Thomas F Richardson

US Patent:

20030022856, Jan 30, 2003

Filed:

Jan 30, 2002

Appl. No.:

10/058835

Inventors:

Thomas Richardson - Ann Arbor MI, US
David Mooney - Ann Arbor MI, US

Assignee:

The Regents Of The University of Michigan - Ann Arbor MI

International Classification:

A61K048/00
A61K038/19
A61K038/17
A61K031/704
A61K031/7072
A61K031/525
A61K009/14

US Classification:

514/044000, 514/012000, 424/085100, 514/251000, 514/050000, 514/033000, 424/486000

Abstract:

Described herein are methods for ablation, i.e., elimination or reduction, of unwanted tissue, particularly tissue which is normal to be present in the body but is unwanted for either health or cosmetic reasons. In particular embodiments, there are described methods for elimination of fat tissue from the body. According to the methods described herein, a drug which acts to eliminate the undesired tissue is provided in a carrier which is biocompatible, capable of being administered by injection, and which effects a controlled release of the drug over time. The drug with carrier is administered by injection locally in the area of the unwanted tissue, resulting in elimination of the tissue in that local area.

US Patent:

52338673, Aug 10, 1993

Filed:

Oct 30, 1992

Appl. No.:

7/969046

Inventors:

Thomas W. Richardson - Waterford MI
Robert G. Malcolm - Waterford MI

International Classification:

G01C 2110

US Classification:

73186

Abstract:

A dynamic fluid flow measurement apparatus is intended to be connected to a relative reference member, such as a marine vessel. The apparatus preferably includes a base member, a lever mechanism movable relative to the base member for transmitting force corresponding to direct dynamic fluid flow pressure applied to the lever mechanism, and a signal generator disposed in the base member for actuation by the lever mechanism. The signal generator generates an output signal corresponding to the force transmitted through the lever mechanism in response to fluid flow passed the relative reference member. In the preferred embodiment, the signal generator takes the form of a solid state pressure sensing transducer, such as a piezoresistive transducer sensor for sensing force transmitted through the lever mechanism. A central processing unit is provided in the preferred embodiment for receiving the electronic output signal from the signal generator and for generating a processed electronic output signal in accordance with a control program stored in memory. A display can be provided for receiving the output signal and for displaying a visual readout of information, such as relative speed of the fluid flow or marine vessel, based on the output signal.