The present invention provides a method of treating ocular hypertension or glaucoma which comprises administering to an animal having ocular hypertension or glaucoma therapeutically effective amount of a compound represented by the general formula I; wherein X, Y, Z, D and R are as defined in the specification.
8-Azaprostaglandin Carbonate And Thiocarbonate Analogs As Therapeutic Agents
The present invention provides a compound represented by the general formula I; wherein A, Ar, X, Z, n, x, y, R and R are as defined in the specification.
8-Azaprostaglandin Carbonate And Thiocarbonate Analogs As Therapeutic Agents
The present invention provides a compound represented by the general formula I; wherein A, Ar, X, Z, n, x, y, R and Rare as defined in the specification.
Cyclohexyl Prostaglandin Analogs As Ep-Receptor Agonists
David W. Old - Irvine CA, US Robert M. Burk - Laguna Beach CA, US Thang D. Dinh - Garden Grove CA, US
Assignee:
Allergan, Inc. - Irvine CA
International Classification:
A61K 31/38 C07D 327/04
US Classification:
514443, 514529, 549 32, 560 8, 560129
Abstract:
The invention relates to the use of novel cyclohexyl analogues of E-type prostaglandins as EPagonists, in general, and, in particular as ocular hypotensives. The cyclohexyl analogues used in accordance with the invention are represented by the following formula I: wherein the wavy segments represent α or β bond, dashed line represents the presence or absence of a bond W, Y, Z, R, R, Rand Rare as defined in the specification.
Wesley K. Masenten - Irvine CA, US Keith Soo Hoo - Long Beach CA, US Peter Stubberud - Henderson NV, US Thang Victor Dinh - Westminster CA, US Elias Dagher - Aliso Viejo CA, US
Assignee:
DiTrans IP, Inc. - Menlo Park CA
International Classification:
H04L 27/06
US Classification:
375316
Abstract:
An improved complex-IF digital receiver has various improvements. The improved complex-IF digital receiver, for single or dual band applications, preferably synchronizes all of the signals to each other, which may be an integer multiple of each other. For example, the decimation filter, delta-sigma modulator, sensitivity DAC, and other circuits in the receiver can be synchronized. The delta-sigma modulator preferably includes a comparator whose input is coupled to a sensitivity DAC or synchronous dithering circuit. Ideally, the sensitivity DAC forces the comparator to trigger at every clock cycle and reduces the effect of hysteresis and offset at the input of the comparator. The receiver includes a translation circuit that translates an intermediate frequency signal to baseband, where the translation circuit preferably operates a translation ratio that is a multiple of 4.
Cyclohexyl Prostaglandin Analogs As Ep-Receptor Agonists
David W. Old - Irvine CA, US Robert M. Burk - Laguna Beach CA, US Thang D. Dinh - Garden Grove CA, US
Assignee:
Allergan, Inc. - Irvine CA
International Classification:
A61K 31/38 C07D 327/04
US Classification:
514443, 514529, 549 8, 560129
Abstract:
The invention relates to the use of novel cyclohexyl analogues of E-type prostaglandins as EPagonists, in general, and, in particular as ocular hypotensives. The cyclohexyl analogues used in accordance with the invention are represented by the following formula I:.
Cyclohexyl Prostaglandin Analogs As Ep-Receptor Agonists
David W. Old - Irvine CA, US Robert M. Burk - Laguna Beach CA, US Thang D. Dinh - Garden Grove CA, US
Assignee:
Allergan, Inc. - Irvine CA
International Classification:
A61K 31/38
US Classification:
514443, 514529
Abstract:
The invention relates to the use of novel cyclohexyl analogues of E-type prostaglandins as EPagonists, in general, and, in particular as ocular hypotensives. The cyclohexyl analogues used in accordance with the invention are represented by the following formula I:.
Gerard Medioni - Los Angeles CA, US Qian Yu - Plainsboro NJ, US Thang Ba Dinh - Los Angeles CA, US
Assignee:
University of Southern California - Los Angeles CA
International Classification:
G06K 9/00
US Classification:
382103
Abstract:
Technologies for object tracking can include accessing a video feed that captures an object in at least a portion of the video feed; operating a generative tracker to capture appearance variations of the object operating a discriminative tracker to discriminate the object from the object's background, where operating the discriminative tracker can include using a sliding window to process data from the video feed, and advancing the sliding window to focus the discriminative tracker on recent appearance variations of the object; training the generative tracker and the discriminative tracker based on the video feed, where the training can include updating the generative tracker based on an output of the discriminative tracker, and updating the discriminative tracker based on an output of the generative tracker; and tracking the object with information based on an output from the generative tracker and an output from the discriminative tracker.