Thomas R Arnold

US Patent:

52234967, Jun 29, 1993

Filed:

Apr 23, 1992

Appl. No.:

7/872866

Inventors:

Alexander R. Cazers - Richland MI
K. Thomas Koshy - Kalamazoo MI
Prem S. Jaglan - Kalamazoo MI
Robert J. Yancey - Richland MI
Terry J. Gilbertson - Kalamazoo MI
Thomas S. Arnold - Kalamazoo MI
David B. Johnson - Portage MI
Catherine L. Gatchell - Portage MI

Assignee:

The Upjohn Company - Kalamazoo MI

International Classification:

C07D50136
A61F 31545

US Classification:

514206

Abstract:

Cephalosporin compounds of Formulas II ##STR1## where R is hydrogen or a pharmaceutical cation, in which case R. sub. 1 is not present, or R is hydrogen or a chemical bond when R. sub. 1 is an acid addition salt anion, and R. sub. 2 is (a) hydrogen, (b) a duplicate of the formula I compound to form a dimer, (c) an aminocarbonylmethyl, or (d) an --SR. sub. 3 group where R. sub. 3 is alkyl, cyclohexyl, phenyl, chloro-substituted phenyl, nitro-substituted phenyl, benzyl or furfuryl, have been found to be valuable as antibiotics for treating warm-blooded animals to combat pathogenic bacterial infections which cause diseases such as the commonly known "shipping fever".

US Patent:

51341379, Jul 28, 1992

Filed:

May 9, 1990

Appl. No.:

7/460346

Inventors:

Alexander R. Cazers - Richland MI
K. Thomas Koshy - Kalamazoo MI
Prem S. Jaglan - Kalamazoo MI
Robert J. Yancey - Richland MI
Terry J. Gilbertson - Kalamazoo MI
Thomas S. Arnold - Kalamazoo MI
David B. Johnson - Portage MI
Catherine L. Gatchell - Portage MI

Assignee:

The Upjohn Company - Kalamazoo MI

International Classification:

C07D50136
A61K 31545

US Classification:

514206

Abstract:

Cephalosporin compounds of Formulas II ##STR1## where R is hydrogen or a pharmaceutical cation, in which case R. sub. 1 is not present, or R is hydrogen or a chemical bond when R. sub. 1 is an acid addition salt anion, and R. sub. 2 is (a) hydrogen, (b) a duplicate of the formula I compound to form a dimer, (c) an aminocarbonylmethyl, or (d) an --SR. sub. 3 group where R. sub. 3 is alkyl, cyclohexyl, phenyl, chloro-substituted phenyl, nitro-substituted phenyl, benzyl or furfuryl, have been found to be valuable as antibiotics for treating warm-blooded animals to combat pathogenic bacterial infections which cause diseases such as the commonly known "shipping fever".

Address:

609 Missouri Riv Dr, Adrian, MI 49221

VIN:

1G2ZH361674102573

Make:

PONTIAC

Model:

G6

Year:

2007