Thomas F Chen

US Patent:

D559232, Jan 8, 2008

Filed:

Dec 15, 2006

Appl. No.:

29/275152

Inventors:

Wen Ku - Cupertino CA, US
Sally Li - Los Altos CA, US
Thomas Chen - Foster City CA, US
Yi-Wen Chen - Taipei, TW

Assignee:

Fortemedia, Inc. - Cupertino CA
MVOX Technologies, Inc. - Cupertino CA

International Classification:

1401

US Classification:

D14223

US Patent:

7770140, Aug 3, 2010

Filed:

Feb 5, 2008

Appl. No.:

12/026141

Inventors:

Robert H. Bell - Austin TX, US
Thomas W. Chen - Austin TX, US
Venkat R. Indukuru - Austin TX, US
Pattabi M. Seshadri - Austin TX, US
Madhavi G. Valluri - Leander TX, US

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G06F 17/50

US Classification:

716 4, 716 1

Abstract:

A test system or simulator includes an IC test application sampling software program that executes test application software on a semiconductor die IC design model. The test application sampling software includes trace, simulation point, CPI error, clustering and other programs. IC designers utilize the test application sampling software to evaluate the performance characteristics of IC designs with test software applications. The test application sampling software generates basic block vectors (BBVs) and fly-by vectors (FBVs) from instruction trace analysis of test application software. The test application sampling software analyzes microarchitecture dependent information that it uses to generate the FBVs. Test application sampling software generates a reduced representative test application software program from the BBV and FBV data utilizing an instruction budgeting method. Designers use the test system with test application sampling software to evaluate IC design models by using the representative test application software program.

US Patent:

7844928, Nov 30, 2010

Filed:

Jan 11, 2008

Appl. No.:

11/972747

Inventors:

Robert H. Bell - Austin TX, US
Thomas W. Chen - Austin TX, US
Richard J. Eickemeyer - Rochester MI, US
Venkat R. Indukuru - Austin TX, US
Pattabi M. Seshadri - Austin TX, US
Madhavi G. Valluri - Leander TX, US

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G06F 17/50

US Classification:

716 4, 716 1

Abstract:

A test system or simulator includes an IC benchmark software program that executes application software on a semiconductor die IC design model. The benchmark software includes trace, simulation point, clustering and other programs. IC designers utilize the benchmark software to evaluate the performance characteristics of IC designs with customer user software applications. The benchmark software generates basic block vectors BBVs from instruction traces of application software. The benchmark software analyzes data dependent information that it appends to BBVs to create enhanced BBVs or EBBVs. The benchmark software may graph the EBBV information in a cluster diagram and selects a subset of EBBVs as a representative sample for each program phase. Benchmarking software generates a reduced application software program from the representative EBBV samples. Designers use the test system with benchmarking software to evaluate IC design model modifications by using the representative reduced application software program.

US Patent:

7981917, Jul 19, 2011

Filed:

Mar 26, 2008

Appl. No.:

12/056192

Inventors:

Axel H. Schönthal - Los Angeles CA, US
Nicos A. Petasis - Hacienda Heights CA, US
Florence M. Hofman - Venice CA, US
Stan G. Louie - Fullerton CA, US
Thomas C. Chen - La Canada CA, US

Assignee:

University of Southern California - Los Angeles CA

International Classification:

A61K 31/415

US Classification:

514406, 514256

Abstract:

The present invention provides a method for inducing apoptosis in selected cells by aggravating ER-stress. The aggravation of ER-stress is achieved in a specific manner by inhibiting SERCA (sarcoplasmic/endoplasmic reticulum calcium ATPase), leading to elevated level of cytoplasmic calcium concentration, yet without inhibiting the activity of COX-2 (cyclooxygenase-2) or triggering the release of histamine. Induction of apoptosis may be enhanced by first inducing or further aggravating ER-stress through inhibition of proteasome or proteases. Also provided are compounds and compositions useful as ER-stress aggravating agents, methods for screening, selecting, identifying and designing the same and methods for treating diseased conditions by inducing apoptosis through specific and selective aggravation of ER-stress.

US Patent:

8236862, Aug 7, 2012

Filed:

Feb 4, 2010

Appl. No.:

12/700614

Inventors:

Thomas C. Chen - Los Angeles CA, US
Clovis O. da Fonseca - Rio de Janeiro, BR
Thereza Quirico dos Santos - Niterói, BR
Gilberto Schwartsmann - Porto Alegre, BR

Assignee:

University of Southern California - Los Angeles CA

International Classification:

A61K 31/045

US Classification:

514729, 514724, 554229

Abstract:

This invention provides a compositions for transport of a therapeutic agent. The compositions contain a therapeutic agent and a monoterpene or an analog thereof. In one aspect, the monoterpene is perillyl alcohol (POH) or an analog thereof. In one aspect, the therapeutic agent is provided in an amount effective to treat the disease or subject of choice.

US Patent:

20070183155, Aug 9, 2007

Filed:

Feb 8, 2007

Appl. No.:

11/704737

Inventors:

Thomas Chen - Chino CA, US

International Classification:

F21V 23/04

US Classification:

362276

Abstract:

A decorative entertaining unit includes a decorative ornament body and an entertaining unit. The decorative ornament body has a base portion attached on a user's body, and a decorative portion extended from the base portion, wherein the decorative portion has a predetermined aesthetic appearance for serving general decorative function. The entertaining unit is embedded into the decorative ornament body, and comprises an illuminating unit adapted to operate between a normal mode and an enhanced decoration mode, wherein in the normal mode, the illuminating unit is deactivated to allow plain decoration from the decorative ornament body, wherein in the enhanced decoration mode, the illuminating unit is activated to generate a predetermined pattern of illumination so as to provide an illuminating decorative effect of the decorative ornament body.

US Patent:

20090276190, Nov 5, 2009

Filed:

Apr 30, 2008

Appl. No.:

12/112034

Inventors:

Thomas W. Chen - Austin TX, US
Venkat R. Indukuru - Austin TX, US
Alexander E. Mericas - Austin TX, US
Pattabi M. Seshadri - Austin TX, US
Madhavi G. Valluri - Leander TX, US

Assignee:

INTERNATIONAL BUSINESS MACHINES CORPORATION - Armonk NY

International Classification:

G06F 17/50

US Classification:

703 1

Abstract:

A test system or simulator includes an integrated circuit (IC) benchmark software program that executes workload program software on a semiconductor die IC design model. The benchmark software program includes trace, simulation point, basic block vector (BBV) generation, cycles per instruction (CPI) error, clustering and other programs. The test system also includes CPI stack program software that generates CPI stack data that includes microarchitecture dependent information for each instruction interval of workload program software. The CPI stack data may also include an overall analysis of CPI data for the entire workload program. IC designers may utilize the benchmark software and CPI stack program to develop a reduced representative workload program that includes CPI data as well as microarchitecture dependent information.

US Patent:

20100234669, Sep 16, 2010

Filed:

Mar 11, 2009

Appl. No.:

12/402437

Inventors:

Kevin Armstrong - Irvine CA, US
Thomas Chen - La Canada CA, US

International Classification:

A61M 36/12

US Classification:

600 7

Abstract:

There is provided herein a brachytherapy delivery system for the internal delivery and positioning of therapeutic agent, most particularly, a discrete radiation emitting particulate, within or in proximity to a vertebral or other bony tumor. The system comprises an elongated bone cannula having a proximal and a distal end, the distal end being suitable for disposition within bone. The bone cannula further comprises a bore disposed longitudinally therethrough suitable to axially and slidably receive an elongated and cannulated therapy delivery apparatus through which the therapeutic agent is delivered.