The present invention is directed to a method for treating dermal atrophy of the skin. The method of the invention includes applying a composition to the skin of a mammal suffering from dermal atrophy of the skin, and comprising at least one thyroid hormone compound or thyroid hormone-like compound together with a pharmacologically acceptable base suitable for topical application, wherein the thyroid hormone compound or the thyroid hormone-like compound binds to TR- or TR- with an equilibrium dissociation constant, K , of at least 10 M. The invention is also directed to an article of manufacture comprising packaging material and a pharmaceutical agent contained within the packaging material, wherein the pharmaceutical agent is therapeutically effective for treating dermal atrophy of the skin.
Treatment For Dermal Skin Atrophy Using Thyroid Hormone Compounds Or Thyroid Hormone-Like Compounds
The present invention is directed to a method for treating dermal atrophy of the skin. The method of the invention includes applying a composition to the skin of a mammal suffering from dermal atrophy of the skin, and comprising at least one thyroid hormone compound or thyroid hormone-like compound together with a pharmacologically acceptable base suitable for topical application, wherein the thyroid hormone compound or the thyroid hormone-like compound binds to TR- or TR- with an equilibrium dissociation constant, K, of at least 10M. The invention is also directed to an article of manufacture comprising packaging material and a pharmaceutical agent contained within the packaging material, wherein the pharmaceutical agent is therapeutically effective for treating dermal atrophy of the skin.
Treatment For Burns And Adipose Deposits Using Thyroid Hormone Compound In A Human
A topical preparation for treating first and second degree burns includes TriAc. The topical preparation preferably includes less than 10 mg of TriAc per 100 ml of pharmaceutical excipient base. In another embodiment, a topical preparation includes TriAc for decreasing cellulite. In this embodiment, the topical preparation is preferably applied only before exercise. In a preferred embodiment, the preparation is applied only intermittently, preferably no more than three times a week, or in amounts sufficient to not downregulate receptor number and become inefficacious.
Thomas Lavin - Watchung NJ, US Houssam Toutanji - Madison AL, US John Gilbert - Huntsville AL, US
Assignee:
OPTECHNOLOGY, INC. - Huntsville AL
International Classification:
C04B 26/04
US Classification:
524 4, 524 8
Abstract:
A method of improving the stress strain characteristics, the ductility, the energy absorbing characteristics, the fractal roughness and the material roughness of a cementitious mix includes adding at least 1%, by weight of the total weight of the cementitious mix of poly(vinyl butyrate) in addition to a reinforcing agent, preferably poly(vinyl alcohol). In a preferred embodiment, the amount of poly(vinyl butyrate) is about 40% to about 50%, by weight. This provides the optimum levels of performance of the characteristics listed above.
Thomas N. Lavin - Watchung NJ, US Catherine H. Koo - Watchung NJ, US
International Classification:
A61K 31/165 A61P 43/00
US Classification:
514618
Abstract:
A method for relieving, treating, improving or attenuating one or more symptoms of RLS and related movement disorders such as PLMS, and snoring ICSD 780.53-1 is disclosed. The method includes the administration to a host afflicted with RLS or related disorder a pharmaceutically effective amount of a modafinil compound or a related compound. The method of the present invention is to treat a host to reduce or diminish snoring, the unpleasant leg sensations associated with unwanted leg movements and to diminish or eliminate the unwanted, involuntary leg movements at rest, awake or asleep, typically occurring in the evenings and at night.
Treatments For Burns Using Thyroid Hormone Compound In A Human
A topical preparation for treating first and second degree burns includes TriAc. The topical preparation preferably includes less than 10 mg of TriAc per 100 ml of pharmaceutical excipient base. In another embodiment, a topical preparation includes TriAc for decreasing cellulite. In this embodiment, the topical preparation is preferably applied only before exercise. In a preferred embodiment, the preparation is applied only intermittently, preferably no more than three times a week, or in amounts sufficient to not downregulate receptor number and become inefficacious.
Allied-Signal Inc. - Morris Township, Morris County NJ
International Classification:
G01C 1968
US Classification:
356350
Abstract:
A pneumatically dithered ring laser gyroscope features providing an oscillatory motion directly to a segment of the excited gas which serves as the laser photon source. Alternately switching ionizing potential between two cathodes in appropriately designed cavities establishes desired oscillatory gas velocities to effect emitted frequencies within the gyro, thereby permitting the detection of rotational rates below the "lock-in" rate of the undithered gyro.
Uses For Thyroid Hormone Compounds Or Thyroid Hormone-Like Compounds
Thomas N. Lavin - Watchung NJ Anders B. Vahlquist - Uppsala, SE
Assignee:
Karo Bio AB - Huddinge
International Classification:
A61K 31195
US Classification:
514567
Abstract:
This invention relates to the use of topically applied thyroid hormone compounds and thyroid hormone-like compounds which are receptor binding ligands, either agonists or antagonists, to improve the appearance of the skin and underlying subcutaneous fat and improve certain medical conditions when applied topically. These compounds can be used to treat skin conditions such as stria, cellulite, roughened skin, actinic skin damage, intrinsically aged skin, photodamaged kin, lichen planus, ichthyosis, acne, psoriasis, wrinkled skin, corticosteroid atrophy, collagen deficient skin, and to diminish the size and improve the appearance of skin scarring from surgical or naturally occurring wounds, and to reduce the incidence of hyperkeratotic scarring. The thyroid agonists and antagonists may also promote differentiation and amelioration of dedifferentiated skin in premalignant lesions. The thyroid agonists and antagonists can be active in all organisms which contain the thyroid hormone receptors, notably amphibians, birds and subjects.
Surgical Specialists Of Louisiana 7015 Hwy 190 E Ser Rd STE 200, Covington, LA 70433 9852343000 (phone), 9852343001 (fax)
Education:
Medical School University of Toledo College of Medicine Graduated: 1988
Procedures:
Bariatric Surgery Hernia Repair Laparoscopic Gallbladder Removal Upper Gastrointestinal Endoscopy Appendectomy Laparoscopic Appendectomy Small Bowel Resection Spleen Surgey Thoracoscopy
Conditions:
Abdominal Hernia Appendicitis Breast Disorders Cholelethiasis or Cholecystitis Femoral Hernia
Languages:
English
Description:
Dr. Lavin graduated from the University of Toledo College of Medicine in 1988. He works in Covington, LA and specializes in General Surgery and Bariatrician. Dr. Lavin is affiliated with Fairway Medical Surgical Hospital.
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