Teresa S Wiley

US Patent:

7879830, Feb 1, 2011

Filed:

Aug 25, 2005

Appl. No.:

11/212001

Inventors:

Teresa S. Wiley - Santa Barbara CA, US

International Classification:

A61K 31/56
A01N 45/00

US Classification:

514170, 514169, 514178, 514182

Abstract:

Hormone compositions including bioidentical hormones dispersed in a lipid-based cream are provided in syringes for dispensation and self-administration by a user. The compositions, which are topically applied by the user, are percutaneously delivered to the vascular system of the user in accordance with a dosage protocol that causes a rhythmic and cyclic variation in the serum hormone levels that mimics the temporal variation in hormone levels present in the serum of a normal premenopausal woman.

US Patent:

20010055602, Dec 27, 2001

Filed:

Jul 20, 2001

Appl. No.:

09/910413

Inventors:

Teresa Wiley - Santa Barbara CA, US

International Classification:

A61F013/00
A61K009/70

US Classification:

424/401000, 424/443000, 424/449000

Abstract:

Compositions containing insulin formulated for topical application and a method for using the compositions for the cosmetic treatment of wrinkles. The formulation is useful for contouring the skin for the reduction of wrinkles, furrows and the like. Insulin, delivered transdermally by means of topical application to a portion of skin having wrinkles and/or furrows therein, permeates the epidermis and accumulates in the dermis and subcutaneous tissue underlying the portion of skin. The elevated insulin concentration in the dermis and subcutaneous tissue, relative to the concentration of insulin in other analogous, remotely located tissue, typically in the range of about -U/gm, stimulates the formation of a layer of adipose tissue in the insulin-rich tissue underlying the portion of skin. The fatty tissue thus formed exerts pressure on the overlying, relatively elastic portion of skin thereby stretching the skin and reducing the depth of wrinkles therein and improving the cosmetic appearance of the skin.