Craig A. Stump - Pottstown PA Theresa M. Williams - Harleysville PA
Assignee:
Merck Co., Inc. - Rahway NJ
International Classification:
A61K 31429
US Classification:
514368, 548154, 5483027, 548218, 514393, 514375
Abstract:
The present invention is directed to peptidomimetic compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.
Christopher J Dinsmore - Schwenksville PA John H. Hutchinson - Philadelphia PA Theresa M. Williams - Harleysville PA
Assignee:
Merck Co., Inc. - Rahway NJ
International Classification:
C07D40306
US Classification:
514252, 544370
Abstract:
The present invention is directed to compounds which inhibit prenyl-protein transferases, farnesyl-protein transferase and geranylgeranyl-protein transferase type I, and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and geranylgeranyl-protein transferase type I and the prenylation of the oncogene protein RAS.
The present invention is directed to peptidomimetic macrocyclic compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.
The present invention is directed to peptidomimetic macrocyclic compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.
Christopher J. Dinsmore - Schwenksville PA Jeffrey M. Bergman - Perkasie PA Samuel L. Graham - Schwenksville PA Diem N. Nguyen - North Wales PA Gerald E. Stokker - Gwynedd Valley PA Theresa M. Williams - Harleysville PA C. Blair Zartman - Hatfield PA
Assignee:
Merck Co., Inc. - Rahway NJ
International Classification:
C07D26700
US Classification:
514250, 540469
Abstract:
The present invention is directed to peptidomimetic piperazine-containing macrocyclic compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.
Craig A. Stump - Pottstown PA Theresa M. Williams - Harleysville PA
Assignee:
Merck Co., Inc. - Rahway NJ
International Classification:
C07D49808
US Classification:
514397, 540456, 540457
Abstract:
The present invention is directed to peptidomimetic macrocyclic compounds that inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.
Christopher S. Burgey - Philadelphia PA, US Zhengwu J. Deng - Eagleville PA, US Diem N. Nguyen - Harleysville PA, US Daniel V. Paone - Blue Bell PA, US Anthony W. Shaw - Harleysville PA, US Theresa M. Williams - Harleysville PA, US
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C07D401/14 A61K031/55
US Classification:
51421208, 540524
Abstract:
The present invention is directed to compounds of Formula I: and Formula II: (where variables R, R, R, R, A, B, G, J, Q, T, U, V, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Ian M. Bell - Harleysville PA, US Cory R. Theberge - King of Prussia PA, US Theresa M. Williams - Harleysville PA, US C. Blair Zartman - Hartfield PA, US Steven N. Gallicchio - Wyndmoor PA, US
The present invention is directed to compounds that are antagonists of CGRP receptors and that are useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Oct 2013 to 2000 Cashier/ Customer ServiceAC Moore
May 2014 to Dec 2014 Produce ClerkPrice Chopper, Wilkes Barre, PA
Nov 2008 to Aug 2013 Cashier/Supervisor/Pharmacy TechWalmart
Jun 2007 to Feb 2008 Cashier/Customer serviceTarget Columbia, SC Oct 2002 to Jul 2003 Cashier/Customer ServiceWalmart Winnsboro, SC May 1999 to May 2001 Cashier/Customer ServiceSkyline Motor Inn New York, NY May 1995 to May 1998 HousekeeperNew York City Department Of Perssonnel New York, NY Sep 1993 to Feb 1994 File Clerk/Office Assistant
Procura Management Inc Norristown, PA Jul 2011 to Mar 2013 Case Manager AssistantER Registration Coatesville, PA Dec 2009 to Apr 2011 Registration ClerkER Registration Pottstown, PA Jun 2005 to Dec 2009 Registration ClerkDowntown Emergency Service Center Seattle, WA Aug 2001 to Jun 2005 Administrative Support Staff
Education:
Montgomery County Community College Blue Bell, PA Dec 2012 Liberal ArtsWhittier High School Whittier, CA Jun 1991 Diploma
Jun 2005 to 2000 File ClerkBargain News, LLC Trumbull, CT Sep 2007 to Jun 2013 Graphic ArtistEqual Opportunity Publications, Inc Melville, NY Oct 2004 to Dec 2004 InternWilliams & Bellenot Monroe, CT 2001 to 2004 File Clerk
Education:
Long Island University/C.W. Post Campus Brookville, NY 2001 to 2005 Bachelor of Fine Arts in Digital Arts and Design
Skills:
Proficient in the use and application of the following programs: Adobe InDesign, Adobe Photoshop, Adobe Illustrator, QuarkXPress, Flash, Dreamweaver, Director, Strata 3D Pro, Adobe Premiere, Adobe After Effects
Gateway STEM High School St. Louis, MO Jan 1999 to Jun 2014 Computer Teacher and Math TeacherISS Monitor St. Louis, MO Sep 1995 to Jun 1998 Part-time Math Teacher
Education:
Missouri Baptist University St. Louis, MO 2007 M.S. in EducationMissouri Baptist University St. Louis, MO 1995 Bachelor of Science in Mathematics
Feb 2011 to Apr 2013 Home Health AideEnglewood Hospital Medical Center Englewood, NJ Jul 2010 to Jan 2011 Linen DepartmentSultan Chemist Inc. Englewood, CO Apr 1992 to Nov 2008 Assistant Supervisor
Education:
Vance Granvillie Community College Henderson, NC 1978 to 1979 certicates in Human Development Research
Marken's Jewelers ft Pandora Valley Stream, NY Nov 2013 to Jan 2014 Sales Associatecolumbia presbyterian New York, NY Jan 2013 to Aug 2013 ReceptionistChick's Nursery Brooklyn, NY May 2011 to Sep 2011 Sales associate/cashier
Education:
High School for Medical Professions Brooklyn, NY 2009 to 2013 High school diploma in medical
Googleplus
Theresa Williams
Lived:
Williamstown, nj Middlesex, nj
Work:
ShopRite - Cashier (9)
Education:
Ashworth University - Small business management
Relationship:
In_a_relationship
About:
21 years old. addicted to coffee and mountain dew. 2 cats (Angel Molly and Wawa). Unofficial makeup artist. cashier. i work too much to enjoy life. ive been with my amazing boyfriend for THREE AND A H...
Bragging Rights:
I make a mean steak
Theresa Williams
Work:
HammerFit Athletic - Manager
Education:
Essex junction high school
Theresa Williams
Work:
Ross H Williams OD - Insurance biller
Education:
Anaheim High, Biola University - El ed
Theresa Williams
Education:
University of Phoenix - Social Work, Mercy College - Organizational Management, Coastline Community College - Human Resource Management
Theresa Williams
Work:
Self Employed - Biblical Author
Education:
Dekalb Tech - Business
About:
I AM 33 WITH 2 BEAUTIFULL LITTLE GIRLS. I HAVE JUST WRITTEN A BOOK CALLED: (WHISPERED WORDS OF LOVE FROM GOD)  PLEASE VISIT ME @ AMAZON FOR THE READ WITHIN THE BOOK FEATURE!  ALSO AVAILABLE ON KOBO !...
Tagline:
33 Yr. Old Mommy of 2 Girls!
Theresa Williams
Work:
Theresa Williams
Education:
Janay Williams, Ashley Williams
Theresa Williams
Work:
My brain
About:
Those three words are said too much, but not enough... We all carry these things, that no one else can see. They hold us down like anchors, they drown us out at sea...
Lincoln Elementary School Ottawa IL 1970-1975, Shepherd Middle School Ottawa IL 1976-1978
Community:
Theresa Hicks, Diana Walker, Geneva Chesnut, Patrick Pillman, Harvey Havens, Kim Forsythe, Carla Cook, Sheila Matthews, Frederick Perkins, Dale White, Pamela Wengler, Michael Jones
Biography:
LifeHello everyone interested in reading this. I live in Seguin, Tx, am now divorc...
Walter S. Miller Elementary School Levittown PA 1965-1968, Delaplaine McDaniel Elementary School Philadelphia PA 1968-1972, Edwin H. Vare Junior High School Philadelphia PA 1973-1976
Community:
Richard Crockett, Kevin Myers, Martin Menaldi, Rosalind Smith
Biography:
Life
Hi everyone! It's been a long time! I left good old Philly in 82 and moved to ...
frantically threw herself in front of her children as the boys tried to run to safety. The mother was shot in the right calf while shielding her 15-year-old son on the ground. The other three boys scattered in opposite directions, Taylors sister, Theresa Williams, told ABC Dallas affiliate WFAA.
Date: Jul 08, 2016
Category: World
Source: Google
Latest in Dallas: Transit agency IDs officer killed in Dallas
A sister of 37-year-old Shetamia Taylor says Taylor was at the protests Thursday night with her four sons, ages 12 to 17. Theresa Williams says that when the shooting began, Taylor threw herself over her sons. She was undergoing surgery early Friday after being shot in the right calf.
Date: Jul 08, 2016
Source: Google
Hero mom shot while shielding son from bullets in Dallas attack
"She jumped on top to cover him on the ground as she pushed him in between two cars in the curb," Taylor's sister, Theresa Williams, told local station WFAA. "All she could think about was her other three boys where are they at."
Date: Jul 08, 2016
Category: U.S.
Source: Google
Among Dallas sniper victims: A newlywed, a veteran, parents
Taylor was fed up so she decided to march with her sons ages 12, 13, 15 and 17 her sister, Theresa Williams, said. Shes got four boys who she just wants to be able to be peacefully out here in the world, Williams said.
Date: Jul 08, 2016
Category: U.S.
Source: Google
Dead gunman in Dallas shootings ID'd; police say he wanted 'to kill white people'
Theresa Williams told the Associated Press that the injured civilian was her sister, 37-year-old Shetamia Taylor.Williams said her sister was at the protests Thursday night with her four sons, ages 12 to 17.
Date: Jul 08, 2016
Category: U.S.
Source: Google
Fire forces evacuation of campus, homes in Calif. - KSAZ 10
About 100 miles to the east, two homes, a number of outbuildings and several vehicles were destroyed, and two other homes were damaged in a 5-acre grass fire that prompted the evacuation of an elementary school in Jurupa Valley, said Theresa Williams, a spokeswoman for CalFire.
Date: May 02, 2013
Category: U.S.
Source: Google
Gun control debate: Standing by families of the slain shows Obama's humanity
Honored not exploited, was Theresa Williams self-description. Her son, Aaron Kidd, a Suitland High school student was shot and killed near his home in February. He was one of six high school students in Prince Georges County murdered since August. I dont want the president to back away beca
ith stores opening earlier, bargain-obsessed shoppers often are sleep-deprived and short-tempered. Add in the online-coupon phenomenon, which feeds the psychological hunger for impossible bargains, and you've got a recipe for trouble, said Theresa Williams, a marketing professor at Indiana University.