Thomas J Gates

US Patent:

54179807, May 23, 1995

Filed:

Jun 29, 1994

Appl. No.:

8/268865

Inventors:

William J. Goldman - Ambler PA
Thomas N. Gates - Doylestown PA

Assignee:

McNeil-PPC, Inc. - Milltown NJ

International Classification:

A61K 920

US Classification:

424464

Abstract:

This invention relates to a pharmaceutical composition for treating the symptoms of overindulgence comprising an analgesic effective amount of acetaminophen or a non-steroidal anti-inflammatory drug and a gastric acid inhibiting effective amount of an H. sub. 1 or H. sub. 2 blocker, proton pump inhibitor or a combination thereof and methods of treating the symptoms of overindulgence comprising administering such pharmaceutical compositions.

US Patent:

58542671, Dec 29, 1998

Filed:

Jun 2, 1995

Appl. No.:

8/459182

Inventors:

Roger Berlin - Haverford PA
Thomas N. Gates - Bonita Springs FL
Thomas Simon - Berwyn PA

Assignee:

Merck & Co., Inc. - Rahway NJ
Mc Neil-PPC, Inc. - Skillman NJ

International Classification:

A61K 31425

US Classification:

514370

Abstract:

A method for preventing heartburn episodes in a patient susceptible to suffering heartburn episodes following ingestion of heartburn-inducing food or beverage, comprising administering to the patient, 30 minutes prior to consumption by the patient of the food or beverage, a composition comprising an amount of famotidine of 10 mg.

US Patent:

52041182, Apr 20, 1993

Filed:

Apr 29, 1992

Appl. No.:

7/876824

Inventors:

William J. Goldman - Ambler PA
Thomas N. Gates - Doylestown PA

Assignee:

McNeil-PPC, Inc. - Milltown NJ

International Classification:

A61K 908
A61K 910
A61K 914

US Classification:

424489

Abstract:

This invention relates to a pharmaceutical composition for treating the symptoms of overidulgence comprising an analgesic effective amount of acetaminophen or a non-steroidal anti-inflammatory drug and a gastric acid inhibiting effective amount of an H. sub. 1 or H. sub. 2 blocker, proton pump inhibitor or a combination thereof and methods of treating the symptoms of overindulgence comprising administering such pharmaceutical compositions.

US Patent:

52885070, Feb 22, 1994

Filed:

Jul 29, 1992

Appl. No.:

7/921879

Inventors:

Robert T. Sims - Holicong PA
Thomas N. Gates - Doylestown PA
William Slivka - Philadelphia PA

Assignee:

Merck & Co., Inc. - Rahway NJ
McNeill-PPC, Inc. - Fort Washington PA

International Classification:

A61K 3306
A61K 3308
A61K 3310

US Classification:

424682

Abstract:

This invention relates to a pharmaceutical composition for use in the treatment of pain and inflammation and the treatment of acid indigestion, sour stomach, heartburn and symptoms of upset stomach associated with these conditions in a mammalian organism, said composition comprising: (i) an analgesically and anti-inflammatory effective amount of (S)-ibuprofen, or a salt thereof, substantially free of (R)-ibuprofen; (ii) an amount effective in the treatment of acid indigestion, sour stomach and/or heartburn of at least one of the antacids; and (iii) optionally, an amount effective in treating excess gas and flatulence of an anti-gas agent.

US Patent:

52603377, Nov 9, 1993

Filed:

Jul 29, 1992

Appl. No.:

7/921882

Inventors:

Robert T. Sims - Holicong PA
Thomas N. Gates - Doylestown PA
William Slivka - Philadelphia PA

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

A61K 3119
A61K 31135

US Classification:

514570

Abstract:

This invention relates to pharmaceutical compositions for use in the treatment of pain and inflammation and the treatment of muscle spasms and associated pain, soreness and tightness of muscles in mammalian organism, said composition comprising: (i) an analgesically and anti-inflammatory effective amount of (S)-ibuprofen, or a salt thereof, substantially free of (R)-ibuprofen; and (ii) an amount effective in the treatment of muscle spasms of at least one of the muscle relaxants, or a therapeutically active stereoisomer thereof, substantially free of its other stereoisomers.