Thomas O Rowe

US Patent:

7467390, Dec 16, 2008

Filed:

Apr 1, 2003

Appl. No.:

10/404334

Inventors:

David Blair Gilgen - Raleigh NC, US
Thomas Owings Rowe - Chapel Hill NC, US

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G06F 9/46

US Classification:

719318, 718102, 718104

Abstract:

The present invention is an enhanced staged event-driven architecture (SEDA) stage. The enhanced SEDA stage can include an event queue configured to enqueue a plurality of events, an event handler programmed to process events in the event queue, and a thread pool coupled to the event handler. A resource manager further can be coupled to the thread pool and the event queue. Moreover, the resource manager can be programmed to allocate additional threads to the thread pool where a number of events enqueued in the event queue exceeds a threshold value and where all threads in the thread pool are busy.

US Patent:

8082291, Dec 20, 2011

Filed:

Apr 27, 2009

Appl. No.:

12/430159

Inventors:

Daniel A. Gisolfi - Hopewell NY, US
David L. Kaminsky - Chapel Hill NC, US
Rodney A. Smith - Smyrna GA, US
Thomas O. Rowe - Chapel Hill NC, US

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G06F 15/16

US Classification:

709201, 709202, 709205

Abstract:

A system and method of providing data to a mashup application may involve receiving a request from a mashup application and supplying first data to the mashup application in response to the request. Mashup information can be received from the mashup application, wherein the mashup information indicates an inclusion of the first data with second data in the execution of the mashup application. The mashup information may be stored and analyzed to identify relationships between previously unrelated data.

US Patent:

8230447, Jul 24, 2012

Filed:

Oct 22, 2008

Appl. No.:

12/256092

Inventors:

David Blair Gilgen - Raleigh NC, US
Thomas Owings Rowe - Chapel Hill NC, US

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G06F 9/46

US Classification:

719318, 718104

Abstract:

The present invention is an enhanced staged event-driven architecture (SEDA) stage. The enhanced SEDA stage can include an event queue configured to enqueue a plurality of events, an event handler programmed to process events in the event queue, and a thread pool coupled to the event handler. A resource manager further can be coupled to the thread pool and the event queue. Moreover, the resource manager can be programmed to allocate additional threads to the thread pool where a number of events enqueued in the event queue exceeds a threshold value and where all threads in the thread pool are busy.

US Patent:

8352541, Jan 8, 2013

Filed:

Oct 26, 2011

Appl. No.:

13/281791

Inventors:

Daniel A. Gisolfi - Hopewell NY, US
David L. Kaminsky - Chapel Hill NC, US
Rodney A. Smith - Smyrna GA, US
Thomas O. Rowe - Chapel Hill NC, US

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G06F 15/16

US Classification:

709202, 709201, 709205, 709206

Abstract:

A system and method of providing data to a mashup application may involve receiving a request from a mashup application and supplying first data to the mashup application in response to the request. Mashup information can be received from the mashup application, wherein the mashup information indicates an inclusion of the first data with second data in the execution of the mashup application. The mashup information may be stored and analyzed to identify relationships between previously unrelated data.

US Patent:

8484282, Jul 9, 2013

Filed:

Mar 21, 2002

Appl. No.:

10/103400

Inventors:

Zackary A. James - Raleigh NC, US
Thomas O. Rowe - Chapel Hill NC, US

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G06F 15/16

US Classification:

709203, 709217, 709223

Abstract:

A high-speed content transformation method, system and apparatus. The method can include inspecting a request for transcoded content to determine input documents required to produce the requested transcoded content; determining whether the input documents have been characterized as standalone, and further determining freshness criteria for the input documents which are determined to have been characterized as standalone; locating in cache storage previously generated transcoded content corresponding to the input documents determined to have been characterized as standalone; and, serving the previously generated transcoded content in response to the request rather than generating the requested transcoded content using the input documents where the previously transcoded content meets the freshness criteria.

US Patent:

8623854, Jan 7, 2014

Filed:

Jun 13, 2011

Appl. No.:

13/159016

Inventors:

Daniel M. Sullivan - Tampa FL, US
Joel G. Turner - Tampa FL, US
Thomas C. Rowe - Gainesville FL, US
David A. Ostrov - Gainesville FL, US

Assignee:

H. Lee Moffitt Cancer Center and Research Institute, Inc. - Tampa FL
University of Florida Research Foundation, Inc. - Gainesville FL

International Classification:

A01N 43/00
A61K 31/33
A01N 57/00
A61K 31/66
A01N 43/66
A61K 31/53
A01N 43/50
A61K 31/415

US Classification:

514183, 514124, 514244, 514245, 514401

Abstract:

A method of treating cancer in a subject comprising the step of administering to the subject in need thereof an effective amount of a combination of a compound that binds a nuclear export signal (NES inhibitor) on topoisomerase IIα and a topoisomerase inhibitor. Twenty small molecule inhibitors (SMI) that bind to the two nuclear export sequences (NES) topo IIα have been identified from the NCI database using computer-generated molecular modeling. These SMI will improve the effectiveness of topo II directed therapeutics, particularly in the treatment of diseases such as multiple myeloma (MM). In vitro apoptosis assays indicate that these drugs may be effective as single agents or in combination with currently used cancer drugs that target topo II.

US Patent:

20020112096, Aug 15, 2002

Filed:

Jan 9, 2002

Appl. No.:

10/043574

Inventors:

David Kaminsky - Chapel Hill NC, US
David Johnson - Apex NC, US
David Ogle - Cary NC, US
Thomas Rowe - Chapel Hill NC, US
Gregory DeKoenigsberg - Durham NC, US
Daniel Gajewski - Chapel Hill NC, US

International Classification:

G06F009/46

US Classification:

709/330000

Abstract:

Information/web page content is provided to a client and tailored to specific users by including user or session-specific identity data in the initial query. The identity data are obtained from reading a code from a physical object, combining the code with information stored within the client, and embedding the result in the initial query. Before transmitting the query, the data can be compressed using a technique that resists inadvertent expansion caused by URL encoding. A server receiving the query operates on the identity data using, for example, a scoring algorithm and maps the query to a target URL specifying the location of the tailored information. If the file associated with the target URL cannot be located, the server accesses an error handling system to provide the user with alternative content. The server logs the query, including the associated target URL, providing a data warehouse capability.

US Patent:

59580135, Sep 28, 1999

Filed:

Sep 11, 1997

Appl. No.:

8/927777

Inventors:

Thomas Francis King - Louisville CO
Bradley Thomas Marchesseault - Cary NC
Thomas Owings Rowe - Chapel Hill NC
Yih-Shin Tan - Raleigh NC

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G06F 1700

US Classification:

709227

Abstract:

A session is conducted with an application resident on a host computer by loading terminal information at a computer, operatively associated with the host computer and which is part of a network including a plurality of resource locations, from a host access resource location of the plurality of resource locations. The terminal emulation information is processed to conduct a session between the computer and the application. A resource location of the plurality of resource locations is then accessed from the computer while the session persists. The terminal emulation information may be downloaded to the computer from a server of the network. According to one aspect, a common environment capable of being produced under a plurality of different computer operating systems, e. g. , a Java environment, is produced at the computer. The terminal emulation information is processed under the common environment to thereby conduct a session between the computer and the application.