Timothy M Swager from 18 Copley St, Newton, MA 02458, age 64, Phone: 6179698074

Us Patents

Electroluminescence In Light Emitting Polymers Featuring Deaggregated Polymers
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US Patent:

6623870, Sep 23, 2003
Filed:

Jul 29, 1997
Appl. No.:

08/901888
Inventors:

Arthur J. Epstein - Bexley OH
Yunzhang Wang - Columbus OH
Darren D. Gebler - Columbus OH
Timothy M. Swager - Newton MA
Assignee:

The Ohio State University - Columbus OH
International Classification:

H05B 3314
US Classification:

428690, 428917, 313504, 313506, 526265, 526268, 526281, 528205, 528211, 528219
Abstract:

In general terms, the present invention includes a light emitting polymeric material the light emitting polymeric material capable of producing electroluminescence upon being provided with a flow of electrons, the light emitting polymeric material comprising a plurality of polymeric chains comprising polymeric chains each having substituent moieties of sufficient number and size and extending from the polymeric chain and about a substantial portion of the circumference about the polymer chain so as to maintain the polymeric chains in a sufficiently deaggregated state (referred to herein as a âstrappedâ polymer), so as to substantially prevent the redshifting of the electroluminescence and the lowering of light emission efficiency of the electroluminescence.

Polymers With High Internal Free Volume
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US Patent:

6783814, Aug 31, 2004
Filed:

Aug 21, 2001
Appl. No.:

09/935060
Inventors:

Timothy M. Swager - Newton MA
Timothy M. Long - Cambridge MA
Zhengguo Zhu - Cambridge MA
Assignee:

Massachusetts Institute of Technology - Cambridge MA
International Classification:

A47G 3304
US Classification:

428 11, 428 1, 525 63, 2522994, 349 1
Abstract:

Shape-persistent organic materials, including polymers, with large degrees of interior free volume are described, along with behaviors and phenomena enabled by their unique properties. One class of such a material is built up from triptycene base moieties wherein three benzene rings are bridged together about a [2. 2. 2] tricyclic ring system. These units can be assembled into discreet molecules and polymers. These materials and/or formulations thereof with liquid crystals or polymers are useful for the complexation of chemicals and/or polymers; they have very low dielectric constants for use as coatings in dielectric circuits, they provide additional ordering mechanisms in liquid crystals, and they display unusual mechanical responses when subjected to electrochemical, chemical, or mechanical stimuli.

Electroluminescence In Light Emitting Polymers Featuring Deaggregated Polymers
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US Patent:

6962757, Nov 8, 2005
Filed:

Aug 27, 2003
Appl. No.:

10/649056
Inventors:

Arthur J. Epstein - Bexley OH, US
Yunzhang Wang - Duncan SC, US
Darren D. Gebler - Sleepy Hollow NY, US
Timothy M. Swager - Newton MA, US
Assignee:

The Ohio State Universtiy Research Foundation - Columbus OH
International Classification:

H05B033/14
C09K011/06
US Classification:

428690, 428917, 313504, 313506, 257 40, 25230135
Abstract:

In general terms, the present invention includes a light emitting polymeric material the light emitting polymeric material capable of producing electroluminescence upon being provided with a flow of electrons, the light emitting polymeric material comprising a plurality of polymeric chains comprising polymeric chains each having substituent moieties of sufficient number and size and extending from the polymeric chain and about a substantial portion of the circumference about the polymer chain so as to maintain the polymeric chains in a sufficiently deaggregated state (referred to herein as a “strapped” polymer), so as to substantially prevent the redshifting of the electroluminescence and the lowering of light emission efficiency of the electroluminescence.

Stereoisomers Of P-Hydroxy-Milnacipran, And Methods Of Use Thereof
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US Patent:

7038085, May 2, 2006
Filed:

Oct 22, 2003
Appl. No.:

10/691465
Inventors:

Roman V. Rariy - Allston MA, US
Michael Heffernan - Hingham MA, US
Stephen L. Buchwald - Newton MA, US
Timothy M. Swager - Newton MA, US
Assignee:

Collegium Pharmaceutical, Inc. - Cumberland RI
International Classification:

C07C 233/05
A61K 31/165
US Classification:

564165, 564164, 564171, 564190, 514620, 514624
Abstract:

The present invention relates generally to the enantiomers of para-hydroxy-milnacipran or congeners thereof. Biological assays revealed that racemic para-hydroxy-milnacipran is approximately equipotent in inhibiting serotonin and norepinephrine uptake (IC=28. 6 nM for norepinephrine, IC=21. 7 nM for serotonin). Interestingly, (+)-para-hydroxy-milnacipran is a more potent inhibitor of norepinephrine uptake than serotonin uptake (IC=10. 3 nM for norepinephrine, IC=22 nM for serotonin). In contrast, (−)-para-hydroxy-milnacipran is a more potent inhibitor of serotonin uptake compared to norepinephrin uptake (IC=88. 5 nM for norepinephrine, IC=40. 3 nM for serotonin). The invention also relates to salts and prodrug forms of the aforementioned compounds. In certain embodiments, the compounds of the present invention and a pharmaceutically acceptable excipient are combined to prepare a formulation for administration to a patient. Finally, the present invention relates to methods of treating mammals suffering from various afflictions, e. g.

Emissive, High Charge Transport Polymers
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US Patent:

7041910, May 9, 2006
Filed:

Jul 15, 2003
Appl. No.:

10/621041
Inventors:

Timothy M. Swager - Newton MA, US
Steffen Zahn - Pennsburg PA, US
Assignee:

Massachusetts Institute of Technology - Cambridge MA
International Classification:

H01B 7/00
US Classification:

174110, 2522994, 252582, 257E21259, 349 1, 428 11, 525 63
Abstract:

The present invention generally relates to stable emissive aggregates of polymers. The aggregates are composed of various polymer molecules arranged in such a way as to allow extended electronic couplings between nearby polymer molecules, enhancing exciton transport, while minimizing the effects of quenching due to interchain interactions. For example, the polymer molecules may be arranged in a non-aligned, electronically-communicative manner (for example, at an oblique angle), stabilized by various methods such as chemical linkages or physical interactions. Within the aggregate, electronic interactions along the polymer molecule may extend to nearby polymer molecules, which may be observed as a shift in the absorption spectra relative to a random dispersion. Light emitted from the aggregate may be polarized in some cases, for example, linearly or circularly, which may be caused by chiral arrangements of polymers within the aggregate (the polymers themselves may or may not be chiral). These aggregates may find widespread use, for example, in enantiomeric detectors, electrochemical devices, photodetectors, organic diodes, sensors, light sources, or photovoltaic devices.

Molecular Actuators, And Methods Of Use Thereof
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US Patent:

7138075, Nov 21, 2006
Filed:

Mar 19, 2003
Appl. No.:

10/392354
Inventors:

Patrick A. Anquetil - Boston MA, US
Ian W. Hunter - Lincoln MA, US
John D. Madden - Vancouver, CA
Peter G. Madden - Somerville MA, US
Anthony E. Pullen - Belmont MA, US
Timothy M. Swager - Newton MA, US
Bing Xu - Kowloon, HK
Hsiao-hua Yu - Cambridge MA, US
Assignee:

Massachusetts Institute of Technology - Cambridge MA
International Classification:

H01B 1/00
C07D 495/00
US Classification:

252500, 549 17, 548527
Abstract:

The synthesis of thiophene based conducting polymer molecular actuators, exhibiting electrically triggered molecular conformational transitions is reported. Actuation is believed to be the result of conformational rearrangement of the polymer backbone at the molecular level, not simply ion intercalation in the bulk polymer chain upon electrochemical activation. Molecular actuation results from π—π stacking of thiophene oligomers upon oxidation, producing a reversible molecular displacement that leads to surprising material properties, such as electrically controllable porosity and large strains. The existence of active molecular conformational changes is supported by in situ electrochemical data. Single molecule techniques have been used to characterize the molecular actuators.

Insulated Nanoscopic Pathways, Compositions And Devices Of The Same
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US Patent:

7186355, Mar 6, 2007
Filed:

Feb 5, 2001
Appl. No.:

09/777725
Inventors:

Timothy M. Swager - Newton MA, US
Assignee:

Massachusetts Institute of Technology - Cambridge MA
International Classification:

H01B 1/00
H01B 1/12
H01B 1/04
H01B 1/06
H01L 29/08
H01L 35/24
H01L 51/00
G01N 27/26
C08F 290/14
H01L 29/43
US Classification:

252500, 252502, 252510, 252506, 204415, 422 98, 525 50, 257 40, 257139
Abstract:

The present invention relates to compositions which provide an insulated nanoscopic pathway. The pathway comprises molecules, polymers or nanoscopic particles capable of conducting charge integrated with nanoscopic switches which are capable of electronic communication with the charge-conducting species. Turning “on” the nanoscopic switch electronically “connects” the various molecules/particles, such that a continuous nanoscopic pathway results. The nanoscopic pathway can be used in a sensor, where the switches can act as receptors for analytes. Binding of an analyte can result in a variety of effects on the nanoscopic pathway, including altering the conductivity of the nanoscopic pathway.

Emissive Polymers And Devices Incorporating These Polymers
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US Patent:

7208122, Apr 24, 2007
Filed:

Dec 18, 2002
Appl. No.:

10/324064
Inventors:

Timothy M. Swager - Newton MA, US
Jye-Shane Yang - Ping-Chen, TW
Vance Williams - Somerville MA, US
Yi-Jun Miao - Chester VA, US
Claus G. Lugmair - San Jose CA, US
Igor A. Levitsky - Fall River MA, US
Jinsang Kim - Cambridge MA, US
Robert Deans - Cambridge MA, US
Assignee:

Massachusetts Institute of Technology - Cambridge MA
International Classification:

B32B 5/02
G01N 21/76
C08G 67/02
US Classification:

422 8205, 422 8208, 436172, 528392
Abstract:

The present invention relates to a class of luminescent and conductive polymer compositions having chromophores, and particularly solid films of these compositions exhibiting increased luminescent lifetimes, quantum yields and amplified emissions. These desirable properties can be provided through polymers having rigid groups designed to prevent polymer reorganization, aggregation or π-stacking upon solidification. These polymers can also display an unusually high stability with respect to solvent and heat exposures. The invention also relates to a sensor and a method for sensing an analyte through the luminescent and conductive properties of these polymers. Analytes can be sensed by activation of a chromophore at a polymer surface. Analytes include aromatics, phosphate ester groups and in particular explosives and chemical warfare agents in a gaseous state. The present invention also relates to devices and methods for amplifying emissions by incorporating a polymer having an energy migration pathway and/or providing the polymer as a block co-polymer or as a multi-layer.