Oxford Global Resources Jun 2013 - Jul 2016
Consultant
Newco Jun 2013 - Jul 2016
Entrepreneur and Innovator
Endo Pharmaceuticals Jun 2011 - Mar 2012
Senior Principal Scientist
American Medical Systems Apr 2006 - May 2011
Senior Principal Scientist
Medtronic Mar 1993 - Apr 2006
R and D Project Manager and Principal Scientist
Education:
Iowa State University 2006 - 2010
Master of Science, Doctorates, Masters, Doctor of Philosophy
University of St. Thomas 1994 - 1998
Master of Business Administration, Masters, Marketing, Management
Iowa State University 1988 - 1991
Master of Science, Doctorates, Masters, Doctor of Philosophy, Biomedical Engineering
University of Minnesota
Bachelors, Bachelor of Science, Chemical Engineering, Chemistry
Skills:
Drug Delivery Biomaterials Medical Devices R&D Biomedical Engineering Nanotechnology Pharmaceutical Industry Biotechnology Tissue Engineering Project Management Polymer Science Cell Therapy Analytical Chemistry Targeted Drug Delivery In Vitro Cross Functional Team Leadership Wound Care Molecular Biology Polymers Pharmaceutical Sciences Preclinical Animal Models Protein Delivery Business Strategy New Venture Development Cancer Research Anti Restenosis Research Polymer Coating Technology Regulatory Requirements Fda Gmp Glp Biostatistics Nda Quality System Compliance 21 Cfr Life Sciences
Interests:
New Job Opportunity Start Up Medical Device Consulting In Drug/Device Combination Venture
Thomas Q. Dinh - Minnetonka MN Rodney G. Wolff - Minnetonka Beach MN Eric P. Berg - Plymouth MN
Assignee:
Medtronic Inc. - Minneapolis MN
International Classification:
A61L 1554
US Classification:
427 224, 427 228, 427 231
Abstract:
A device useful for localized delivery of a therapeutic material is provided. The device includes a structure including a porous material; and a water-insoluble salt of a therapeutic material dispersed in the porous material. The water-insoluble salt is formed by contacting an aqueous solution of a therapeutic salt with a heavy metal water-soluble salt dispersed throughout a substantial portion of the porous material. The porous material can be made of a polymer other than fibrin with fibrin incorporated into the pores, which can be the only layer of polymeric material on the medical device (e. g. , stent). A new method for preparing a porous polymer material on a medical device.
Medical Device For Delivering A Therapeutic Substance And Method Therefor
Eric P. Berg - Plymouth MN Thomas Q. Dinh - Minnetonka MN
Assignee:
Medtronic, Inc. - Minneapolis MN
International Classification:
A61F 206
US Classification:
623 142, 604266, 604269, 6048911, 604265, 623 143
Abstract:
A device useful for localized delivery of a therapeutic material is provided. The device includes a structure including a porous material; and a water-insoluble salt of a therapeutic material dispersed in the porous material. The water-insoluble salt is formed by contacting an aqueous solution of a therapeutic salt with a heavy metal water-soluble salt dispersed throughout a substantial portion of the porous material. The heavy metal water-soluble salt can be dispersed in the porous material so that the device can be sterilized and the therapeutic material can be loaded in the device in situ, for example, just prior to use. The therapeutic material is preferably a heparin or heparin derivative or analog which renders the material antithrombotic as an implantable or invasive device.
The present invention provides a stent for delivering drugs to a vessel in a body, including a stent framework with a plurality of reservoirs formed therein, a drug polymer positioned in the reservoirs, and a polymer layer positioned on the drug polymer. The present invention also provides a method of manufacturing a drug-polymer stent and a method of treating a vascular condition using the drug-polymer stent.
Medical Device Having A Surface Including A Biologically Active Agent Therein, And Methods
Thomas Q Dinh - Minnetonka MN, US Rodolfo Padua - Richfield MN, US
Assignee:
Medtronic, Inc. - Minneapolis MN
International Classification:
A61K 9/22 A61F 2/00
US Classification:
6048901, 424426
Abstract:
The present invention provides a medical device, and methods of preparing and using a medical device. The medical device has a surface including a biologically active agent therein. The methods are particularly useful for preparing, for example, coated stents having a biologically active agent within the coating.
Apparatus And Methods Of Treatment Of Pathologic Proliferative Conditions Uterine Tissue
Rosa K. Canifax - Minnetonka MN, US Thomas Q. Dinh - Minnetonka MN, US Edouard A. Koullick - Minnetonka MN, US Mark S. Bouchier - Minnetonka MN, US
Assignee:
AMS Research Corporation - Minnetonka MN
International Classification:
A61M 31/00
US Classification:
604285
Abstract:
A uterine fibroid treatment device providing for localized delivery of one or more treatment drugs for treating various uterine conditions including, for example, uterine fibroids, abnormal uterine bleeding, pelvic adhesions and endometriosis. Generally, the uterine treatment device comprises a physical positioning element that can be inserted, positioned and maintained in close proximity to the uterine tissue to be treated. The treatment drugs delivered to the treatment location can include various combinations of anti-proliferative agents and angiogenesis inhibitors to provide different treatments concurrently. In some embodiments, the physical element can also serve the dual purpose of delivering the treatment drugs while simultaneously cutting off blood flow to a mature fibroid to initiate hypoxic/ischemic conditions within the mature fibroid.
Medical Device For Delivering A Therapeutic Substance And Method Therefor
Eric Berg - Plymouth MN, US Thomas Dinh - Minnetonka MN, US
Assignee:
Medtronic Vascular, Inc.
International Classification:
A61F002/06
US Classification:
623/001420
Abstract:
A device useful for localized delivery of a therapeutic material is provided. The device includes a structure including a porous material; and a water-insoluble salt of a therapeutic material dispersed in the porous material. The water-insoluble salt is formed by contacting an aqueous solution of a therapeutic salt with a heavy metal water-soluble salt dispersed throughout a substantial portion of the porous material. The heavy metal water-soluble salt can be dispersed in the porous material so that the device can be sterilized and the therapeutic material can be loaded in the device in situ, for example, just prior to use. The therapeutic material is preferably a heparin or heparin derivative or analog which renders the material antithrombotic as an implantable or invasive device.
Methods And Apparatus For Treatment Of Aneurysmal Tissue
Brian Fernandes - Roseville MN, US Thomas Dinh - Minnetonka MN, US Laura Christoferson - Ramsey MN, US David Brin - Topsfield MA, US David Tseng - Miramar FL, US
International Classification:
A61F002/06
US Classification:
623/001130
Abstract:
The present invention encompasses methods and apparatus for aiding aneurysm repair using local delivery of therapeutic agents. In one embodiment according to the present invention, there is provided an intravascular treatment device comprising a stent graft including one or more therapeutic agents in a time-release coating.
Active Agent Delivery Systems Including A Miscible Polymer Blend, Medical Devices, And Methods
Thomas Dinh - Minnetonka MN, US Randall Sparer - Andover MN, US SuPing Lyu - Maple Grove MN, US Kiem Dang - Blaine MN, US Christopher Hobot - Tonka Bay MN, US
International Classification:
A61K009/14
US Classification:
424422000, 424486000
Abstract:
An active agent delivery system that includes two or more active agents and two or more layers of polymers; wherein at least one layer includes miscible polymer blend comprising two or more miscible polymers; and further wherein delivery of at least one active agent occurs predominantly under permeation control.