Yanwei Wang - Woodinville WA, US Fuxing Yang - Woodinville WA, US Susannah Helen Bloch - Seattle WA, US Stephen Dudycha - Bothell WA, US Gerald McMorrow - Redmond WA, US
Assignee:
Verathon Inc. - Bothell WA
International Classification:
A61B 8/00
US Classification:
600437, 600439, 600447, 600441, 600443
Abstract:
Systems, methods, and devices for image clarity of ultrasound-based images are described wherein motion sections are compensated with the still sections of the region of interest. Velocity map analysis of regions-of-interest is determined to compensate for instrument motion from motions attributable to structures within the region of interest. Methods include image processing algorithms applied to collected echogenic data sets and the dispensers that use apply air-expunged sonic coupling mediums.
Ultrasonic Concentration Of Drug Delivery Capsules
Paul Dayton - Davis CA, US Katherine Ferrara - Davis CA, US Michaelann Shortencarier - Sacramento CA, US Susannah Bloch - Davis CA, US
Assignee:
The Regents of the University of California, A California corporation - Oakland CA
International Classification:
A61K038/00 A61N001/30 A61K009/14
US Classification:
424489000, 514002000, 604020000
Abstract:
Methods, compositions and apparatus for localized delivery of compounds are provided. In certain embodiments, radiation force is used to direct carriers to a target site, and additional radiation is used to fragment the localized carriers, releasing associate compounds. Ultrasound radiation is preferred as the source for radiation force and for fragmentation. Also encompassed are embodiments in which targeting and fragmentations are combined with imaging of the treatment site. Alternate embodiments are disclosed in which compounds are locally delivered without use of carriers.
Methods, compositions, and apparatus for localized delivery of compounds are provided. In certain embodiments, acoustic streaming force is used to direct carrier particles to a target site, mediate particle internalization, and release associate compounds. Ultrasound radiation is preferred as the source for the acoustic streaming force. Also encompassed are embodiments in which targeting and membrane permeability enhancement are combined with imaging of the treatment site.
3D Ultrasound-Based Instrument For Non-Invasive Measurement Of Amniotic Fluid Volume
Vikram Chalana - Mill Creek WA, US Yanwei Wang - Woodinville WA, US Fuxing Yang - Woodinville WA, US Susannah Helen Bloch - Seattle WA, US Stephen Dudycha - Bothell WA, US Gerald McMorrow - Redmond WA, US
International Classification:
A61B 8/00
US Classification:
600447
Abstract:
A hand-held 3D ultrasound instrument is disclosed which is used to non-invasively and automatically measure amniotic fluid volume in the uterus requiring a minimum of operator intervention. Using a 2D image-processing algorithm, the instrument gives automatic feedback to the user about where to acquire the 3D image set. The user acquires one or more 3D data sets covering all of the amniotic fluid in the uterus and this data is then processed using an optimized 3D algorithm to output the total amniotic fluid volume corrected for any fetal head brain volume contributions.