Thomas E Myers

US Patent:

6346379, Feb 12, 2002

Filed:

Sep 3, 1998

Appl. No.:

09/146631

Inventors:

David Harrow Gelfand - Oakland CA
Lisa Vivian Kalman - San Francisco CA
Fred Lawrence Reichert - Oakland CA
Christopher Lim Sigua - Antioch CA
Thomas W. Myers - Alameda CA

Assignee:

F. Hoffman-La Roche AG - Basel

International Classification:

C12Q 168

US Classification:

435 6, 435 911, 530300, 530327, 536 231, 536 232

Abstract:

Modified thermostable DNA polymerases having enhanced efficiency for incorporating unconventional nucleotides such as those labeled with fluorescein family dyes are advantageous in many in vitro DNA synthesis applications. Such enzymes are particularly useful for use in chain termination nucleic acid sequencing protocols, as are native forms of such enzymes. Genes encoding the modified enzymes and methods for their production and use offer cost and efficiency advantages for DNA sequencing.

US Patent:

6668106, Dec 23, 2003

Filed:

Feb 23, 2001

Appl. No.:

09/792287

Inventors:

Jules D. Levine - Santa Clara CA
Thomas W. Myers - Sunnyvale CA
Christopher Weller - Sunnyvale CA

Assignee:

Teraburst Networks, Inc. - Sunnyvale CA

International Classification:

G02B 626

US Classification:

385 16, 385 17, 385 24, 385 40, 333113, 333114, 333 21 R, 398 45, 398 50, 398 56, 398 82, 398 83

Abstract:

The present invention combines several features to create a novel type of optical telecommunications switching component using microwave waveguides as opposed to the usual methods employing light deflection or digital signal processing. Some of the components of the device include: (1) an optical crossconnect (OXC) which allows any combination of wavelengths to be added or dropped from an element to an optical network, (2) an optical add/drop multiplexer (OADM) which allows any wavelength to be converted to any other, (3) a microwave crossbar switch array optimized for this purpose, and (4) a means for reshaping the exiting signal from the microwave crosspoint switch array without regard to signal format and without need for complex and expensive digital signal processing. The minimal architecture for this functionality is shown to be three NÃN microwave crossbar switch arrays.

US Patent:

6877049, Apr 5, 2005

Filed:

May 30, 2002

Appl. No.:

10/161470

Inventors:

Thomas Andrew Myers - San Jose CA, US

Assignee:

Finisar Corporation - Sunnyvale CA

International Classification:

G06F003/00

US Classification:

710 56, 710 52, 710 53, 710 54, 710 55, 710 57

Abstract:

An integrated data controller that utilizes a first-in first-out (FIFO) management system that compensates for the unpredictable nature of latency associated with requesting data from memory and enables the timing of data requests to be determined based on the number of pending requests and the amount of data currently residing in the buffer. The FIFO management system includes a FIFO controller and a FIFO buffer that monitor a credit value and a trigger value to determine when to make data request bursts upon a memory unit. The trigger value is an indication of whether there is a sufficient amount of free space for it to be beneficial to make a data request burst and the credit value is a number that indicates the number of a data blocks that should be requested in the data request burst.

US Patent:

7148049, Dec 12, 2006

Filed:

Mar 26, 2003

Appl. No.:

10/401403

Inventors:

Nancy J. Schoenbrunner - Moraga CA, US
Thomas W. Myers - Alameda CA, US
David H. Gelfand - Oakland CA, US

Assignee:

Roche Molecular Systems, Inc. - Alameda CA

International Classification:

C12N 9/12

US Classification:

435194, 435196

Abstract:

The present invention provides thermostable or thermoactive DNA polymerases with attenuated 3′-5′ exonuclease activity, methods for their synthesis, methods for their use, kits comprising the polymerases, nucleic acids encoding the polymerases and cells comprising such a nucleic acid. The DNA polymerases of the invention are useful in many recombinant DNA techniques, such as nucleic acid amplification by the polymerase chain reaction. The DNA polymerases of the invention allow higher fidelity replication and amplification of a template DNA sequence, allow less degradation of primers and/or more efficient use of deoxynucleotide triphosphates and are in general more efficient and less costly to make and use.

US Patent:

7179590, Feb 20, 2007

Filed:

Mar 30, 2001

Appl. No.:

09/823649

Inventors:

Edward Soh Smith - San Francisco CA, US
Carita Maria Elfstrom - San Francisco CA, US
David Harrow Gelfand - Oakland CA, US
Russell Gene Higuchi - Alameda CA, US
Thomas William Myers - Alameda CA, US
Alice Ming Wang - Lafayette CA, US

Assignee:

Roche Molecular Systems, Inc - Alameda CA

International Classification:

C07H 21/04
C12Q 1/68

US Classification:

435 6, 435 911, 435 912, 435 9121, 536 231

Abstract:

The present invention relates to improved reverse transcription methods using a modified thermostable DNA polymerases, particularly in a magnesium ion buffer. These methods are particularly useful in combined reverse-transcription/amplification reactions.

US Patent:

7206831, Apr 17, 2007

Filed:

Aug 26, 2002

Appl. No.:

10/228212

Inventors:

Jean-François Dubé - Santa Clara CA, US
Thomas A. Myers - San Jose CA, US
Douglas Durham - Sunnyvale CA, US
Andrew J. Milne - Sierra Madre CA, US
Roumel R. Garcia - Vallejo CA, US
A. Michael Lawson - Morgan Hill CA, US

Assignee:

Finisar Corporation - Sunnyvale CA

International Classification:

G06F 15/16

US Classification:

709223, 224230, 712228, 370254

Abstract:

A programmable data filtering/searching system for use with a data network. The primary programmable hardware-based filtering and searching portions of the system are integrated onto the same printed circuit board as the data storage device to facilitate efficient filtering and searching of data from a data stream coming from a memory storage device after being captured. In addition, the actual hardware and software used to perform the filtering and searching routines is programmable such that various filter and search criteria can be entered and utilized. The data filtering/searching system also uses metadata in addition to the captured data to minimize the time required to perform certain processes on the data from the data stream.

US Patent:

7282060, Oct 16, 2007

Filed:

Dec 21, 2004

Appl. No.:

11/020648

Inventors:

Leonard C DeBenedictis - Palo Alto CA, US
Thomas R Myers - Palo Alto CA, US
Kin F Chan - San Jose CA, US
George Frangineas, Jr. - Fremont CA, US

Assignee:

Reliant Technologies, Inc. - Mountain View CA

International Classification:

A61N 5/06

US Classification:

607 88, 128898, 606 9

Abstract:

The present invention provides methods and apparatus for controlling light-induced tissue treatment. In accordance with various aspects of the present invention, the invention provides for improved, real-time control of the light beam operational parameters which enables greater safety, efficiency, uniformity and continuity of the treatment process.

US Patent:

7546451, Jun 9, 2009

Filed:

Jun 19, 2002

Appl. No.:

10/174621

Inventors:

Chris Cicchetti - Menlo Park CA, US
Jean-François Dubé - Santa Clara CA, US
Thomas Andrew Myers - San Jose CA, US
An Huynh - Alameda CA, US
Geoffrey T. Hibbert - San Jose CA, US

Assignee:

Finisar Corporation - Sunnyvale CA

International Classification:

G06F 9/00

US Classification:

713100, 713 1, 713 2, 711 2, 711 5, 712206

Abstract:

A system and method for enabling a programmable device to execute instructions without interruption. An instruction space for storing instructions from a host application is bifurcated to define a program segment and a hold segment. At startup, instructions are loaded into the hold segment, and the programmable device begins executing those instructions. While the hold segment instructions are executed, the program segment is loaded with instructions. Once the program segment is filled, control is shifted to it and instructions from this segment are executed by the programmable device. When the program segment has been executed, control is shifted back to the hold segment, and instructions are taken from it while the program segment is reloaded with a fresh set of instructions from the host application. Once the program segment is reloaded, control is redirected and execution of instructions from the program segment is continued.