Michael S. Strano - Lexington MA, US Paul W. Barone - Jamaica Plain MA, US Jin-Ho Ahn - Seoul, KR Kyungsuk Yum - Berkeley CA, US Thomas P. McNicholas - Cambridge MA, US
International Classification:
A61B 5/1459 B82Y 15/00
US Classification:
600316, 977742, 977750
Abstract:
A composition for sensing an analyte can include a photoluminescent nanostructure complexed to a sensing polymer, where the sensing polymer includes an organic polymer non-covalently bound to the photoluminescent nanostructure and an analyte-binding protein covalently bound to the organic polymer, and where the analyte-binding protein is capable of selectively binding the analyte, and the analyte-binding protein undergoes a substantial conformational change when binding the analyte. Separately, a composition for sensing an analyte, can include a complex, where the complex includes a photoluminescent nanostructure in an aqueous surfactant dispersion and a boronic acid capable of selectively reacting with an analyte. The compositions can be used in devices and methods for sensing an analyte.
Near Infrared Fluorescent Single Walled Carbon Nanotubes As Tissue Localizable Biosensors
- Cambridge MA, US Michael S. Strano - Lexington MA, US Nigel F. Reuel - Cambridge MA, US Thomas P. McNicholas - Cambridge MA, US
International Classification:
A61B 5/1455 A61B 5/145 A61B 5/1459
US Classification:
600316, 600317, 427 74
Abstract:
A nanosensor for detecting an analyte can include a substrate, a photoluminescent nanostructure, and a polymer interacting with the photoluminescent nanostructure. The nanosensor can be used in in vivo for biomedical applications.
Name / Title
Company / Classification
Phones & Addresses
Thomas Mcnicholas
C-TONIC CORP
261 Lakeview Ave, Rockville Centre, NY 11570 44 Tioga Walk, Breezy Point, NY 11697