Celera - Alameda, CA since Dec 2010
Manager, Manufacturing Technical Support
Celera 2005 - 2010
Staff Scientist
Applied Biosystems 1999 - 2005
Senior Scientist
Tm Technologies - Woburn, MA 1993 - 1998
Senior Scientist
Education:
University of Illinois at Chicago 1987 - 1993
Doctor of Philosophy (Ph.D.), Chemistry
University of the Philippines
Bachelor of Science (BS), Agricultural Chemistry
Skills:
Biochemistry Dna Chemistry Molecular Biology Gmp Test Method Validation Root Cause Analysis High Throughput Assay Development Manufacturing Operations Management R&D Organic Chemistry Test Methodologies Protein Chemistry Technical Support Biotechnology Design of Experiments
Languages:
English
Us Patents
Concatameric Ligation Products: Compositions, Methods And Kits For Same
Caifu Chen - Palo Alto CA, US Kevin Hennessy - San Mateo CA, US Kai Lao - Pleasanton CA, US Teodoro Paner - Dublin CA, US Vinod Mirchandani - San Ramon CA, US
Assignee:
Applera Corporation - Foster City CA
International Classification:
C12Q 1/68 C12P 19/34
US Classification:
435006000, 435091200
Abstract:
The present teachings relate to methods, compositions, and kits for detecting one or more target polynucleotide sequences in a sample, and methods compositions and kits for forming concatameric ligation products. In some embodiments of the present teachings, oligonucleotides are hybridized to complementary target polynucleotides and are ligated together to form a concatameric ligation product. In some embodiments of the present teachings, the concatameric ligation product can be amplified, and the identity and quantity of the target polynucleotides determined based on sequence introduced in the ligation reaction. Some embodiments of the present teachings provide methods for removing unligated probes from the reaction mixture. Some embodiments of the present teachings provide for highly multiplexed detection, identification, and quantification of a plurality of target polynucleotides using a variety of analytical procedures.
Concatameric Ligation Products: Compositions, Methods And Kits For Same
Caifu Chen - Palo Alto CA, US Kevin Hennessy - San Mateo CA, US Kai Lao - Pleasanton CA, US Teodoro Paner - Dublin CA, US Vinod Mirchandani - San Ramon CA, US
Assignee:
APPLERA CORPORATION - Foster City CA
International Classification:
C12Q 1/68 C07H 21/04
US Classification:
435006000, 536024300
Abstract:
The present teachings relate to methods, compositions, and kits for detecting one or more target polynucleotide sequences in a sample, and methods compositions and kits for forming concatameric ligation products. In some embodiments of the present teachings, oligonucleotides are hybridized to complementary target polynucleotides and are ligated together to form a concatameric ligation product. In some embodiments of the present teachings, the concatameric ligation product can be amplified, and the identity and quantity of the target polynucleotides determined based on sequence introduced in the ligation reaction. Some embodiments of the present teachings provide methods for removing unligated probes from the reaction mixture. Some embodiments of the present teachings provide for highly multiplexed detection, identification, and quantification of a plurality of target polynucleotides using a variety of analytical procedures.
Concatameric Ligation Products: Compositions, Methods And Kits For Same
Caifu Chen - Palo Alto CA, US Kevin Hennessy - San Mateo CA, US Kai Lao - Pleasanton CA, US Teodoro Paner - Dublin CA, US Vinod Mirchandani - San Ramon CA, US
Assignee:
APPLERA CORPORATION - Foster City CA
International Classification:
C12Q 1/68 C12P 19/34
US Classification:
435006000, 435091200
Abstract:
The present teachings relate to methods, compositions, and kits for detecting one or more target polynucleotide sequences in a sample, and methods compositions and kits for forming concatameric ligation products. In some embodiments of the present teachings, oligonucleotides are hybridized to complementary target polynucleotides and are ligated together to form a concatameric ligation product. In some embodiments of the present teachings, the concatameric ligation product can be amplified, and the identity and quantity of the target polynucleotides determined based on sequence introduced in the ligation reaction. Some embodiments of the present teachings provide methods for removing unligated probes from the reaction mixture. Some embodiments of the present teachings provide for highly multiplexed detection, identification, and quantification of a plurality of target polynucleotides using a variety of analytical procedures.
Concatameric Ligation Products: Compositions Methods And Kits For Same
Caifu CHEN - Palo Alto CA, US Kevin Hennessy - San Mateo CA, US Kai Qin Lao - Pleasanton CA, US Teodoro Paner - Dublin CA, US Vinod Mirchandani - San Ramon CA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
C12Q 1/68 C07H 21/04
US Classification:
435 6, 536 231, 536 2433
Abstract:
The present teachings relate to methods, compositions, and kits for detecting one or more target polynucleotide sequences in a sample, and methods compositions and kits for forming concatameric ligation products. In some embodiments of the present teachings, oligonucleotides are hybridized to complementary target polynucleotides and are ligated together to form a concatameric ligation product. In some embodiments of the present teachings, the concatameric ligation product can be amplified, and the identity and quantity of the target polynucleotides determined based on sequence introduced in the ligation reaction. Some embodiments of the present teachings provide methods for removing unligated probes from the reaction mixture. Some embodiments of the present teachings provide for highly multiplexed detection, identification, and quantification of a plurality of target polynucleotides using a variety of analytical procedures.
Concatameric Ligation Products: Compositions Methods And Kits For Same
Caifu Chen - Palo Alto CA, US Kevin Hennessy - San Mateo CA, US Kai Qin Lao - Pleasanton CA, US Teodoro Paner - Dublin CA, US Vinod Mirchandani - San Ramon CA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
C12Q 1/68 C07H 21/04
US Classification:
435 611, 536 231, 536 2433
Abstract:
The present teachings relate to methods, compositions, and kits for detecting one or more target polynucleotide sequences in a sample, and methods compositions and kits for forming concatameric ligation products. In some embodiments of the present teachings, oligonucleotides are hybridized to complementary target polynucleotides and are ligated together to form a concatameric ligation product. In some embodiments of the present teachings, the concatameric ligation product can be amplified, and the identity and quantity of the target polynucleotides determined based on sequence introduced in the ligation reaction. Some embodiments of the present teachings provide methods for removing unligated probes from the reaction mixture. Some embodiments of the present teachings provide for highly multiplexed detection, identification, and quantification of a plurality of target polynucleotides using a variety of analytical procedures.
Concatameric Ligation Products: Compositions Methods And Kits For Same
- Carlsbad CA, US Kevin HENNESSY - San Mateo CA, US Kai LAO - Pleasanton CA, US Teodoro PANER - Dublin CA, US Vinod MIRCHANDANI - San Ramon CA, US
Assignee:
APPLIED BIOSYSTEMS, LLC - Carlsbad CA
International Classification:
C12Q 1/68
US Classification:
435 611, 536 243
Abstract:
The present teachings relate to methods, compositions, and kits for detecting one or more target polynucleotide sequences in a sample, and methods compositions and kits for forming concatameric ligation products. In some embodiments of the present teachings, oligonucleotides are hybridized to complementary target polynucleotides and are ligated together to form a concatameric ligation product. In some embodiments of the present teachings, the concatameric ligation product can be amplified, and the identity and quantity of the target polynucleotides determined based on sequence introduced in the ligation reaction. Some embodiments of the present teachings provide methods for removing unligated probes from the reaction mixture. Some embodiments of the present teachings provide for highly multiplexed detection, identification, and quantification of a plurality of target polynucleotides using a variety of analytical procedures.
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