Timothy W Pontz

age ~55

from Seattle, WA

Also known as:
  • Timothy Pontz
  • Timothy William Pontz
  • Tim Pontz
  • Tmothy Pontz

Timothy Pontz Phones & Addresses

  • Seattle, WA
  • Shaw Island, WA
  • 138 Huron Ave, Cambridge, MA 02138 • 6179452007
  • Watertown, MA
  • Arlington, MA
  • Brighton, MA
  • Pittsburgh, PA
  • Plainsboro, NJ
  • Lancaster, PA
  • Somerville, MA

Us Patents

  • Chemical Compounds

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  • US Patent:
    8461170, Jun 11, 2013
  • Filed:
    Aug 2, 2011
  • Appl. No.:
    13/196189
  • Inventors:
    Brian Aquila - Waltham MA, US
    Victor Kamhi - Waltham MA, US
    Bo Peng - Waltham MA, US
    Timothy Pontz - Waltham MA, US
    Jamal Carlos Saeh - Waltham MA, US
    Kumar Thakur - Waltham MA, US
    Bin Yang - Waltham MA, US
  • Assignee:
    Astrazeneca AB - Sodertalje
  • International Classification:
    A01N 43/54
    A61K 31/505
  • US Classification:
    514275, 544330, 544333, 544334
  • Abstract:
    The present invention relates to compounds of Formula (I) and/or Formula (Ia):.
  • Selected Fused Heterocyclics And Uses Thereof

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  • US Patent:
    20060041128, Feb 23, 2006
  • Filed:
    Aug 18, 2005
  • Appl. No.:
    11/206888
  • Inventors:
    Brian Aquila - Waltham MA, US
    Michael Block - Waltham MA, US
    Audrey Davies - Waltham MA, US
    Jayachandran Ezhuthachan - Waltham MA, US
    Timothy Pontz - Waltham MA, US
    Daniel Russell - Waltham MA, US
    Maria-Elena Theoclitou - Waltham MA, US
    XiaoLan Zheng - Waltham MA, US
  • Assignee:
    AstraZeneca AB - Sodertalje
  • International Classification:
    A61K 31/519
    C07D 498/02
    C07D 491/02
  • US Classification:
    544253000, 514260100
  • Abstract:
    This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
  • Enantiomers Of Selected Fused Heterocyclics And Uses Thereof

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  • US Patent:
    20060041129, Feb 23, 2006
  • Filed:
    Aug 18, 2005
  • Appl. No.:
    11/207128
  • Inventors:
    Brian Aquila - Waltham MA, US
    Michael Howard Block - Waltham MA, US
    Audrey Davies - Waltham MA, US
    Jayachandran Ezhuthachan - Waltham MA, US
    Timothy Pontz - Waltham MA, US
    Daniel John Russell - Waltham MA, US
    Maria-Elena Theoclitou - Waltham MA, US
    XiaoLan Zheng - Waltham MA, US
  • Assignee:
    AstraZeneca AB - Sodertalje
  • International Classification:
    A61K 31/519
    C07D 498/02
    C07D 491/02
  • US Classification:
    544253000, 514260100
  • Abstract:
    This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
  • Novel Fused Heterocycles And Uses Thereof

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  • US Patent:
    20060063751, Mar 23, 2006
  • Filed:
    Aug 18, 2005
  • Appl. No.:
    11/207089
  • Inventors:
    Brian Aquila - Waltham MA, US
    Michael Block - Waltham MA, US
    Audrey Davies - Waltham MA, US
    Jayachandran Ezhuthachan - Waltham MA, US
    Sandra Filla - Brownsberg IN, US
    Richard Luke - Macclesfield, GB
    Timothy Pontz - Waltham MA, US
    Daniel Russell - Waltham MA, US
    Maria-Elena Theoclitou - Waltham MA, US
    XiaoLan Zheng - Waltham MA, US
  • Assignee:
    AstraZeneca AB - Sodertalje
  • International Classification:
    A61K 31/513
    C07D 417/02
    C07D 413/02
    C07D 403/02
  • US Classification:
    514210200, 514269000, 544310000
  • Abstract:
    This invention relates to novel compounds having the formula (I) wherein R, R, R, R, R, R, R, Rand Rare as defined in the specification and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
  • Pyrazoles And Methods Of Making And Using The Same

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  • US Patent:
    20060264440, Nov 23, 2006
  • Filed:
    Feb 12, 2004
  • Appl. No.:
    10/545179
  • Inventors:
    Lihong Sun - Arlington MA, US
    Feng Shan - Braintree MA, US
    Claudio Chuaqui - Somerville MA, US
    Mark Cornebise - Watertown MA, US
    Timothy Pontz - Brighton MA, US
    Mary Carter - Arlington MA, US
    Juswinder Singh - Ashland MA, US
    Leona Ling - Winchester MA, US
    Russell Petter - Stow MA, US
  • Assignee:
    BIOGEN IDEC MA INC. - Cambridge MA
  • International Classification:
    A61K 31/522
    A61K 31/52
    A61K 31/519
    A61K 31/517
    C07D 473/02
    C07D 487/04
  • US Classification:
    514249000, 544238000, 544235000, 544281000, 544284000, 544353000, 544277000, 544278000, 514252020, 514252040, 514263200, 514260100, 514259100, 514266200, 514266210
  • Abstract:
    The invention is based on the discovery that compounds of formula I possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound of formula I (I).
  • Selected Fused Heterocyclics And Uses Thereof

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  • US Patent:
    20070249636, Oct 25, 2007
  • Filed:
    Aug 16, 2005
  • Appl. No.:
    11/573671
  • Inventors:
    Brian Aquila - Marlborough MA, US
    Michael Block - Sudbury MA, US
    Audrey Davies - Waltham MA, US
    Jayachandran Ezhuthachan - Brookline MA, US
    Timothy Pontz - Cambridge MA, US
    Daniel Russell - Natick MA, US
    Marie-Elena Theoclitou - Cheshire, GB
    XiaoLan Zheng - Waltham MA, US
  • Assignee:
    ASTRAZENECA AB - Sodertalje
  • International Classification:
    A61K 31/519
    A61P 35/00
    C07D 239/00
    C07D 261/00
    C07D 275/00
    C07D 487/14
    C07D 498/04
    C07D 513/04
  • US Classification:
    514260100, 544255000
  • Abstract:
    This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
  • Azine-Carboxamides As Anti-Cancer Agents

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  • US Patent:
    20070259849, Nov 8, 2007
  • Filed:
    Jun 29, 2005
  • Appl. No.:
    11/570065
  • Inventors:
    Brian Aquila - Marlborough MA, US
    Stephanos Ioannidis - Cambridge MA, US
    Paul Lyne - Arlington MA, US
    Timothy Pontz - Cambridge MA, US
  • Assignee:
    ASTRAZENECA AB - Sodertalje
  • International Classification:
    C07D 239/42
    A61K 31/435
    A61K 31/495
    A61P 35/00
    C07D 241/24
    C07D 403/04
    C07D 405/12
    C07D 403/06
    C07D 401/04
    C07D 213/81
    C07D 213/82
    C07D 239/28
  • US Classification:
    514211050, 514235500, 514235800, 514252140, 514255050, 514256000, 514318000, 514326000, 514354000, 514357000, 540507000, 544121000, 544124000, 544242000, 544357000, 544405000, 546193000, 546276400, 546336000, 546340000
  • Abstract:
    The invention relates to chemical compounds, of the formula (I): or pharmaceutically acceptable salts thereof, which possess B-Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
  • Chemical Compounds

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  • US Patent:
    20080146570, Jun 19, 2008
  • Filed:
    Jan 24, 2006
  • Appl. No.:
    11/814246
  • Inventors:
    Brian Aquila - Marlborough MA, US
    Paul Lyne - Arlington MA, US
    Timothy Pontz - Cambridge MA, US
  • Assignee:
    ASTRAZENECA AB - Sodertalje
  • International Classification:
    A61K 31/5377
    C07D 295/00
    A61K 31/506
    A61P 35/00
    C07D 239/00
  • US Classification:
    5142358, 544328, 514256, 544122
  • Abstract:
    The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof, of the formula (I): which possess B-Raf inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.

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Timothy Ptz Bright MA

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