Teresa Marie Miller

US Patent:

51301059, Jul 14, 1992

Filed:

Oct 23, 1990

Appl. No.:

7/601954

Inventors:

Daniel C. Carter - Huntsville AL
Teresa Y. Miller - Falkville AL

Assignee:

The United States of America as represented by the Administrator of the
National Aeronautics and Space Administration - Washington DC

International Classification:

B01D 900
C30B 2954
C30B 3500

US Classification:

422245

Abstract:

A protein crystal growth tray assembly includes a tray that has a plurality of individual crystal growth chambers. Each chamber has a movable pedestal which carries a protein crystal growth compartment at an upper end. The several pedestals for each tray assembly are ganged together for concurrent movement so that the solutions in the various pedestal growth compartments can be separated from the solutions in the tray's growth chambers until the experiment is to be activated.

US Patent:

51048027, Apr 14, 1992

Filed:

Jul 28, 1989

Appl. No.:

7/386175

Inventors:

Percy H. Rhodes - Huntsville AL
Teresa Y. Miller - Falkville AL
Robert S. Snyder - Huntsville AL

Assignee:

The United States of America as represented by the Administrator of the
National Aeronautics and Space Administration - Washington DC

International Classification:

C12M 302
C12M 300
C12M 112
C12M 110

US Classification:

435286

Abstract:

A clinostat for simulating microgravity on cell systems carried in a fiber fixedly mounted in a rotatable culture vessel. The clinostat is rotated horizontally along its longitudinal axis to simulate microgravity or vertically as a control response. Cells are injected into the fiber and the ends of the fiber are sealed and secured to spaced end pieces of a fiber holder assembly which consists of the end pieces, a hollow fiber, a culture vessel and a tension spring with three alignment pins. The tension spring is positioned around the culture vessel with its ends abutting the end pieces and the alignment pins extend between the end pieces for alignment of the spring. After the fiber is secured, the spring is decompressed to maintain tension on the fiber while it is being rotated. This assures that the fiber remains aligned along the axis of rotation. The fiber assembly is placed in the culture vessel and culture medium is added.