Thomas L Pollock

US Patent:

6355776, Mar 12, 2002

Filed:

Nov 22, 1999

Appl. No.:

09/444791

Inventors:

Franco A. Ferrari - La Jolla CA
Charles Richardson - Florence MT
James Chambers - San Diego CA
Stuart Causey - Palo Alto CA
Thomas J. Pollock - San Diego CA
Joseph Cappello - San Diego CA
John W. Crissman - San Diego CA

Assignee:

Protein Polymer Technologies, Inc. - San Diego CA

International Classification:

C07K 1300

US Classification:

530350

Abstract:

Novel polypeptides comprising repetitive units of amino acids, as well as synthetic genes encoding the subject polypeptides are provided. The subject polypeptides are characterized by comprising repetitive units of amino acids, where the repetitive units are present in naturally occurring proteins, particularly naturally occurring structural proteins. The subject polypeptides find use in a variety of applications, such as structural components of prosthetic devices, synthetic fibers, and the like.

US Patent:

20030083464, May 1, 2003

Filed:

Mar 12, 2002

Appl. No.:

10/096986

Inventors:

Franco Ferrari - La Jolla CA, US
Charles Richardson - Florence MT, US
James Chambers - Encinitas CA, US
Stuart Causey - Palo Alto CA, US
Thomas Pollock - San Diego CA, US
Joseph Cappello - San Diego CA, US
John Crissman - San Diego CA, US

Assignee:

Protein Polymer Technologies, Inc.

International Classification:

C07K014/435

US Classification:

530/350000, 530/324000

Abstract:

Novel polypeptides comprising repetitive units of amino acids, as well as synthetic genes encoding the subject polypeptides are provided. The subject polypeptides are characterized by comprising repetitive units of amino acids, where the repetitive units are present in naturally occurring proteins, particularly naturally occurring structural proteins. The subject polypeptides find use in a variety of applications, such as structural components of prosthetic devices, synthetic fibers, and the like.

US Patent:

53548175, Oct 11, 1994

Filed:

Apr 20, 1992

Appl. No.:

7/870953

Inventors:

Masahiro Usuki - Ibaraki, JP
Hajime Kitamura - Chiba, JP
Susumu Ueno - Ibaraki, JP
Mikio Watanabe - Ibaraki, JP
Richard W. Armentrout - La Jolla CA
Thomas J. Pollock - San Diego CA

Assignee:

Shin-Etsu Chemical Co., Ltd. - Tokyo

International Classification:

C08F 200

US Classification:

526 62

Abstract:

A polymer scale preventive agent for use in polymerization of a haloethylene or a monomer mixture containing the same, comprising: (A) an aromatic compound having at least one group selected from the class consisting of primary, secondary and tertiary amino groups, quaternary ammonium groups and the azo group and/or a dye having at least one group selected from said class, and (B) an alkali metal or ammonium salt of a polyvinylsulfonic acid, and (C) a naphthoquinone natural dye; a polymerization vessel having a coating comprising said scale preventive agnet. A process of preparing a haloethylene polymer using the vessel can produce a polymer of high quality without polymer scale deposition.

US Patent:

54016592, Mar 28, 1995

Filed:

May 31, 1994

Appl. No.:

8/251600

Inventors:

Linda P. Thorne - Palomar CA
Richard W. Armentrout - La Jolla CA
Thomas J. Pollock - San Diego CA
Marcia J. Mikolajczak - Encinitas CA

Assignee:

Shin-Etsu Bio, Inc. - San Diego CA
Shin-Etsu Chemical Co., Ltd. - Tokyo

International Classification:

C12N 924
C12N 120
C12N 100
C12P 1914

US Classification:

4352525

Abstract:

An isolated endogly canase having activity against polysaccharides having the subunit backbone structure: ##STR1## wherein Glc is glucose, GlcA is glucuronic acid, Rha is rhamnose, Man is mannose, X may be Rha or Man, and wherein the reducing end of the polymer is toward the X residue of the backbone is disclosed. A method for producing the compound by culturing Bacillus ATCC 55294, the method for selecting Bacillus ATCC 55294 and method for using the endoglycanase are also disclosed.

US Patent:

60180307, Jan 25, 2000

Filed:

Jun 7, 1995

Appl. No.:

8/482085

Inventors:

Franco A. Ferrari - La Jolla CA
Charles Richardson - Florence MT
James Chambers - San Diego CA
Stuart Causey - Palo Alto CA
Thomas J. Pollock - San Diego CA
Joseph Cappello - San Diego CA
John W. Crissman - San Diego CA

Assignee:

Protein Polymer Technologies, Inc. - San Diego CA

International Classification:

A61K 3817
C12N 500
C07H 2104

US Classification:

530353

Abstract:

Polypeptides comprising repetitive units of amino acids, as well as synthetic genes encoding the subject polypeptides are provided. The subject polypeptides are characterized by comprising repetitive units of amino acids, where the repetitive units are present in naturally occurring proteins, particularly naturally occurring structural proteins. The subject polypeptides find use in a variety of applications, such as structural components of prosthetic devices, synthetic fibers, and the like.

US Patent:

52430383, Sep 7, 1993

Filed:

Oct 29, 1987

Appl. No.:

7/114618

Inventors:

Franco A. Ferrari - La Jolla CA
Charles Richardson - San Diego CA
James Chambers - San Diego CA
Stuart C. Causey - Del Mar CA
Thomas J. Pollock - San Diego CA
Joseph Capello - San Diego CA
John W. Crissman - San Diego CA

Assignee:

Protein Polymer Technologies, Inc. - San Diego CA

International Classification:

C12N 1511
C12N 1562
C07K 1300

US Classification:

536 231

Abstract:

Methods are provided for the production of large polypeptides containing repeating sequences of amino acids utilizing biochemical techniques, specifically DNA sequences coding for the expression of the large polypeptides. Systems utilizing exogenous transcriptional and translational regions to control the production of the large polypeptides are also provided.

US Patent:

57706972, Jun 23, 1998

Filed:

Jun 7, 1995

Appl. No.:

8/477509

Inventors:

Franco A. Ferrari - La Jolla CA
Charles Richardson - Florence MT
James Chambers - San Diego CA
Stuart Causey - Palo Alto CA
Thomas J. Pollock - San Diego CA
Joseph Cappello - San Diego CA
John W. Crissman - San Diego CA

Assignee:

Protein Polymer Technologies, Inc. - San Diego CA

International Classification:

A61K 3817
A61K 3839
C12P 2102

US Classification:

530353

Abstract:

Novel polypeptides comprising repetitive units of amino acids, as well as synthetic genes encoding the subject polypeptides are provided. The subject polypeptides are characterized by comprising repetitive units of amino acids, where the repetitive units are present in naturally occurring proteins, particularly naturally occurring structural proteins. The subject polypeptides find use in a variety of applications, such as structural components of prosthetic devices, synthetic fibers, and the like.

US Patent:

53427734, Aug 30, 1994

Filed:

Feb 11, 1993

Appl. No.:

8/016357

Inventors:

Linda P. Thorne - Palomar CA
Richard W. Armentrout - La Jolla CA
Thomas J. Pollock - San Diego CA
Marcia J. Mikolajczak - Encinitas CA

Assignee:

Shin-Etsu Bio, Inc. - San Diego CA
Shin-Etsu Chemical Co., Ltd. - Tokyo

International Classification:

C12N 924
C12N 120
C12N 100

US Classification:

435200

Abstract:

An isolated endoglycanase having activity against polysaccharides having the subunit backbone structure: ##STR1## wherein Glc is glucose, GlcA is glucuronic acid, Rha is rhamnose, Man is mannose, X may be Rha or Man, and wherein the reducing end of the polymer is toward the X residue of the backbone is disclosed. A method for producing the endoglycanase by culturing Bacillus ATCC 55294, the method for selecting the Bacillus ATCC 55294 and method for using the endoglycanase are also disclosed. The endoglycanase has a molecular weight of 110,000. +-. 10,000 daltons and a pH range from 4. 5 to 9.