Thomas J Carroll

US Patent:

47897937, Dec 6, 1988

Filed:

Feb 24, 1987

Appl. No.:

7/018871

Inventors:

George J. Ehni - Dallas TX
Jy-Der Tai - Plano TX
Edison H. Chiu - Richardson TX
Thomas A. Carroll - Boulder CO

Assignee:

Texas Instruments Incorporated - Dallas TX

International Classification:

H03K 17687
H01L 513

US Classification:

307303

Abstract:

A CMOS output pair provides rapid switching speed while avoiding excessive noise levels developed across the power supply parasitic inductance. Both the P-channel and N-channel transistors of the output pair actually comprise a plurality of sub-transistors with their source to drain current paths connected in parallel. As a result of novel RC coupling of a switching signal from gate to gate of either of the plurality of sub-transistors, the sub-transistors are caused to turn on sequentially. Since none of the sub-transistors is capable of supporting the current that must be carried by the totality of sub-transistors making up either the P-channel or N-channel transistor, the increments of current as each sub-transistor turns on are small relative to the total.

US Patent:

20190254266, Aug 22, 2019

Filed:

Oct 27, 2016

Appl. No.:

15/771243

Inventors:

- Minneapolis MN, US
- St. Paul MN, US
- Austin TX, US
Thomas Carroll - Dallas TX, US

Assignee:

Regents of the University of Minnesota - Minneapolis MN
Recombinetics, Inc. - St. Paul MN
Board of Regents of the University of Texas System - Austin TX

International Classification:

A01K 67/027

Abstract:

Human or humanized tissues and organs suitable for transplant are disclosed herein. Gene editing of a host animal provides a niche for complementation of the missing genetic information by donor stem cells. Editing of a host genome to knock out or debilitate genes responsible for the growth and/or differentiation of a target organ and injecting that animal at an embryo stage with donor stem cells to complement the missing genetic information for the growth and development of the organ. The result is a chimeric animal in which the complemented tissue (human/humanized organ) matches the genotype and phenotype of the donor. Such organs may be made in a single generation and the stem cell may be taken or generated from the patient's own body. As disclosed herein, it is possible to do so by simultaneously editing multiple genes in a cell or embryo creating a “niche” for the complemented tissue. Multiple genes can be targeted for editing using targeted nucleases and homology directed repair (HDR) templates in vertebrate cells or embryos.

Address:

4836 Rdg Cir, Benbrook, TX 76126

VIN:

3GYEK62847G103167

Make:

CADILLAC

Model:

ESCALADE EXT

Year:

2007