E. Adam Kallel - Escondido CA, US Thomas Lau - San Diego CA, US Matthew H. McNeill - San Clemente CA, US Todd A. Miller - San Marcos CA, US Bao N. Nguyen - San Diego CA, US Richard J. Penuliar - San Diego CA, US Dean P. Phillips - San Marcos CA, US Daniel A. Ruppar - San Antonio TX, US Lin Zhi - San Diego CA, US Jackline E. Dalgard - Del Mar CA, US
Assignee:
Ligand Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 31/404 C07D 209/40
US Classification:
514418, 548483
Abstract:
Disclosed herein are compounds of Formula (I), (II), and (III).
Thrombopoietin Activity Modulating Compounds And Methods
E. Adam Kallel - Escondido CA, US Thomas Lau - San Diego CA, US Matthew H. McNeill - San Clemente CA, US Todd A. Miller - San Marcos CA, US Bao N. Nguyen - San Diego CA, US Dean P. Phillips - San Marcos CA, US Daniel A. Ruppar - San Antonio TX, US Lin Zhi - San Diego CA, US Jackline E. Dalgard - Del Mar CA, US
Assignee:
Ligand Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 31/404 C07D 209/40
US Classification:
514418, 548483
Abstract:
Disclosed herein are compounds of Formula (I), (II), and (III).
Process For Making ()-3-(2,3-Dihydroxypropyl)-6-Fluoro-5-(2-Flouro-4- Iodophenylamino)-8-Methylpyrido[2,3-D]Pyrimidine-4,7()-Dione And Intermediates Thereof
David Paul Provencal - San Diego CA, US Yuxin Zhao - San Diego CA, US Todd Miller - San Diego CA, US Jonathon S. Salsbury - San Diego CA, US
Assignee:
Takeda Pharmaceutical Company Limited - Osaka
International Classification:
C07C 69/74
US Classification:
560 1
Abstract:
The present invention relates generally to processes of making (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione, intermediates thereof, and a process for making a particular polymorph of (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione.
Thrombopoietin Activity Modulating Compounds And Methods
E. Kallel - Escondido CA, US Thomas Lau - San Diego CA, US Matthew McNeill - San Clemente CA, US Todd Miller - San Marcos CA, US Bao Nguyen - San Diego CA, US Richard Penuliar - San Diego CA, US Dean Phillips - San Marcos CA, US Daniel Ruppar - San Antonio TX, US Lin Zhi - San Diego CA, US Jackline Dalgard - Del Mar CA, US
Disclosed herein are compounds, pharmaceutical compositions comprising the same, methods of modulating the activity a thrombopoietin receptor using the same, methods of identifying compounds as thrombopoietin receptor modulators, and methods of treating disease by administering a compound of the invention to a patient in need thereof.
Jon C. Loren - San Diego CA, US Todd Miller - San Marcos CA, US Bijan Pedram - San Diego CA, US Charlene V. Rowley - Chula Vista CA, US Yixing Shen - Encinitas CA, US Cornelis Arjan Van Oeveren - San Diego CA, US Lin Zhi - San Diego CA, US
Provided herein are compounds that bind to androgen receptors and modulate the activity and/or the amount of androgen receptors and to methods for making and using such compounds. Also provided are compositions including such compounds and methods for making and using such compositions.
Process For Making (R)-3-(2,3-Dihydroxypropyl)-6-Fluoro-5-(2-Flouro-4-Iodophenylamino)-8-Methylpyrido[2,3-D]Pyrimidine-4,7(3H,8H)-Dione And Intermediates Thereof
David Paul Provencal - San Diego CA, US Todd Miller - San Marcos CA, US Yuxin Zhao - San Diego CA, US Jonathon S. Salsbury - Madison WI, US
Assignee:
TAKEDA PHARMACEUTICAL COMPANY LIMITED - Osaka
International Classification:
C07D 471/04 C07D 213/84 C07C 229/00
US Classification:
544279, 546288, 560169
Abstract:
The present invention relates generally to processes of making (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione, intermediates thereof, and a process for making a particular polymorph of (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione.
Process For Making (R) -3-(2,3-Dihydroxypropyl)-6-Fluoro-5-(2-Flouro-4-Iodophenylamino)-8-Methylpyrido[2,3-D]Pyrimidine-4,7(3H,8H)-Dione And Intermediates Thereof
David Paul Provencal - , US Yuxin Zhao - San Diego CA, US Todd Miller - San Diego CA, US Jonathon S. Salsbury - San Diego CA, US
Assignee:
TAKEDA PHARMACEUTICAL COMPANY LIMITED - Osaka
International Classification:
C07D 471/04
US Classification:
544279
Abstract:
The present invention relates generally intermediates for making (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione.
Robert I. Higuchi - Solana Beach CA, US E. Adam Kallel - Escondido CA, US Cornelis Arjan Van Oeveren - San Diego CA, US Daniel A. Ruppar - San Diego CA, US Bijan Pedram - San Diego CA, US Thomas Lot Stevens Lau - San Diego CA, US Todd A. Miller - San Marcos CA, US
Provided herein are compounds having a structure selected from among Formula (I), Formula (II), Formula (III), Formula (IV), Formula (V) and Formula (VI) that are androgen receptor modulators and/or androgen receptor binding agents. Also disclosed are methods of making and using such compounds, including, but not limited to, using such compounds for treating various conditions.
Twin County Recovery Services Hudson, NY 2009 to 2013 Case ManagerHoystradt Construction Ancramdale, NY 2002 to 2003 CarpenterMcDonnell Douglas / Boeing Mesa, AZ 1997 to 2002 Electrical TechnicianGordon Danby, Inc Mesa, AZ 1995 to 1997 Arizona Vehicle Emissions Inspector
Education:
Columbia Greene Community College Greenport, NY 2009 Associates in Teaching CertificationAviation School of America San Diego, CA 2002 Certificate in Optics
2010 to Present Senior Commercial Credit AnalystFranklin Machine Products, Inc
2008 to 2010 Commercial Credit AnalystSallie Mae Financial Corporation
2001 to 2008 Senior Credit/Collection Supervisor
Education:
Arcadia University Glenside, PA 2012 Master of Business Administration in accordanceRowan University Glassboro, NJ 2010 Bachelor of Arts in Business Administration
Softmart Inc Downingtown, PA Oct 2006 to Jan 2013 Project ManagerSoftmart Inc
Jan 2008 to Sep 2012 Symantec Product SpecialistSoftmart Inc
Oct 2007 to Jan 2008 Account ManagerSoftmart Inc
Oct 2006 to Oct 2007 Customer Support SpecialistMusic123.com Cherry Hill, NJ Aug 2002 to Jun 2006 Product Manager/ BuyerMusic123.com Cherry Hill, NJ Aug 2002 to Dec 2002 Sales AssociateCue Records Philadelphia, PA 2001 to 2002 Genre Buyer/ Sales RepresentativeCDNOW Inc Fort Washington, PA 1998 to 2001 Affiliate Program Assistant Manager
Education:
Syracuse University Syracuse, NY 1992 to 1996 Bachelor of Science in Advertising
Rip Curl USA, Inc Costa Mesa, CA Dec 2007 to Jul 2011 Director of OperationsTYR Sport, Inc Huntington Beach, CA Sep 1999 to Dec 2007 Operations ManagerTYR Sport, Inc Huntington Beach, CA Jan 1998 to Sep 1999 Customer Service Manager / Allocation ManagerTYR Sport, Inc Huntington Beach, CA May 1997 to Jan 1998 Allocation ManagerTYR Sport, Inc Huntington Beach, CA Jun 1996 to May 1997 Customer Service Representative / Account ManagerRoad Runner Sports San Diego, CA Jun 1994 to Jun 1996 Sales Representative
Education:
California State University 1996 Bachelor of Science in Business Management
Jul 2013 to 2000 Lead BizTalk Developer (Fulltime)Illumina San Diego, CA Sep 2011 to Aug 2013 BizTalk DeveloperEBay/StubHub East Granby, CT May 2005 to Jul 2013 ASP.NET Programmer (Contractor)Bank of America Agoura Hills, CA Mar 2011 to Aug 2011 BizTalk Developer (Contractor)Orlando Health Orlando, FL Aug 2010 to Nov 2010 BizTalk Developer (Contractor)Specialized Technology Resources Enfield, CT May 2008 to Mar 2010 Lead BizTalk Developer (Fulltime)Evolution Benefits Avon, CT Apr 2007 to May 2008 BizTalk Developer
Dec 2011 to 2000 Substitute teacherSylvan Learning Center
Jun 2011 to 2000 Reading and Mathematics Teacher/TutorPhiladelphia School District Philadelphia, PA Sep 2010 to Nov 2011 7th Grade Mathematics and Science TeacherPhiladelphia School District Philadelphia, PA Jun 2010 to Jul 2010 Summer Program TeacherPhiladelphia School District Philadelphia, PA Oct 2009 to Jun 2010 Substitute teacher
Education:
Temple University Jan 2001 Bachelor of Science in Elementary Education
Civil Litigation Professional Malpractice Government Liability Medical Liability Dental Liability Automobile Negligence Insurance Defense Premises Liability Criminal Law
ISLN:
914892661
Admitted:
1998
University:
University of Florida, B.A.
Law School:
Stetson University, J.D.
News
Wash your hands if you touch the ocean in NC – and forget swimming, experts warn
We need to be loud and clear that swimming in coastal waters is currently a threat to public health, safety and welfare, said a statement issued by Todd Miller, executive director of the nonprofit federation.
Date: Sep 27, 2018
Category: Headlines
Source: Google
Hell and high water: Florence turned familiar haunts into an alien expanse
A few years ago, I was out on a boat on Bogue Sound with a person who knows as much about the coast as anyone. Todd Miller is the founder and executive director of the North Carolina Coastal Federation, which works to maintain the health of the states 12,000 miles of estuarian shoreline. Millers tned a little boy on Sunday night made their way through South Carolina on Wednesday, as the Pee Dee crested and shut down Interstate 95, perhaps the most important highway in the US. The same water that killed farm animals inland changed the complexion of Bogue Sound in front of Todd Millers house. The s
Date: Sep 21, 2018
Category: Headlines
Source: Google
Silverado, PGA Tour get a little payback from stars
onday's sectional at Lake Merced and Olympic include longtime tour pros Kevin Sutherland, Alex Cejka and Jeff Brehaut; Pebble Beach caddie Casey Boyns, a former California Amateur champion; local college standouts Brandon Hagy, Joel Stalter, Maverick McNealy, Cory McElyea and Cody Blick; and Todd Miller
Date: May 28, 2014
Category: Sports
Source: Google
Victim of ex-Gophers QB Nelson 'fighting for his life'
We know that there was at least one more person involved in this assault, Todd Miller, director of public safety for the city of Mankato, said at a news conference Monday. We have video of that individual, as well as video of a number of other persons that we are attempting to locate.
Date: May 12, 2014
Category: Sports
Source: Google
Ex-Gopher Philip Nelson released on $20K bail; 2nd attacker sought
The entire thing lasted five to 10 seconds, said Todd Miller, Mankatos public safety director. Mr. Nelson and Mr. Kolstad know each other and played football against each other in Mankato in high school.
Date: May 12, 2014
Category: Sports
Source: Google
Sundance: Lionsgate, CNN Films Team for Doc 'Dinosaur 13'
Director and producer Todd Miller has been a filmmaker for more than a decade, but he made his debut at Sundance with Dinosaur 13, which premiered at Eccles Theatre on Jan. 16. in the U.S. Documentary Category.
Date: Jan 17, 2014
Source: Google
Sundance Film Festival unwraps a fierce 2014 competition slate
"Dinosaur 13" (Director: Todd Miller) This documentary details the 1990 discovery of "Sue," one of the largest Tyrannosaurus rex specimens ever found, and the tangled legal battle over the fossils ownership that followed. This is one of the four "Day One" movies premiering on Jan. 16.
Mississippi Highway Patrol Cpl. Todd Miller said the motorhome blew a front tire, ran off Interstate 59 in Forrest County, Miss., and hit a tree in the median. He said two people were ejected from the motorhome. Benedict said he's not sure if Parker was one of them.
Date: Jan 08, 2012
Category: U.S.
Source: Google
Googleplus
Todd Miller
Lived:
Bensalem, PA Philadelphia, PA Yardley, PA Maineville, OH Levittown, PA
Work:
NBCUniversal - Information Security Operations Manager (2011) General Electric - Manager, Security Operations (2003-2011) Advanced Systems Consulting - Consultant (1999-2002) InfoTechnologies - Consultant (1998-1999) Elf Atochem North America - Help Desk Analyst (1997-1998)
Education:
Drexel University - Electrical/Computer Engineering
About:
Me!
Bragging Rights:
Married with three lovely, well-behaved (LOL) children.
Todd Miller
Lived:
Fairfield, OH San Diego, CA Norfolk, VA Oak Harbor, WA
Work:
United States Postal Service - Letter Carrier (2007) US Navy - Sonar Technician (1994-2005)
Education:
Diamond Oaks - Digital Electronics
Todd Miller
Lived:
Manistee, MI 49660 Onekama, MI 49675 East Lansing, MI 48823 Grand Rapids, MI La Jolla, CA