Stuart J Kahn

US Patent:

20100190798, Jul 29, 2010

Filed:

Jan 23, 2010

Appl. No.:

12/692593

Inventors:

John A. Zebala - Sammamish WA, US
Dean Y. Maeda - Seattle WA, US
Joel R. Morgan - Kent WA, US
Stuart J. Kahn - Seattle WA, US

International Classification:

A61K 31/519
C07D 475/08
A61P 19/02
A61P 17/00
A61P 1/00
A61P 35/02
A61P 35/00

US Classification:

514249, 544260

Abstract:

There is disclosed a pharmaceutical composition comprising racemic aminopterin or pharmaceutically acceptable salts thereof. There is further disclosed a method to treat a disorder in a patient comprising administering a therapeutically effective amount of racemic aminopterin or pharmaceutically acceptable salts of racemic aminopterin. More particularly, there is disclosed a method for treating disorders modulated by at least dihydrofolate reductase activity, such as cancers and inflammatory disorders, wherein the method comprises administering to a patient in need thereof a therapeutically effective amount of racemic aminopterin or a pharmaceutically acceptable salt thereof.

Address:

7013 56 Ave NE, Seattle, WA 98115

Phone:

2065240214

VIN:

JTDKB20U273291675

Make:

TOYOTA

Model:

PRIUS

Year:

2007