlsbad CA, US
Matthew Myers - Carlsbad CA, US
Wee Joung Kim - Vista CA, US
Steven C. Sutton - Carlsbad CA, US
Larry Tang - Carlsbad CA, US
Denver Holt - Carlsbad CA, US

International Classification:

A63B 53/06
A63B 53/04
A63B 60/52
A63B 60/04

Abstract:

A golf club head comprising multiple means of adjusting the location of the center of gravity, and the bias, is disclosed herein. In a preferred embodiment, the golf club head comprises a non-metal medallion comprising a channel that is affixed to one of the crown and the sole, a slidable weight sized to fit within the channel, and a cover that attaches to the medallion and locks the slidable weight within the channel at a location selected by a user. The cover preferably includes at least one cutout so that the slidable weight is at least partially visible to the user when it is locked within the channel. The cover also includes additional cutouts that receive protrusions extending from the medallion to more securely attach the cover to the medallion.

US Patent:

20160129323, May 12, 2016

Filed:

Jan 14, 2016

Appl. No.:

14/995550

Inventors:

- Carlsbad CA, US
Denver Holt - Carlsbad CA, US
James A. Seluga - Carlsbad CA, US
Wee Joung Kim - Vista CA, US
Steven C. Sutton - Carlsbad CA, US

International Classification:

A63B 53/06
A63B 53/04

Abstract:

A golf club head comprising a slidable weight for adjusting the location of the golf club head center of gravity, as well as the golf club head bias, is disclosed herein. In particular, the golf club head, which may be a wood or iron-type head, comprises a pair of rails extending along at least one surface, such as a rear surface of an iron type head or a channel disposed in a wood-type head, and a slidable weight comprising a pair of grooves sized to receive the rails. In some embodiments, an applique or one or more clips are applied over or to the rails to prevent the weight from disengaging from the golf club head.

US Patent:

20160051869, Feb 25, 2016

Filed:

Nov 4, 2015

Appl. No.:

14/932171

Inventors:

- Carlsbad CA, US
Matthew Myers - Carlsbad CA, US
Wee Joung Kim - Vista CA, US
Steven C. Sutton - Carlsbad CA, US
Larry Tang - Carlsbad CA, US
Denver Holt - Carlsbad CA, US

International Classification:

A63B 53/04

Abstract:

A golf club head comprising multiple means of adjusting the location of the center of gravity, and the bias, is disclosed herein. In a preferred embodiment, the golf club head comprises a non-metal medallion comprising a channel that is affixed to one of the crown and the sole, a slidable weight sized to fit within the channel, and a cover that attaches to the medallion and locks the slidable weight within the channel at a location selected by a user. The cover preferably includes at least one cutout so that the slidable weight is at least partially visible to the user when it is locked within the channel. The cover also includes additional cutouts that receive protrusions extending from the medallion to more securely attach the cover to the medallion.