Surinder Kaur

US Patent:

8541178, Sep 24, 2013

Filed:

May 12, 2009

Appl. No.:

12/464250

Inventors:

Surinder Kaur - Lafayette CA, US
Ola Saad - Walnut Creek CA, US
Keyang Xu - Belmont CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

G01N 33/53
A61K 39/395

US Classification:

435 71, 424 92, 4241781, 4241811, 530413, 5303917, 5303919

Abstract:

Methods to detect, characterize, and quantitate biological samples after administration of antibody conjugates, antibody-drug conjugates of Formula I, antibodies, and fragments and metabolites thereof, by immunoaffinity bead separation, chromatography, and mass spectrometry are disclosed;Ab-(L-D)  I.

US Patent:

20120315645, Dec 13, 2012

Filed:

May 11, 2012

Appl. No.:

13/469332

Inventors:

Surinder Kaur - Lafayette CA, US
Ola Saad - Walnut Creek CA, US
Keyang Xu - Belmont CA, US

International Classification:

G01N 27/62

US Classification:

435 71, 435 23

Abstract:

Methods are disclosed to detect, characterize, measure, and quantitate human and humanized antibodies, and their conjugates, present in pre-clinical animal biological samples, including plasma/serum and tissue samples.

US Patent:

58917420, Apr 6, 1999

Filed:

Jan 19, 1995

Appl. No.:

8/375979

Inventors:

Gavin D. Dollinger - San Francisco CA
Verena D. Huebner - Benicia CA
Surinder Kaur - Lafayette CA

Assignee:

Chiron Corporation - Emeryville CA

International Classification:

G01N 33537

US Classification:

436538

Abstract:

Compounds are quickly selected from a combinatorial library by contacting the library with a target (e. g. , receptor), separating non-binding compounds from compound-target complexes, and analyzing the complexes or eluted compound by mass spectroscopy. SAR information is obtained by performing this selection at two or more different ratios of compound to target.

US Patent:

20210011000, Jan 14, 2021

Filed:

May 26, 2020

Appl. No.:

16/883152

Inventors:

- South San Francisco CA, US
Surinder Kaur - Lafayette CA, US
Dian Su - Redwood City CA, US
Keyang Xu - Belmont CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

G01N 33/50
G01N 33/68
C12Q 1/37
A61K 38/02
A61K 39/395
G01N 33/53

Abstract:

Methods to rapidly and accurately detect, characterize, measure, and quantify site-specific antibody drug conjugates, that may be present in pre-clinical animal biological samples, or human biological samples, including plasma/serum and tissue samples.

US Patent:

20170370906, Dec 28, 2017

Filed:

May 26, 2017

Appl. No.:

15/606304

Inventors:

- South San Francisco CA, US
Surinder Kaur - Lafayette CA, US
Dian Su - Redwood City CA, US
Keyang Xu - Belmont CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

G01N 33/50
A61K 39/395
G01N 33/53
A61K 38/02
C07K 14/00

Abstract:

Methods to rapidly and accurately detect, characterize, measure, and quantify site-specific antibody drug conjugates, that may be present in pre-clinical animal biological samples, or human biological samples, including plasma/serum and tissue samples.