Thomas C Shaffer

US Patent:

7909031, Mar 22, 2011

Filed:

Jun 9, 2005

Appl. No.:

11/149114

Inventors:

Thomas H. Shaffer - Chadds Ford PA, US
Marla R. Wolfson - Wyndmoor PA, US

Assignee:

Temple Univesity - Of The Commonwealth System of Higher Education - Philadelphia PA

International Classification:

A61M 16/00
A61M 16/10
A61M 15/00
A61M 11/00

US Classification:

12820325, 12820315, 12820312, 12820024, 12820014

Abstract:

The present invention includes a transient method of delivering a biological agent in a breathable liquid to a lung of a patient. The present invention includes a steady state method of delivering a biological agent in a breathable liquid to a lung of a patient. The steps of both the transient delivery method and the steady state delivery method can be controlled by a servo-control unit. A supplementary biological agent delivery step can be performed in both the transient method of delivering a biological agent and the steady state method of delivering a biological agent.

US Patent:

8034011, Oct 11, 2011

Filed:

Oct 18, 2006

Appl. No.:

12/083253

Inventors:

Thomas H. Shaffer - Chadds Ford PA, US
Marla R. Wolfson - Wyndmoor PA, US

Assignee:

Temple University—Of The Commonwealth System of Higher Education - Philadelphia PA

International Classification:

A61F 5/00
A61F 5/24
A61F 5/28
A61B 5/103
A61B 5/117
A47C 20/00

US Classification:

602 19, 5630, 600587

Abstract:

A thoracic stabilizer for limiting anterior chest wall collapse includes a platform supporting a patient and a pair of lateral supports contacting opposite sides of the patient's chest wall and applying force to limit collapse of the chest wall. The force applied by the lateral supports is varied depending on the force applied to the platform by the patient. The stabilizer includes a retractometer measuring the collapse of the chest wall. According to one embodiment, the stabilizer includes a controller that varies the force applied to the chest wall in closed-loop fashion based on the chest wall collapse measured by the retractometer using an algorithm of the controller. According to one embodiment, the stabilizer includes motors moving the lateral supports. According to another embodiment, the stabilizer includes a hydraulic system and the lateral supports include expandable fluid-filled members.

US Patent:

8375943, Feb 19, 2013

Filed:

Mar 17, 2011

Appl. No.:

13/050027

Inventors:

Thomas H. Shaffer - Chadds Ford PA, US
Marla R. Wolfson - Wyndmoor PA, US

Assignee:

Temple University—Of The Commonwealth System of Higher Education - Philadelphia PA

International Classification:

A61M 16/00
A61M 16/10
A61M 15/00
A61M 11/00

US Classification:

12820325, 12820315, 12820312, 12820024, 12820014

Abstract:

The present invention includes a transient method of delivering a biological agent in a breathable liquid to a lung of a patient. The present invention includes a steady state method of delivering a biological agent in a breathable liquid to a lung of a patient. The steps of both the transient delivery method and the steady state delivery method can be controlled by a servo-control unit. A supplementary biological agent delivery step can be performed in both the transient method of delivering a biological agent and the steady state method of delivering a biological agent.

US Patent:

8375952, Feb 19, 2013

Filed:

Aug 8, 2008

Appl. No.:

12/228019

Inventors:

Thomas L. Miller - Wilmington DE, US
Thomas H. Shaffer - Chadds Ford PA, US
Mary Theroux - Newark DE, US
John Bernardi - Swedesboro NJ, US

Assignee:

The Nemours Foundation - Jacksonville FL

International Classification:

A61M 16/00
A62B 7/00
A62B 9/06

US Classification:

12820714, 12820026, 12820418, 12820715

Abstract:

A system for unilateral lung ventilation includes an endotracheal tube and a blocking device for blocking the bronchus of a non-ventilated lung to prevent a ventilation medium from entering the lung. The blocking device includes an inflatable member supported by a catheter having an inflation lumen for inflating the inflatable member. The catheter includes at least one lung treatment lumen for delivering a therapeutic agent to the non-ventilated lung. An inner channel within the main channel and a side branch provide a guideway for the blocking device within the tube. A valve may be included to close the side branch when the blocking device is removed from the inner channel for parallel flow of ventilating gas in the main and inner channels. A method of using the system provides for ventilation/perfusion (V/Q) matching by respectively delivering cooled air and nitric oxide to the non-ventilated and ventilated lungs.

US Patent:

8408202, Apr 2, 2013

Filed:

Jan 25, 2008

Appl. No.:

12/449331

Inventors:

Thomas H. Shaffer - Chadds Ford PA, US
Marla R. Wolfson - Wyndmoor PA, US

Assignee:

Temple University—Of The Commonwealth System of Higher Education - Philadelphia PA

International Classification:

A61M 16/00
A61M 15/00

US Classification:

12820325, 12820315

Abstract:

An open-circuit liquid ventilation system includes a reservoir containing a breathable liquid, a patient interface receiving breathable liquid from the reservoir, a pump directing breathable liquid from the reservoir to the patient, a controller for the pump, and a tank for storing used breathable liquid. The system may be passive regarding expired liquid. Alternatively, the system may be active and include a bypass line connected to the pump such that used breathable liquid is drawn from the patient. The patient interface may be adapted to interface a gas ventilation system to facilitate a rapid conversion from gas to liquid ventilation. The system may include sensors monitoring pressure and volume parameters and may include an output displaying information including schematics and real time tracings regarding a ventilation procedure.

US Patent:

8535691, Sep 17, 2013

Filed:

Feb 16, 2006

Appl. No.:

11/276180

Inventors:

Thomas H. Shaffer - Chadds Ford PA, US
Robert G. Stern - Tucson AZ, US
Marla R. Wolfson - Wyndmoor PA, US

Assignee:

Peach Technologies, LLC. - Philadelphia PA

International Classification:

A61K 9/00

US Classification:

424400

Abstract:

A subject is confined in a closed environment at an elevated pressure through which perfluorochemical fluid containing dissolved oxygen is circulated to treat disease or injury.

US Patent:

8596306, Dec 3, 2013

Filed:

Nov 6, 2009

Appl. No.:

12/613625

Inventors:

Thomas H. Shaffer - Chadds Ford PA, US
Robert G. Stern - Tucson AZ, US
Marla R. Wolfson - Wyndmoor PA, US

Assignee:

Synthetic Gas Solutions, LLC - DE

International Classification:

B65B 1/04
B01F 13/10

US Classification:

141 9, 141 38, 152415

Abstract:

Vehicle tires are filled with perfluorocarbon gas to extend tire life.

US Patent:

20060191535, Aug 31, 2006

Filed:

Feb 25, 2005

Appl. No.:

11/065748

Inventors:

Thomas Shaffer - Chadds Ford PA, US
Joseph Tuckosh - Hockessin DE, US
Thomas Miller - Wilmington DE, US

Assignee:

The Nemours Foundation - Wilmington DE

International Classification:

A61M 16/00
A62B 7/00
F16K 31/02

US Classification:

128204180, 128204220

Abstract:

The present invention includes a method for treating an individual suffering from decompression sickness, a gas mixture that can be used to treat the individual, and an apparatus that can be used to administer the gas mixture. The method includes administering a gas mixture of oxygen and a therapeutically effective amount of nitric oxide gas to the individual. The gas mixture can include a mixture of oxygen, helium and, nitric oxide gases. The gas mixture can be administered using an apparatus that can be worn by the individual. The apparatus includes dispensers for gases, a gas blender to mix the gases, an inspiratory passage, a face mask substantially conformable with the individual's face, and an expiratory passage. When the individual wearing the face mask inhales, the gas mixture travels from the gas blender, through the inspiratory passage to the face mask. The gas mixture is then inhaled by the individual. When the individual exhales a breath, the breath travels from the face mask through the expiratory passage.