Thomas R Singleton

US Patent:

47330066, Mar 22, 1988

Filed:

Aug 18, 1983

Appl. No.:

6/524508

Inventors:

Thomas C. Singleton - Chesterfield MO
Frank E. Paulik - Creve Coeur MO

Assignee:

Monsanto Company - St. Louis MO

International Classification:

C07C 5110
C07C 5112
C07C 5308
C07C 6736
C07C 6737

US Classification:

562519

Abstract:

The present invention provides for an improved process wherein an olefin, an alcohol, or an ester, halide or ether derivative of said alcohol is reacted with carbon monoxide in a liquid phase in the presence of a catalyst system that contains (a) a rhodium component, and (b) and iodine or bromine component. By passing at least a portion of the liquid reaction mass from the reaction zone to a separation zone of substantially lower CO partial pressure, at least a portion of the carbonylation products, as well as unreacted carbon monoxide, inert gases and unreacted olefin, alcohol or alcohol derivatives are vaporized and can be withdrawn from the separation zone. Precipitation of the rhodium catalyst under carbon monoxide deficient conditions is prevented or retarded by addition to the carbon monoxide deficient zones of the system of a catalyst stabilizer which is a germanium (IV) compound, an alkali metal compound, and mixtures thereof.