Thomas Claiborne Lovelace

US Patent:

20040026230, Feb 12, 2004

Filed:

Apr 23, 2003

Appl. No.:

10/399809

Inventors:

Roman Davis - Durham NC, US
Thomas Lovelace - Durham NC, US

International Classification:

C07D487/02

US Classification:

204/157700, 204/157710

Abstract:

The invention describes a method for effecting intramolecular cyclization reactions using light, in the absence of radical initiators, to provide useful polycyclic compounds.

US Patent:

20200216408, Jul 9, 2020

Filed:

Mar 4, 2020

Appl. No.:

16/808871

Inventors:

- Cary NC, US
Christopher L. Larson - Cary NC, US
Mark T. Singleton - Morris CT, US
Kamal L. Kataria - Maharashtra State, IN
Samantha Besse - Daban, FR
Thomas C. Lovelace - Apex NC, US
Chandra S. Kanugala - Telangana, IN
Srinivas Vollala - Telangana, IN
Balraju Vadla - Telangana, IN

International Classification:

C07D 341/00
A01N 43/32
A01N 43/80

Abstract:

A method for manufacturing an insecticidal compound and insecticidal compositions comprising the insecticidal compound and methods of use are presented herein. The manufacturing method presented herein allows for a high purity grade of thiocyclam hydrochloride to be synthesized. The insecticidal compositions comprising the thiocyclam hydrochloride can be used for prevention of crop destruction by insects. The use of thiocyclam hydrochloride in insecticidal compositions as described herein can achieve greater efficacy than previously known insecticides, by eliminating the insect pests more reliably and efficiently.

US Patent:

20200216409, Jul 9, 2020

Filed:

Mar 4, 2020

Appl. No.:

16/808905

Inventors:

- Cary NC, US
Christopher L. Larson - Cary NC, US
Mark T. Singleton - Morris CT, US
Kamal L. Kataria - Maharashtra State, IN
Samantha Besse - Daban, FR
Thomas C. Lovelace - Apex NC, US
Chandra S. Kanugala - Telangana, IN
Srinivas Vollala - Telangana, IN
Balraju Vadla - Telangana, IN

International Classification:

C07D 341/00
A01N 43/32
A01N 43/80

Abstract:

A method for manufacturing an insecticidal compound and insecticidal compositions comprising the insecticidal compound and methods of use are presented herein. The manufacturing method presented herein allows for a high purity grade of thiocyclam hydrochloride to be synthesized. The insecticidal compositions comprising the thiocyclam hydrochloride can be used for prevention of crop destruction by insects. The use of thiocyclam hydrochloride in insecticidal compositions as described herein can achieve greater efficacy than previously known insecticides, by eliminating the insect pests more reliably and efficiently.

US Patent:

20200023003, Jan 23, 2020

Filed:

Jul 1, 2019

Appl. No.:

16/458267

Inventors:

- Research Triangle Park NC, US
Thomas Claiborne LOVELACE - Apex NC, US
Daniel Logan KIRSCHNER - Raleigh NC, US

International Classification:

A61K 33/04
A61K 47/02
A61K 47/18
A61K 9/08
A61K 9/00

Abstract:

Described herein is anhydrous sodium thiosulfate, methods for synthesizing anhydrous sodium thiosulfate, pharmaceutical compositions thereof, and methods of treating ototoxicity. Anhydrous sodium thiosulfate is synthesized from sodium sulfite, sulfur, and cetylpyridinium chloride. The anhydrous sodium thiosulfate is formulated into a pharmaceutical composition comprising a buffer and solvent. These compositions are useful for eliminating or reducing ototoxicity in pediatric patients receiving platinum based chemotherapeutics.

US Patent:

20180079739, Mar 22, 2018

Filed:

Sep 19, 2016

Appl. No.:

15/268734

Inventors:

- Cary NC, US
Christopher L. Larson - Cary NC, US
Mark T. Singleton - Morris CT, US
Kamal L. Kataria - Maharashtra State, IN
Samantha Besse - Daban, FR
Thomas C. Lovelace - Apex NC, US
Chandra S. Kanugala - Telangana, IN
Srinivas Vollala - Telangana, IN
Balraju Vadla - Telangana, IN

International Classification:

C07D 341/00
A01N 43/32
A01N 43/80

Abstract:

A method for manufacturing an insecticidal compound and insecticidal compositions comprising the insecticidal compound and methods of use are presented herein. The manufacturing method presented herein allows for a high purity grade of thiocyclam hydrochloride to be synthesized. The insecticidal compositions comprising the thiocyclam hydrochloride can be used for prevention of crop destruction by insects. The use of thiocyclam hydrochloride in insecticidal compositions as described herein can achieve greater efficacy than previously known insecticides, by eliminating the insect pests more reliably and efficiently.