David Myung - Santa Clara CA, US Lampros Kourtis - Stanford CA, US Laura Hartmann - San Francisco CA, US Curtis W. Frank - Cupertino CA, US Stuart B. Goodman - Los Altos CA, US Dennis R. Carter - Stanford CA, US
International Classification:
A61F 2/08
US Classification:
623 1412, 424486, 424423, 424426
Abstract:
An arthroplasty device is provided having an interpenetrating polymer network (IPN) hydrogel that is strain-hardened by swelling and adapted to be held in place in a joint by conforming to a bone geometry. The strain-hardened IPN hydrogel is based on two different networks: (1) a non-silicone network of preformed hydrophilic non-ionic telechelic macromonomers chemically cross-linked by polymerization of its end-groups, and (2) a non-silicone network of ionizable monomers. The second network was polymerized and chemically cross-linked in the presence of the first network and has formed physical cross-links with the first network. Within the IPN, the degree of chemical cross-linking in the second network is less than in the first network. An aqueous salt solution (neutral pH) is used to ionize and swell the second network. The swelling of the second network is constrained by the first network resulting in an increase in effective physical cross-links within the IPN.
Methods For The Control Of Macrophage-Associated Inflammation
Jeremy Pearl - Stanford CA, US Ting Ma - Stanford CA, US William H. Robinson - Palo Alto CA, US R. Lane Smith - Stanford CA, US Stuart B. Goodman - Stanford CA, US
International Classification:
A61K 38/02 A61P 29/00
US Classification:
514 2
Abstract:
Particle induced inflammatory diseases are treated by administration of an effective dose of an inhibitor of MyD88 adaptor protein.
David Myung - Santa Clara CA, US Lampros Kourtis - Stanford CA, US Laura Hartmann - San Francisco CA, US Curtis W. Frank - Cupertino CA, US Stuart B. Goodman - Los Altos CA, US Dennis R. Carter - Stanford CA, US
International Classification:
A61F 2/02
US Classification:
623 1412
Abstract:
An arthroplasty device is provided having an interpenetrating polymer network (IPN) hydrogel that is strain-hardened by swelling and adapted to be held in place in a joint by conforming to a bone geometry. The strain-hardened IPN hydrogel is based on two different networks: (1) a non-silicone network of preformed hydrophilic non-ionic telechelic macromonomers chemically cross-linked by polymerization of its end-groups, and (2) a non-silicone network of ionizable monomers. The second network was polymerized and chemically cross-linked in the presence of the first network and has formed physical cross-links with the first network. Within the IPN, the degree of chemical cross-linking in the second network is less than in the first network. An aqueous salt solution (neutral pH) is used to ionize and swell the second network. The swelling of the second network is constrained by the first network resulting in an increase in effective physical cross-links within the IPN.
Unbalanced Prosthetic Device For Providing Side-Dependent Twisting-Rotational Axial-Loading Coupling
Fu-Kuo Chang - Stanford CA Hasan Yildiz - No. 19 G. O. P. Istanbul, TR Stuart B. Goodman - Los Altos CA
International Classification:
A61F 236
US Classification:
623 2334
Abstract:
The present invention discloses a side-dependent prosthetic device. The side-dependent prosthetic device is a composite prosthetic device with a longitudinal direction. The composite prosthetic device includes a plurality of plies wherein each ply being composed of a plurality of reinforced fibers aligned in a ply orientational angle. theta. i relative to the longitudinal direction of the prosthetic device, where i=1,2,3,. . . ,N and N being the number of the plies. The plurality of plies are laminated together for forming the prosthetic device wherein the ply orientational angles being arranged such that. theta. 1+. theta. 2+. theta. 3+. . . +. theta. sub. N -0 thus forming an unbalanced composite prosthetic device. In another preferred embodiment, the ply orientational angles. theta. i forming a sequence which is represented by ((. theta. sup. 1 /. theta. sup. 2). sub. s). sub.
Customized Load-Bearing And Bioactive Functionally-Graded Implant For Treatment Of Osteonecrosis
- Stanford CA, US Stuart B. Goodman - Los Altos CA, US Yaser Shanjani - Milpitas CA, US Chi-Chun Pan - Stanford CA, US
International Classification:
A61F 2/28
Abstract:
An engineered medical device for treatment of osteonecrosis is provided where the size, porosity and ceramic content of the device can be personalized based on an individual patient's anatomical and physiological condition. The device distinguishes different segments mimicking anatomically-relevant cortical and cancellous segments, in which the cortical segments of the device can sustain mechanical loading, and the cancellous segment of the device can promote bone ingrowth, osteogenesis and angiogenesis.
Systemic Targeting Of Inflammatory Sites And Enhanced Immunomodulatory Function By Introducing The Chimeric Antigen Receptor (Car) Into Mesenchymal Stem Cells For Inflammatory And Autoimmune Diseases
Mesenchymal stromal cells are engineered to express a chimeric antigen receptor (CAR), that specifically binds a marker of activated myeloid cells, including without limitation folate receptor beta; and are administered to an individual for treatment of inflammation at sites characterized by the presence of activated myeloid cells.
Methods And Compositions For Inducible Production Of Anti-Inflammatory Cytokines
Provided are compositions and methods for production of anti-inflammatory cytokines, growth factors, or chemokines. Provided are nucleic acids (e.g., expression vectors) that include an NFκB inflammation response element operably linked to a nucleotide sequence encoding an anti-inflammatory cytokine (e.g., IL-4). In some cases, the nucleic acid is an expression vector selected from: a linear expression vector, a circular expression vector, a plasmid, and a viral expression vector. Also provided are cells (e.g., mesenchymal stem cells—MSCs) comprising a nucleic acid that includes an NFB inflammation response element operably linked to a nucleotide sequence encoding an anti-inflammatory cytokine. In some cases, the nucleic acid is integrated into the cell's genome. Also provided are methods for treating an individual having an inflammation-associated ailment, which can include administering an MSC to the individual, where the MSC includes an NFB inflammation response element operably linked to a nucleotide sequence encoding an anti-inflammatory cytokine.
- Stanford CA, US Lampros KOURTIS - San Francisco CA, US Laura HARTMANN - Berlin, DE Curtis W. FRANK - Cupertino CA, US Stuart B. GOODMAN - Los Altos CA, US Dennis R. CARTER - Stanford CA, US
Assignee:
The Board of Trustees of The Leland Stanford Junior University - Stanford CA
An arthroplasty device is provided having an interpenetrating polymer network (IPN) hydrogel that is strain-hardened by swelling and adapted to be held in place in a joint by conforming to a bone geometry. The strain-hardened IPN hydrogel is based on two different networks: (1) a non-silicone network of preformed hydrophilic non-ionic telechelic macromonomers chemically cross-linked by polymerization of its end-groups, and (2) a non-silicone network of ionizable monomers. The second network was polymerized and chemically cross-linked in the presence of the first network and has formed physical cross-links with the first network. Within the IPN, the degree of chemical cross-linking in the second network is less than in the first network. An aqueous salt solution (neutral pH) is used to ionize and swell the second network. The swelling of the second network is constrained by the first network resulting in an increase in effective physical cross-links within the IPN.
Corporate Law Business Law Securities Securities Offerings Securities Regulation Securities Disclosure Corporate Control Contests Insurance Public Companies Advertising Tax Advertising
Dr. Goodman graduated from the University of Arizona College of Medicine at Tucson in 1979. He works in Billings, MT and specializes in Surgery , Neurological. Dr. Goodman is affiliated with Saint Vincent Healthcare.
Dr. Goodman graduated from the University of the East - Ramon Magsaysay Memorial Medical Center, Quezon City, Philippines in 1977. He works in Frederick, MD and specializes in Neurology. Dr. Goodman is affiliated with Frederick Memorial Hospital and Holy Cross Hospital.
Stanford Health Outpatient Center 450 Broadway St, Redwood City, CA 94063 6507235643 (phone), 6507213422 (fax)
Education:
Medical School Univ of Toronto, Fac of Med, Toronto, Ont, Canada Graduated: 1978
Procedures:
Arthrocentesis Hip Replacement Joint Arthroscopy Knee Arthroscopy Knee Replacement Shoulder Surgery Hip/Femur Fractures and Dislocations Wound Care
Conditions:
Osteoarthritis Fractures, Dislocations, Derangement, and Sprains Internal Derangement of Knee Cartilage Internal Derangement of Knee Ligaments Rheumatoid Arthritis
Languages:
English Spanish
Description:
Dr. Goodman graduated from the Univ of Toronto, Fac of Med, Toronto, Ont, Canada in 1978. He works in Redwood City, CA and specializes in Orthopaedic Surgery. Dr. Goodman is affiliated with Stanford Hospital.
300 Pasteur Dr, Stanford, CA 94305 900 Blake Wilbur Dr, Palo Alto, CA 94304 450 Broadway St, Redwood City, CA 94063
Education:
Lund University - Doctor of Philosophy University of Toronto, Faculty of Medicine - Doctor of Medicine University Health Network-Toronto General Hospital - Residency - Orthopaedic Surgery
Board certifications:
American Board of Orthopaedic Surgery Certification in Orthopaedic Surgery
Youtube
Total Joint Replacement at Stanford Hospital,...
Stuart Goodman, MD, PhD, Orthopaedic Surgeon, discusses risk factors a...
Duration:
3m 13s
Health Connection: Deep Brain Stimulation Wit...
People suffering with Essential Tremor have difficulty doing daily tas...
Duration:
1m
Stuart Goodman - Let's face it!
Every face is different and unique. Face Reading is a unique skill, wh...
Duration:
1m 4s
John Prine steve goodman Souvenirs
You gotta love John Prine and Steve goodman! Second track is Steve Goo...
Duration:
7m 33s
Stuart Goodman Live at The Dark Shadows Weeke...
Stuart Goodman Live at The Dark Shadows Weekend Gathering 2012.
Hibbard Elementary School Chicago IL 1948-1955, East Prairie Elementary School Skokie IL 1955-1957
Community:
James Harris, Marilyn Holtz, Roger Powell, Andi Irgang, Carl Martin, Gloria Krone, Paula Meyers, Michael Cavanaugh, Renee Haskell, Elayne Swider, Ted Masters
s co-founder, said she wanted the memorial to become a place of gathering for bereaved families. The first anniversary of the death of her father, Stuart Goodman, is Friday, and this week she met for the first time the other co-founder of the group, Matt Fowler, who also lost his father last year.
Date: Apr 01, 2021
Category: More news
Source: Google
Family, friends defend tennis umpire accused of killing husband
"Lois was always solicitous of Alan's needs as his medical condition deteriorated," Jay, Evelyn and Stuart Goodman wrote. "A few years ago, Alan was in an auto accident; Lois was in Ojai, umpiring a tennis tournament .... She immediately wanted to make arrangements to come ho