Suknan S Chang

US Patent:

7608465, Oct 27, 2009

Filed:

Sep 13, 2002

Appl. No.:

10/243145

Inventors:

Michael I. Watkins - Vacaville CA, US
Suknan S. Chang - Oakland CA, US
Renato B. Del Rosario - Benicia CA, US
Patricia A. Miranda - Novato CA, US
Timothy D. Knight - Benicia CA, US
Richard B. Edwards - Cold Spring NY, US

Assignee:

Bio-Rad Laboratories, Inc. - Hercules CA

International Classification:

G01N 33/53

US Classification:

436500, 435 71, 435 794, 435176, 4352872, 435973, 436518, 436526, 436172, 422 73, 422 8208, 422101

Abstract:

Immunological assays for several biological markers for thyroid disorders in a biological sample are performed in a single test with a combination of sandwich-type, sequential competitive, and serological assays by the use of particles classified into groups that are distinguishable by flow cytometry, one group for the assay of each marker. Each group of particles is coated with a different immunological binding member, and coating densities, co-coating materials, and special buffer solutions are used to adjust for differences in the sensitivities and dynamic ranges of each of the markers in the typical sample.

US Patent:

20070178604, Aug 2, 2007

Filed:

Mar 22, 2007

Appl. No.:

11/726856

Inventors:

Michael Watkins - Vacaville CA, US
Suknan Chang - Oakland CA, US
Renato Del Rosario - Benecia CA, US
Patricia Miranda - Novato CA, US
Timothy Knight - Benecia CA, US
Richard Edwards - Cold Spring NY, US

Assignee:

Bio-Rad Laboratories, Inc. - Hercules CA

International Classification:

G01N 33/53

US Classification:

436500000

Abstract:

Immunological assays for several biological markers for thyroid disorders in a biological sample are performed in a single test with a combination of sandwich-type, sequential competitive, and serological assays by the use of particles classified into groups that are distinguishable by flow cytometry, one group for the assay of each marker. Each group of particles is coated with a different immunological binding member, and coating densities, co-coating materials, and special buffer solutions are used to adjust for differences in the sensitivities and dynamic ranges of each of the markers in the typical sample.

US Patent:

7271009, Sep 18, 2007

Filed:

Apr 13, 2000

Appl. No.:

09/548883

Inventors:

Michael I. Watkins - Vacaville CA, US
Suknan S. Chang - Oakland CA, US
Renato B. Del Rosario - Benicia CA, US
Patricia A. Miranda - Novato CA, US
Timothy D. Knight - Benicia CA, US
Richard B. Edwards - Cold Spring NY, US

Assignee:

Bio-Rad Laboratories, Inc. - Hercules CA

International Classification:

G01N 33/553

US Classification:

436526, 436518, 436538, 436540, 436546, 436 10, 436172, 436177, 435 71, 435 794, 4352872, 435973, 422 681, 422 8207, 422101

Abstract:

Immunological assays for several biological markers for thyroid disorders in a biological sample are performed in a single test with a combination of sandwich-type, sequential competitive, and serological assays by the use of particles classified into groups that are distinguishable by flow cytometry, one group for the assay of each marker. Each group of particles is coated with a different immunological binding member, and coating densities, co-coating materials, and special buffer solutions are used to adjust for differences in the sensitivities and dynamic ranges of each of the markers in the typical sample.