Thomas Michael Loftus - Great Falls VA, US Dorian Sergio Araneda - Lovettesville VA, US James Robert Sherman - Penn Laird VA, US
Assignee:
Blackbird Technologies, Inc. - Herndon VA
International Classification:
G01C 21/30
US Classification:
701208, 701207, 701213, 34053913
Abstract:
A handheld device and system includes a mapping module, a tracking module interoperative with the mapping module, and a communications module interoperative with the tracking module and the mapping module. At least two antennae are communicatively connected, via the communications module, to at least one central processing unit. At least one of said at least two antenna is suitable for communicating using at least two distinct communication modes.
Mobile Unit And System Having Integrated Mapping, Communications And Tracking
Thomas Michael Loftus - Great Falls VA, US Dorian Sergio Araneda - Lovettesville VA, US James Robert Sherman - Penn Laird VA, US
Assignee:
Blackbird Technologies, Inc. - Herndon VA
International Classification:
G01C 21/30
US Classification:
701208, 701207, 701213, 34053913
Abstract:
A handheld device and system, in which such device and system include at least one mapping module, at least one tracking module interoperative with said at least one mapping module, at least one communications module interoperative with each of said at least one tracking module and said at least one mapping module, at least two antennae communicatively connected via said at least one communications module to at least one central processing unit, wherein at least one of said at least two antenna is suitable for communications using at least two distinct communication modes.
Weight Loss Induced By Reduction In Neuropeptide Y Level
Thomas Loftus - Great Falls VA, US Craig Townsend - Baltimore MD, US Gabriele Ronnett - Lutherville MD, US M. Lane - Baltimore MD, US Francis Kuhajda - Lutherville MD, US
International Classification:
A61K031/365
US Classification:
514/473000
Abstract:
This invention provides a method for inducing weight loss in an animal by administering to the animal a compound which reduces the expression and/or secretion of neuropeptide Y (NPY). The effect may be accomplished directly, indirectly or humorally. Preferably, administration of this compound has the effect of increasing malonyl CoA levels in the animal. Compounds administered according to this invention may be inhibitors of fatty acid synthase (FAS), including substituted -methylene--carboxyl--butyrolactones, or inhibitors of malonyl Coenzyme A decarboxylase (MCD). Preferably, the compound is administered in an amount sufficient to reduce the amount and/or duration of expression and/or secretion of NPY to levels at or below those observed for lean animals. In another preferred embodiment, the administration will reduce expression and/or secretion to levels observed for fed or satiated animals; more preferably, administration will reduce the level of NPY below that of fed animals. In a particular embodiment, this invention provides a method for inducing weight loss in an animal by administering a compound which inhibits feeding behavior in the animal. The method is particularly useful for inducing weight loss in animals deficient in expression of the hormone leptin or animals resistant to the action of leptin.
Weight Loss Induced By Reduction In Neuropeptide Level
Thomas Loftus - Great Falls VA, US Craig Townsend - Baltimore MD, US Gabrielle Ronnett - Lutherville MD, US M. Lane - Baltimore MD, US Francis Kuhajda - Lutherville MD, US
Assignee:
The Johns Hopkins University School of Medicine Licensing and Technology Development - Baltimore MD
International Classification:
A61K 31/365 C12Q 1/68
US Classification:
514473000, 435006000
Abstract:
This invention provides a method for inducing weight loss in an animal by administering to the animal a compound which reduces the expression and/or secretion of neuropeptide Y (NPY). The effect may be accomplished directly, indirectly, or humorally. Preferably, administration of this compound has the effect of increasing malonyl CoA levels in the animal. Compounds administered according to this invention may be inhibitors of fatty acid synthase (FAS), including substituted α-methylene-β-carboxyl-γ-butyrolactones, or inhibitors of malonyl Coenzyme A decarboxylase (MCD). Preferably, the compound is administered in an amount sufficient to reduce the amount and/or duration of expression and/or secretion of NPY to levels at or below those observed for lean animals. In another preferred embodiment, the administration will reduce expression and/or secretion to levels observed for fed or satiated animals; more preferably, administration will reduce the level of NPY below that of fed animals. In a particular embodiment, this invention provides a method for inducing weight loss in an animal by administering a compound which inhibits feeding behavior in the animal. The method is particularly useful for inducing weight loss in animals deficient in expression of the hormone leptin or animals resistant to the action of leptin.
Thomas M. Loftus - Great Falls VA, US Craig A. Townsend - Baltimore MD, US Gabriele Ronnett - Lutherville MD, US M. Daniel Lane - Baltimore MD, US Francis P. Kuhajda - Lutherville MD, US
Assignee:
The Johns Hopkins University School of Medicine Licensing and Technology Development - Baltimore MD
International Classification:
A61K 31/365 C12Q 1/68 A61K 31/336
US Classification:
514473, 435 6, 514475
Abstract:
This invention provides a method for inducing weight loss in an animal by administering to the animal a compound which reduces the expression and/or secretion of neuropeptide Y (NPY). The effect may be accomplished directly, indirectly, or humorally. Preferably, administration of this compound has the effect of increasing malonyl CoA levels in the animal. Compounds administered according to this invention may be inhibitors of fatty acid synthase (FAS), including substituted α-methylene-β-carboxyl-γ-butyrolactones, or inhibitors of malonyl Coenzyme A decarboxylase (MCD). Preferably, the compound is administered in an amount sufficient to reduce the amount and/or duration of expression and/or secretion of NPY to levels at or below those observed for lean animals. In another preferred embodiment, the administration will reduce expression and/or secretion to levels observed for fed or satiated animals; more preferably, administration will reduce the level of NPY below that of fed animals. In a particular embodiment, this invention provides a method for inducing weight loss in an animal by administering a compound which inhibits feeding behavior in the animal. The method is particularly useful for inducing weight loss in animals deficient in expression of the hormone leptin or animals resistant to the action of leptin.
Mobile Unit And System Having Integrated Mapping, Communications And Tracking
Thomas Michael Loftus - Great Falls VA, US Dorian Sergio Araneda - Lovettesville VA, US James Robert Sherman - Penn Laird VA, US
Assignee:
Blackbird Technologies, Inc. - Herndon VA
International Classification:
G01C 21/30 G08B 1/08
US Classification:
701409, 34053913
Abstract:
A handheld device and system, in which such device and system include at least one mapping module, at least one tracking module interoperative with said at least one mapping module, at least one communications module interoperative with each of said at least one tracking module and said at least one mapping module, at least two antennae communicatively connected via said at least one communications module to at least one central processing unit, wherein at least one of said at least two antenna is suitable for communications using at least two distinct to communication modes.
- Sunnyvale CA, US Adam T. Black - Annandale VA, US Thang Q. Tran - San Jose CA, US Matthew D. Swallows - Santa Clara CA, US Brian R. Patton - San Francisco CA, US Miao Zhu - San Jose CA, US Thomas H. Loftus - Arvada CO, US Mark A. Kasevich - Palo Alto CA, US
International Classification:
G04F 5/14 H03L 7/26 H05H 3/02
Abstract:
An atomic oscillator device includes an atomic oscillator, a controlled oscillator, a resonance controller, and a cold-atom clock output. The atomic oscillator comprises a two-dimensional optical cooling region (2D OCR) for providing a source of atoms and a three-dimensional optical cooling region (3D OCR) for cooling and/or trapping the atoms emitted by the 2D OCR. The atomic oscillator comprises a microwave cavity surrounding the 3D OCR for exciting an atomic resonance. The controlled oscillator produces an output frequency. The resonance controller is for steering the output frequency of the controlled oscillator based on the output frequency and the atomic resonance as measured using an atomic resonance measurement. The cold-atom clock output is configured as being the output frequency of the controlled oscillator.
2012 to 2000 Senior Railway Financial ExpertSENECA GROUP, LLC Washington, DC 2009 to 2012SENECA GROUP, LLC
2009 to 2012 Principal/ConsultantVECTORA TRANSPORTATION Chicago, IL 2008 to 2009 Chief Financial OfficerCENTRAL ILLINOIS RAILROAD HOLDINGS, LLC Rochelle, IL 2007 to 2008 Chief Financial OfficerSeneca Group Washington, DC 2005 to 2006Seneca Group
2005 to 2006 Contract ConsultantGENESEE & WYOMING INC
2000 to 2005 Sr. Vice President, Finance and TreasurerGENESEE & WYOMING INC Greenwich, CT 1996 to 2005GENESEE & WYOMING INC
1996 to 2000 Vice President FinanceRAILTEX, INC
1995 to 1996 ManagerRAILTEX, INC San Antonio, TX 1993 to 1996RAILTEX, INC
1993 to 1996 Manager Financial Planning and Analysis
Education:
University of Pittsburgh 1984 Masters of Business Administration in FinanceUniversity of Virginia 1981 Bachelor of Arts in English
Jul 2008 to May 2011 Senior Vice President, Business & Legal AffairsTHE WEINSTEIN COMPANY Los Angeles, CA May 2007 to Jul 2008 Vice President, Business & Legal AffairsDIC ENTERTAINMENT, INC
Oct 2006 to May 2007 Senior Director, Business & Legal AffairsWALT DISNEY COMPANY
Sep 2001 to Sep 2006 Business & Legal Affairs Features Senior CounselGORDON & REES Los Angeles, CA Aug 1999 to Sep 2001 Litigation AssociateIVERSON, YOAKUM, PAPIANO & HATCH Los Angeles, CA Jan 1998 to Aug 1999 Litigation Associate
Education:
Loyola Law School Los Angeles, CA Jan 1997 J.D.
Name / Title
Company / Classification
Phones & Addresses
Thomas L. Loftus Owner
Toms Tinker Maintenance Misc Personal Services
6870 Via Kannela, Stanton, CA 90680
Thomas S. Loftus Director
Neurodiagnostics & Neuromonitoring Institute, Inc
Thomas R. Loftus Principal
Tom Loftus Tax Services Tax Return Preparation Services
8710 Falkstone Ln, Alexandria, VA 22309
Thomas Loftus
ALISO AIR CONDITIONING & HEATING Heating & Air Conditioning/hvac
29736 Avenida De Las Bndra, Rancho Santa Margarita, CA 92688 9493482204
Thomas Loftus Director
Sacred Heart of Jesus Church Religious Organization
Austin Neurosurgical Institute 2200 Park Bnd Dr STE 202, Austin, TX 78758 5128360900 (phone), 5128360902 (fax)
Education:
Medical School University of Texas Southwestern Medical Center at Dallas Graduated: 1997
Procedures:
Carpal Tunnel Decompression Spinal Cord Surgery Spinal Fusion Spinal Surgery Craniotomy Lumbar Puncture
Conditions:
Intervertebral Disc Degeneration
Languages:
English
Description:
Dr. Loftus graduated from the University of Texas Southwestern Medical Center at Dallas in 1997. He works in Austin, TX and specializes in Surgery , Neurological. Dr. Loftus is affiliated with Hospital At Westlake Medical Center, Northwest Hills Surgical Hospital and St Davids North Austin Medical Center.