- Princeton NJ, US Daniel Cohen - New York NY, US Ranjan Mukherjee - Churchville PA, US Timothy P. Reilly - New Hope PA, US Rose C. Christian - Hopewell NJ, US Dasa Lipovsek - Pepperell MA, US Ray Camphausen - Wayland MA, US John Krupinski - Flemington NJ, US
Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide, optionally modified with at least one non-naturally-encoded amino acid, and/or optionally fused to a fusion partner.
- Princeton NJ, US Daniel Cohen - New York NY, US Ranjan Mukherjee - Churchville PA, US Timothy P. Reilly - New Hope PA, US Rose C. Christian - Hopewell NJ, US Dasa Lipovsek - Pepperell MA, US Ray Camphausen - Wayland MA, US John Krupinski - Flemington NJ, US
Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide, optionally modified with at least one non-naturally-encoded amino acid, and/or optionally fused to a fusion partner.
- Princeton NJ, US Daniel Cohen - New York NY, US Ranjan Mukherjee - Churchville PA, US Timothy P. Reilly - New Hope PA, US Rose C. Christian - Hopewell NJ, US Dasa Lipovsek - Cambridge MA, US Ray Camphausen - Wayland MA, US John Krupinski - Flemington NJ, US
International Classification:
A61K 38/18
Abstract:
Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide, optionally modified with at least one non-naturally-encoded amino acid, and/or optionally fused to a fusion partner.
- Princeton NJ, US Daniel COHEN - New York NY, US Ranjan MUKHERJEE - Churchville PA, US Timothy P. REILLY - New Hope PA, US Rose C. CHRISTIAN - Lawrenceville NJ, US Dasa LIPOVSEK - Cambridge MA, US Ray CAMPHAUSEN - Wayland MA, US John KRUPINSKI - Flemington NJ, US
International Classification:
A61K 38/18
Abstract:
Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide, optionally modified with at least one non-naturally-encoded amino acid, and/or optionally fused to a fusion partner.
Modified Fgf-21 Polypeptides Comprising An Internal Deletion And Uses Thereof
- Princeton NJ, US Daniel COHEN - New York NY, US Ranjan MUKHERJEE - Churchville PA, US Timothy P. REILLY - New Hope PA, US Rose C. CHRISTIAN - Lawrenceville NJ, US Dasa LIPOVSEK - Cambridge MA, US Ray CAMPHAUSEN - Wayland MA, US John KRUPINSKI - Flemington NJ, US
International Classification:
C07K 14/50 A61K 47/48
Abstract:
Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide, optionally modified with at least one non-naturally-encoded amino acid, and/or optionally fused to a fusion partner.
- Princeton NJ, US Daniel COHEN - New York NY, US Ranjan MUKHERJEE - Churchville PA, US Timothy P. REILLY - New Hope PA, US Rose C. CHRISTIAN - Lawrenceville NJ, US Dasa LIPOVSEK - Cambridge MA, US Ray CAMPHAUSEN - Wayland MA, US John KRUPINSKI - Flemington NJ, US
International Classification:
C07K 14/50 A61K 38/18
Abstract:
Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide, optionally modified with at least one non-naturally-encoded amino acid, and/or optionally fused to a fusion partner.
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