Thomas G Hendrickson

US Patent:

8217035, Jul 10, 2012

Filed:

Jan 22, 2007

Appl. No.:

12/161537

Inventors:

Matthew Burger - Emeryville CA, US
Zhi-Jie Ni - Emeryville CA, US
Sabina Pecchi - Emeryville CA, US
Gordana Atallah - Emeryville CA, US
Sarah Bartulis - Emeryville CA, US
Kelly Frazier - Emeryville CA, US
Aaron Smith - Emeryville CA, US
Joelle Verhagen - Emeryville CA, US
Yanchen Zhang - Emeryville CA, US
Allan Wagman - Emeryville CA, US
Simon Ng - Emeryville CA, US
Keith Pfister - Emeryville CA, US
Daniel Poon - Emeryville CA, US
Alicia Louie - Emeryville CA, US
Teresa Pick - Emeryville CA, US
Paul Barsanti - Emeryville CA, US
Edwin Iwanowicz - Emeryville CA, US
Wendy Fantl - Emeryville CA, US
Thomas Hendrickson - Emeryville CA, US
Mark Knapp - Emeryville CA, US
Hanne Merritt - Emeryville CA, US
Charles Voliva - Emeryville CA, US
Marion Wiesmann - Emeryville CA, US
Xiaohua Xin - Emeryville CA, US

Assignee:

Novartis AG - Basel

International Classification:

A61K 31/535
C07D 413/14

US Classification:

5142322, 544122

Abstract:

Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases.

US Patent:

8563549, Oct 22, 2013

Filed:

May 14, 2012

Appl. No.:

13/471111

Inventors:

Matthew Burger - Emeryville CA, US
Zhi-Jie Ni - Freemont CA, US
Sabina Pecchi - Oakland CA, US
Sarah Bartulis - Emeryville CA, US
Kelly Frazier - Emeryville CA, US
Aaron Smith - Freemont CA, US
Joelle Verhagen - Emeryville CA, US
Yanchen Zhang - Emeryville CA, US
Allan Wagman - Belmont CA, US
Simon Ng - Walnut Creek CA, US
Keith Pfister - San Ramon CA, US
Daniel J. Poon - Piedmont CA, US
Alicia Louie - Emeryville CA, US
Teresa Pick - Danville CA, US
Paul Barsanti - Pleasant Hill CA, US
Edwin Iwanowicz - Emeryville CA, US
Wendy Fantl - Emeryville CA, US
Thomas Hendrickson - Emeryville CA, US
Mark Knapp - Oakland CA, US
Hanne Meritt - Emeryville CA, US
Charles Voliva - Emeryville CA, US
Marion Wiesmann - Bottmingen, CH
Xiahua Xin - Emeryville CA, US

Assignee:

Novartis AG - Basel

International Classification:

A61K 31/535
C07D 413/14

US Classification:

5142322, 544122

Abstract:

Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases.

US Patent:

20070027150, Feb 1, 2007

Filed:

Apr 14, 2006

Appl. No.:

11/404372

Inventors:

Cornelia Bellamacina - Castro Valley CA, US
Abran Costales - El Cerrito CA, US
Brandon Doughan - Eugene OR, US
Susan Fong - Richmond CA, US
Zhenhai Gao - Hercules CA, US
Thomas Hendrickson - Encinitas CA, US
Barry Levine - Lafayette CA, US
Xiaodong Lin - Walnut Creek CA, US
Timothy Machajewski - Martinez CA, US
Christopher McBride - Oakland CA, US
Maureen McKenna - Pinole CA, US
Kris Mendenhall - Concord CA, US
Alice Rico - Castro Valley CA, US
Cynthia Shafer - Moraga CA, US
Yi Xia - Foster City CA, US
Yasheen Zhou - Moraga CA, US

International Classification:

A61K 31/5377
A61K 31/517
C07D 413/02
C07D 403/02

US Classification:

514234200, 544123000, 544284000, 514252170, 514255050, 514266200, 514266220

Abstract:

2-Amino-quinazolin-5-one compounds, stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-quinazolin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the 2-amino-quinazolin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cell proliferative diseases.

US Patent:

40891038, May 16, 1978

Filed:

Jun 4, 1976

Appl. No.:

5/693049

Inventors:

Thomas E. Hendrickson - Minneapolis MN
Jack S. T. Huang - New Hope MN
Wolfgang Tetzlaff - Hopkins MN

Assignee:

Honeywell Inc. - Minneapolis MN

International Classification:

B01J 1700

US Classification:

29577C

Abstract:

Methods for monolithic integrated circuit construction are presented wherein component device-isolating region self-alignment is provided and also, where an element of the device is provided through independent dopant provision steps to allow design flexibility in providing that device element and associated integrated circuit devices. The method is especially applicable to bipolar device construction.

US Patent:

47977248, Jan 10, 1989

Filed:

Jun 30, 1982

Appl. No.:

6/393891

Inventors:

Clifford H. Boler - New Hope MN
Marc D. Hartranft - Brooklyn Park MN
Thomas E. Hendrickson - Wayzata MN

Assignee:

Honeywell Inc. - Minneapolis MN

International Classification:

H01L 2704
H01L 2978

US Classification:

357 42

Abstract:

An IGFET is presented which includes a relatively low resistance path across the source-substrate junction to prevent parasitic bipolar effects while maintaining high component density in integrated circuits. The low resistance path across the source-substrate junction is formed by various methods including damaging the crystal structure at the junction interface, supplementing the damaged junction with a heavily doped region underlying the source region and spiking metallurgy. A particular application of the invention allows the prevention of latchup in CMOS devices. The invention also allows the source region of an IGFET to serve the dual functions of a source for a MOSFET as well as an ohmic contact to the underlying well or substrate.

US Patent:

42569796, Mar 17, 1981

Filed:

Dec 26, 1978

Appl. No.:

5/973463

Inventors:

Thomas E. Hendrickson - Wayzata MN
Thomas C. Spindler - Coon Rapids MN

Assignee:

Honeywell, Inc. - Minneapolis MN

International Classification:

H03K 1760
H01L 2972

US Classification:

307571

Abstract:

An electronic switching circuit is provided for controlling transfer of electrical power from an alternating polarity electrical power supply to a load means through use of a field-effect transistor device as the primary power controlling element.

US Patent:

42569770, Mar 17, 1981

Filed:

Dec 26, 1978

Appl. No.:

5/973215

Inventors:

Thomas E. Hendrickson - Wayzata MN

Assignee:

Honeywell Inc. - Minneapolis MN

International Classification:

H03K 1760
H01L 2972

US Classification:

307571

Abstract:

An electronic switching circuit is provided for controlling transfer of electrical power from an alternating polarity electrical power supply to a load means through use of a field-effect transistor device as the primary power controlling element.

US Patent:

42950570, Oct 13, 1981

Filed:

Nov 8, 1979

Appl. No.:

6/092785

Inventors:

Thomas E. Hendrickson - Wayzata MN

Assignee:

Honeywell Inc. - Minneapolis MN

International Classification:

H03K 522
H03K 500

US Classification:

307231

Abstract:

An electronic control circuit is provided which operates on selected characteristics of oppositely phased control signals. A logic arrangement sorts out those signal portions having the selected characteristics to provide an output signal.