Thomas R Herrin

Address:

635 Laurisa Ln, Antigo, WI 54409

Phone:

7156272350

VIN:

1G4HA5EM2BU123976

Make:

BUICK

Model:

LUCERNE

Year:

2011

US Patent:

6472529, Oct 29, 2002

Filed:

Apr 18, 2001

Appl. No.:

09/837280

Inventors:

Hing Leung Sham - Mundelein IL
Daniel W. Norbeck - Crystal Lake IL
Xiaoqi Chen - Libertyville IL
David A. Betebenner - Gurnee IL
Dale J. Kempf - Libertyville IL
Thomas R. Herrin - Waukegan IL
Gondi N. Kumar - Round Lake Beach IL
Stephen L. Condon - Kenosha WI
Arthur J. Cooper - Lake Villa IL
Daniel A. Dickman - Grayslake IL
Steven M. Hannick - Highland Park IL
Lawrence Kolaczkowski - Gurnee IL
Patricia A. Oliver - Lindenhurst IL
Daniel J. Plata - Waukegan IL
Peter J. Stengel - Waukegan IL
Eric J. Stoner - Kenosha WI
Jih-Hua Liu - Greek Oaks IL
Ketan M. Patel - Arlington Heights IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C07D23332

US Classification:

544316, 540488, 540492, 540531, 544 88, 544 97, 544332, 546220, 546243, 548229, 548233, 5483241, 5483315, 548550

Abstract:

A compound of the formula: is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

US Patent:

7279582, Oct 9, 2007

Filed:

Oct 25, 2002

Appl. No.:

10/280652

Inventors:

Eric J. Stoner - Kenosha WI, US
Arthur J. Cooper - Lake Villa IL, US
Lawrence Kolaczkowski - Gurnee IL, US
Ketan M. Patel - Arlington Heights IL, US
Hing Leung Sham - Mundelein IL, US
Daniel W. Norbeck - Crystal Lake IL, US
Xiaoqi Chen - Libertyville IL, US
David A. Betebenner - Gurnee IL, US
Thomas R. Herrin - Waukegan IL, US
Gondi N. Kumar - Round Lake Beach IL, US
Stephen L. Condon - Kenosha WI, US
Daniel A. Dickman - Grayslake IL, US
Patricia A. Oliver - Lindenhurst IL, US

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C07D 233/32
C07D 239/10
C07D 239/12

US Classification:

5483241, 540460, 540488, 540492, 544 88, 544 97, 544316, 544332, 548229, 548233, 5483315, 548550, 546233, 51421203, 514331, 514428

Abstract:

A compound of the formula:.

US Patent:

7968707, Jun 28, 2011

Filed:

Feb 27, 2007

Appl. No.:

11/679227

Inventors:

Hing Leung Sham - Mundelein IL, US
Daniel W. Norbeck - Crystal Lake IL, US
Xiaoqi Chen - Libertyville IL, US
David A. Betebenner - Gurnee IL, US
Dale J. Kempf - Libertyville IL, US
Thomas R. Herrin - Waukegan IL, US
Gondi N. Kumar - Round Lake Beach IL, US
Stephen L. Condon - Kenosha WI, US
Arthur J. Cooper - Lake Villa IL, US
Daniel A. Dickman - Grayslake IL, US
Steven M. Hannick - Highland Park IL, US
Lawrence Kolaczkowski - Gurnee IL, US
Patricia A. Oliver - Lindenhurst IL, US
Daniel J. Plata - Wads Worth IL, US
Peter J. Stengel - Waukegan IL, US
Eric J. Stoner - Kenosha WI, US
Jih-Hua Liu - Greek Oaks IL, US
Ketan M. Patel - Arlington Heights IL, US

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C07D 219/04
C07D 291/06
C07D 243/04
C07D 265/12
C07D 413/12
C07D 239/02

US Classification:

540488, 540492, 540460, 544 88, 544 97, 544316, 544332, 546233, 548229, 548233, 5483241, 5483315, 548550, 514218, 5142288, 514256, 514274, 514376, 514377, 514392, 51421203, 514331, 514428

Abstract:

A compound of the formula:.

US Patent:

45501637, Oct 29, 1985

Filed:

Jan 26, 1981

Appl. No.:

6/228414

Inventors:

Houston F. Voss - Libertyville IL
Jacob Plattner - Libertyville IL
Thomas R. Herrin - Waukegan IL

Assignee:

Abbott Laboratories - North Chicago IL

International Classification:

C07F 960
C07F 940

US Classification:

544244

Abstract:

The present invention encompasses a method for determining ligands in test samples comprising intermixing with the test sample a ligand analog-irreversible enzyme inhibitor conjugate and a binding protein bindable to the ligand and the ligand analog-irreversible enzyme inhibitor conjugate and wherein the amount of ligand analog-irreversible enzyme inhibitor conjugate bound by the binding protein is related to the amount of ligand in the test sample, said binding protein inactivating the irreversible enzyme inhibitor when bound to the ligand analog portion of the conjugate; intermixing an enzyme which is irreversibly inhibited by the ligand analog-irreversible enzyme inhibitor conjugate unbound by the binding protein; and intermixing substrate to the enzyme and monitoring the enzyme substrate reaction. The invention also includes ligand analog-irreversible enzyme inhibitor conjugates useful as reagents in practicing the method. Methods and reagents of the present are particularly useful in determining drugs, hormones, and the like in biological fluids.

US Patent:

63132966, Nov 6, 2001

Filed:

Feb 23, 2000

Appl. No.:

9/511390

Inventors:

Hing Leung Sham - Mundelein IL
Daniel W. Norbeck - Crystal Lake IL
Xiaoqi Chen - Libertyville IL
David A. Betebenner - Gurnee IL
Dale J. Kempf - Libertyville IL
Thomas R. Herrin - Waukegan IL
Gondi N. Kumar - Round Lake Beach IL
Stephen L. Condon - Kenosha WI
Arthur J. Cooper - Lake Villa IL
Daniel A. Dickman - Grayslake IL
Steven M. Hannick - Highland Park IL
Lawrence Kolaczkowski - Gurnee IL
Patricia A. Oliver - Lindenhurst IL
Daniel J. Plata - Waukegan IL
Peter J. Stengel - Waukegan IL
Eric J. Stoner - Kenosha WI
Jih-Hua Liu - Greek Oaks IL
Ketan M. Patel - Arlington Heights IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C07D23902
C07D24300
C07D23302

US Classification:

544315

Abstract:

A compound of the formula: ##STR1## is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

US Patent:

45434123, Sep 24, 1985

Filed:

Nov 4, 1983

Appl. No.:

6/548743

Inventors:

Charles A. Flentge - Lake Villa IL
Thomas R. Herrin - Waukegan IL

Assignee:

Abbott Laboratories - North Chicago IL

International Classification:

A61K 31675
A61K 3169
C07F 502
C07F 965

US Classification:

544229

Abstract:

Phenobarbital conjugates for use as enzyme inhibitors having the formula: ##STR1## wherein Z is a biologically compatible counter ion, n and m is an integer from 2 to 6 and R and R. sub. 1 are each lower alkyl.

US Patent:

62847678, Sep 4, 2001

Filed:

Dec 8, 1998

Appl. No.:

9/207873

Inventors:

Hing Leung Sham - Vernon Hills IL
Daniel W. Norbeck - Grayslake IL
Dale J. Kempf - Libertyville IL
Xiaoqi Chen - San Mateo CA
David A. Betebenner - Lawrenceville NJ
Thomas R. Herrin - Waukegan IL
Gondi N. Kumar - Newbury Park CA
John M. Lipari - Racine WI
Laman Alani - Morris Plains NJ
Soumojeet Ghosh - Lindenhurst IL
Rong R. Gao - Edison NJ
Dilip Kaul - Edison NJ

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 314166
A61K 31506
A61K 31535

US Classification:

514274

Abstract:

A compound of the formula: ##STR1## is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

US Patent:

39819825, Sep 21, 1976

Filed:

Sep 11, 1974

Appl. No.:

5/505185

Inventors:

Raymond Oslapas - Libertyville IL
Thomas Raymond Herrin - Waukegan IL

Assignee:

Abbott Laboratories - North Chicago IL

International Classification:

G01N 3300
G21H 502
C07J 1900

US Classification:

424 15

Abstract:

A competitive radioimmunoassay for the measurement of digoxin in a serum sample in which the non-radioactive digoxin competes with a constant amount of a radioactively labeled digoxin tyramine analog comprising 3-O-(4-Hydroxyphenethylcarbamoyl) digoxigenin for binding cites on a limited amount of digoxin antibody. The percentage of the radioactively labeled digoxin which is bound to the antibody is inversely proportional to the concentration of digoxin in the serum sample. The concentration of digoxin in the serum is determined by the comparison with standards containing measured amounts of unlabeled digoxin.