Steven D Weinstein

US Patent:

6350318, Feb 26, 2002

Filed:

Dec 17, 1998

Appl. No.:

09/213795

Inventors:

Kenneth J. Ruschak - Rochester NY
Daniel J. Suter - Penfield NY
Steven J. Weinstein - Fairport NY

Assignee:

Eastman Kodak Company - Rochester NY

International Classification:

B05C 500

US Classification:

118411, 118DIG 4

Abstract:

A versatile, multiple-slot, dual cavity, slide/extrusion hopper for assembling and coating a composite layer comprising a plurality of highly uniform, superposed compositions, and a method for determining the dimensions of the hopper are disclosed. The hopper is suitable for photographic applications and other applications requiring highly uniform layers. The hopper is versatile in that it can accommodate coating compositions that range from Newtonian to substantially shear thinning and in that fewer than the total number of elements may be supplied; the slide offsets between elements are suitable for both merging layers and for the top layer alone. The height of the secondary slot is preferably greater than the height of the primary slot. The method provides optimal cross-sectional shapes for the cavities. Versatility is achieved without greatly increasing the height or thickness of the elements.

US Patent:

7361350, Apr 22, 2008

Filed:

Feb 11, 2005

Appl. No.:

11/056730

Inventors:

Scott Mellis - New Rochelle NY, US
Neil Stahl - Carmel NY, US
Allen Radin - New York NY, US
Steven Weinstein - Hartsdale NY, US
Denise Calaprice - Nyack NY, US
Margaret Karow - Putnam Valley NY, US
Joanne Papadopoulos - LaGrangeville NY, US

Assignee:

Regeneron Pharmaceuticals, Inc. - Tarrytown NY

International Classification:

A61K 39/00
C07K 14/715

US Classification:

4241851, 4241921, 514 12, 530350

Abstract:

Methods of treating, inhibiting, or ameliorating arthritis, including rheumatoid arthritis, osteoarthritis, psoriatic arthritis, ankylosing spondylitis, or juvenile rheumatoid arthritis, in a human subject in need thereof, comprising administering to a subject in need a therapeutic amount of an interleukin 1 (IL-1) antagonist, wherein arthritis inhibited, or ameliorated. The IL-1 antagonist is an IL-1-specific fusion protein comprising an IL-1 binding portion of the extracellular domain of human II-1RAcP, an IL-1 binding portion of the extracellular domain of human IL-1RI, and a multimerizing component antagonist, preferably comprising a sequence selected from the group consisting of SEQ ID NO:4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, or a substantially identical sequence.

US Patent:

20060171948, Aug 3, 2006

Filed:

Feb 2, 2006

Appl. No.:

11/346007

Inventors:

Steven Weinstein - Hartsdale NY, US
Margaret Karow - Putnam Valley NY, US
Allen Radin - New York NY, US
William Roberts - Scarsdale NY, US
Li-Hsien Wang - Somers NY, US
Scott Mellis - New Rochelle NY, US

International Classification:

A61K 39/395
A61K 38/17

US Classification:

424145100, 514012000

Abstract:

Methods of reducing C-reactive protein (CRP) in a subject, comprising administering to the subject a therapeutic amount of an interleukin 1 (IL-1) antagonist, wherein CRP is reduced. The IL-1 antagonist is preferably an IL-1-binding fusion protein (IL-1 trap), preferably comprising SEQ ID NO:2.

US Patent:

20140056920, Feb 27, 2014

Filed:

Aug 20, 2013

Appl. No.:

13/971334

Inventors:

Marius ARDELEANU - White Plains NY, US
Namita A. GANDHI - New York NY, US
Neil GRAHAM - Croton-on-Hudson NY, US
Stephane C. KIRKESSELI - Paris, FR
Sudeep KUNDU - New York NY, US
Ross E. ROCKLIN - Basking Ridge NJ, US
Allen RADIN - New York NY, US
Steven P. WEINSTEIN - Hartsdale NY, US
Jennifer Davidson HAMILTON - Hopewell Junction NY, US
Jeffrey MING - Bridgewater NJ, US

Assignee:

REGENERON PHARMACEUTICALS, INC. - Tarrytown NY
SANOFI - Paris

International Classification:

C07K 16/28
A61K 39/395
A61K 45/06

US Classification:

4241731

Abstract:

The present invention provides methods for treating or preventing asthma and associated conditions in a patient. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody.

US Patent:

53106377, May 10, 1994

Filed:

Apr 14, 1992

Appl. No.:

7/868827

Inventors:

Mark R. Kurz - Rochester NY
Steven J. Weinstein - Fairport NY
Kenneth J. Ruschak - Rochester NY

Assignee:

Eastman Kodak Company - Rochester NY

International Classification:

G03C 146

US Classification:

430502

Abstract:

A method of reducing the tendency toward formation of ripple imperfections in the coating of multilayer photographic elements is disclosed. Coating compositions are prepared for upper, middle, and lower gelatin-containing layers of a layered mass. The middle layer has a gelatin concentration within three weight percent of each of the upper and lower layers and the upper, middle, and lower layers each have a viscosity that differs from a norm by no more than 15%. A laminar flow of a layered mass including the coating compositions is formed and then received as a layered coating on a moving support. A multilayer photographic element is also disclosed.

US Patent:

52060578, Apr 27, 1993

Filed:

Jan 10, 1992

Appl. No.:

7/819536

Inventors:

Douglas S. Finnicum - Webster NY
Kenneth J. Ruschak - Rochester NY
Steven J. Weinstein - Fairport NY

Assignee:

Eastman Kodak Company - Rochester NY

International Classification:

B05D 130

US Classification:

427420

Abstract:

In a curtain coating apparatus for the coating of photographic film and paper webs and the like, the line of impingement of the curtain on the moving web is controlled by providing a pressure controlled zone on one side of the flowing curtain. Small changes in the static air pressure in the zone cause the position of the curtain to move without disturbing the quality of the curtain. Wetted side walls of the pressure controlled zone can serve as edge guides for the curtain.

US Patent:

56837500, Nov 4, 1997

Filed:

Jul 30, 1996

Appl. No.:

8/688470

Inventors:

Joseph W. Hoff - Fairport NY
Douglas S. Finnicum - Webster NY
Steven J. Weinstein - Fairport NY

Assignee:

Eastman Kodak Company - Rochester NY

International Classification:

B05D 130
B05D 500

US Classification:

427261

Abstract:

A method of coating moveable supports at high speeds comprises moving the support along a path through a coating zone, forming two or more layers of coating liquids including an actual top coat layer to form a liquid composition (with a slide hopper coating a plurality of outlets for coating liquids) and applying a starting top most layer of coating liquid, which layer has a lower viscosity than that of the actual top coat layer, to the liquid coating composition either through the first outlet of the hopper or through an x-hopper located between the first outlet and coating zone, applying the coating composition and starting top most layer, and terminating the application of the starting top most layer when the coating operation is at steady state. Apparatus for carrying out this method is also described.

US Patent:

53065271, Apr 26, 1994

Filed:

Apr 14, 1992

Appl. No.:

7/868829

Inventors:

Mark R. Kurz - Rochester NY
Steven J. Weinstein - Fairport NY
Kenneth J. Ruschak - Rochester NY

Assignee:

Eastman Kodak Company - Rochester NY

International Classification:

B05D 130

US Classification:

427420

Abstract:

A method for reducing the tendency toward the formation of ripple imperfections in the coating of a plurality of layers of liquid photographic compositions or moving webs is disclosed. Conditions for coating the compositions are determined according to a given formula to keep the ripple value below 35. The coating compositions are formed into a laminar flow of a plurality of distinct layers including the photographic compositions as upper, middle, and lower layers. The flowing plurality of layers is then received as a layered mass on a moving web. A method for predicting the tendency toward the formation of ripple imperfections in the coating of a multilayer photographic element is also disclosed.