Susan M Mcknight

US Patent:

20070041972, Feb 22, 2007

Filed:

May 28, 2004

Appl. No.:

10/559085

Inventors:

Russell Rother - Prospect CT, US
Dayang Wu - Cheshire CT, US
Stephen Squinto - Bethany CT, US
Mark Evans - Radnor PA, US
Susan McKnight - Old Lyme CT, US

Assignee:

ALEXION PHARMACEUTICALS, INC. - CHESHIRE CT

International Classification:

A61K 39/395
C07H 21/04
C12P 21/06
C07K 16/24
C07K 16/46
C12N 5/06

US Classification:

424145100, 424178100, 530388230, 530391100, 435069100, 435326000, 435320100, 536023530

Abstract:

Antibodies and/or fusion proteins contain a region that includes an IgG2-derived portion IgG4-derived portion.

US Patent:

20070292416, Dec 20, 2007

Filed:

May 28, 2004

Appl. No.:

10/559543

Inventors:

Russell Rother - Prospect CT, US
Susan McKnight - Old Lyme CT, US
Dayang Wu - Cheshire CT, US
Francis Carr - Aberdeenshire, GB
Anita Hamilton - Aberdeen, GB

Assignee:

Alexion Pharmaceuticals, Inc. - Cheshire CT

International Classification:

A61K 39/395
A61P 37/00
C07H 21/02
C07K 16/00
C12N 15/00
C12P 21/00

US Classification:

424131100, 435320100, 435069600, 530387100, 536023100

Abstract:

Antibodies or functional antibody fragments that recognize or interfere with the production of a component of the CD3 antigen complex are de-immunized.

US Patent:

20090145020, Jun 11, 2009

Filed:

Dec 4, 2008

Appl. No.:

12/327856

Inventors:

Susan McKnight - West Hartford CT, US

International Classification:

A01M 1/10
A01N 25/00

US Classification:

43123, 424 84, 43121

Abstract:

A climb-up pitfall trap for attracting and capturing bed bugs and the like comprises a rough exterior surface, a precipice, a smooth interior surface and sensory lures. The sensory lures include heat, carbon dioxide and/or a lure composition. The lure composition comprises a combination of (a) L-lactic acid, and (b) a fatty acid from the group consisting of (1) propionic acid, (2) butyric acid, and (3) valeric acid. The lure composition may also comprise (c) octenol. A method for attracting and capturing bed bugs and the like uses the climb-up pitfall trap in a bed bug infested environment.

US Patent:

20090282728, Nov 19, 2009

Filed:

May 5, 2009

Appl. No.:

12/387645

Inventors:

Susan McKnight - West Hartford CT, US
Changlu Wang - West Lafayette IN, US

International Classification:

A01M 1/00
A01M 1/24

US Classification:

43109, 43107, 43123

Abstract:

An intercepting device (e.g. a furniture coaster device) is placed under furniture (bed, sofa, chair. etc.), other climbable object, or the floor adjacent an object to intercept crawling arthropods and other crawling pests. The intercepting device can be used to monitor the presence of crawling arthropods and other crawling pests (such as bed bugs, ants, cockroaches, beetles, spiders, etc.), reduce pest numbers, and monitor efficacy of pest control procedures. The intercepting device includes pitfall trap surfaces that form multiple pitfall traps.

US Patent:

20110203159, Aug 25, 2011

Filed:

Apr 28, 2011

Appl. No.:

13/096468

Inventors:

Susan McKnight - West Hartford CT, US

Assignee:

Susan McKnight, Inc. - Memphis TN

International Classification:

A01M 1/10
A01N 25/00

US Classification:

43123, 424 84

Abstract:

A method for attracting bed bugs includes placing a climb-up pitfall trap apparatus that includes a chemical lure composition. The lure composition includes a combination of (a) L-lactic acid, and (b) at least one fatty acid or salt selected from the group consisting of (1) propionic acid, (2) butyric acid, and (3) valeric acid, and (c) 1-octen-3-ol, and (d) a suitable ketone, and (e) a suitable aliphatic sulfide. The trap may also include in conjunction with the lure composition a carbon dioxide source and/or a heat source to compose a lure arrangement.

US Patent:

20110225873, Sep 22, 2011

Filed:

May 31, 2011

Appl. No.:

13/134150

Inventors:

Susan McKnight - West Hartford CT, US
Changlu Wang - West Lafayette IN, US

International Classification:

A01M 1/10

US Classification:

43123

Abstract:

An intercepting device (e.g. a furniture coaster device) is placed under furniture (bed, sofa, chair. etc.), other climable object, or the floor adjacent an object to intercept crawling arthropods and other crawling pests. The intercepting device can be used to monitor the presence of crawling arthropods and other crawling pests (such as bed bugs, ants, cockroaches, beetles, spiders, etc.), reduce pest numbers, and monitor efficacy of pest control procedures. The intercepting device includes pitfall trap surfaces that form multiple pitfall traps.

US Patent:

20130172534, Jul 4, 2013

Filed:

Feb 20, 2013

Appl. No.:

13/771911

Inventors:

ALEXION PHARMACEUTICALS, INC. - Cheshire CT, US
Susan Faas McKnight - Old Lyme CT, US
Jeremy P. Springhorn - Guilford CT, US
Dayang Wu - Cheshire CT, US

Assignee:

ALEXION PHARMACEUTICALS, INC. - Cheshire CT

International Classification:

C07K 16/28

US Classification:

5303873, 5303879

Abstract:

This application provides methods and compositions for modulating and/or depleting CD200 positive cells.

US Patent:

20130202602, Aug 8, 2013

Filed:

Jan 11, 2011

Appl. No.:

13/521671

Inventors:

Susan Faas McKnight - Old Lyme CT, US
Roxanne Cofiell - Glastonbury CT, US
Yan Yan - Cheshire CT, US

Assignee:

Alexion Pharmaceuticals ,Inc. - Cheshire CT

International Classification:

A61K 39/395
G01N 33/68
G01N 33/50

US Classification:

4241351, 4241391, 4241331, 435 39, 435 724

Abstract:

The present disclosure relates to anti-CD200 antibodies (e.g., variant anti-CD200 antibodies having decreased or no effector function) and to biomarkers for use in a variety of diagnostic and therapeutic methods, e.g., determining whether a human has been administered one or more of the antibodies at a dose sufficient to induce a desired immunomodulatory effect in the human and/or selecting an appropriate dosing schedule for a patient.