Terence M Phillips

US Patent:

7993647, Aug 9, 2011

Filed:

Jun 22, 2005

Appl. No.:

11/630880

Inventors:

Jeffrey B. Kopp - Bethesda MD, US
Terence M. Phillips - Washington DC, US
Ulrich Schubert - Jena/Thuringen, DE
John Yewdell - Silver Spring MD, US

Assignee:

The United States of America as represented by the Department of Health and Human Services - Washington DC

International Classification:

A61K 39/42
C12P 21/08
C07K 16/00
G01N 33/53

US Classification:

4241481, 4241301, 5303873, 5303888, 5303881, 53038815, 435 71

Abstract:

The present invention provides monoclonal antibodies to HIV-1 Vpr and hybridoma cell lines that produce the monoclonal antibodies to HIV-1 Vpr. Methods for use of such antibodies in the detection of HIV-1 infection are also provided.

US Patent:

44092008, Oct 11, 1983

Filed:

Apr 28, 1980

Appl. No.:

6/144326

Inventors:

William F. Feller - Bethesda MD
Judith A. Kantor - Rockville MD
Jack G. Chirikjian - Rockville MD
Terence M. Phillips - Washington DC

Assignee:

Research Corporation - New York NY

International Classification:

G01N 3356
G01N 3358

US Classification:

436516

Abstract:

A method for diagnosing mammalian breast cancer by detecting in the physiological fluid of said mammal an antigen (ACRT) having immune cross-reactivity with human reverse transcriptase, or detecting antibodies against said ACRT or detecting antibody-ACRT complexes, wherein the reverse transcriptase is substantially purified, has a molecular of about 70,000 and a sedimentation coefficient on a glycerol gradient of between 5 and 5. 5 S. A process for the purification of reverse transcriptase from human milk.