Todd Richard Swanson

US Patent:

55388523, Jul 23, 1996

Filed:

Jun 13, 1994

Appl. No.:

8/259046

Inventors:

Robert E. Carlson - Minnetonka MN
Todd A. Swanson - Chaska MN

Assignee:

Ecochem Research, Inc. - Chaska MN

International Classification:

G01N 3353
G01N 33535
G01N 33543

US Classification:

435 79

Abstract:

A method for determining qualitatively or quantitatively the presence of polychlorinated biphenyl in a test sample. The method includes the steps of: providing a known quantity of antibodies to polychlorinated biphenyl; providing a competitor that will bind to said antibodies in competition with polychlorinated biphenyl and having a lower affinity to said antibodies than said antibodies have to polychlorinated biphenyl; incubating said antibodies and said competitor in the presence of a test sample; and detecting the presence of polychlorinated biphenyl in the test sample. The competitor used in this method has one of the following structures: ##STR1## wherein A is selected from the group consisting of --NH--, --S--, --O--, --CH. sub. 2 --, --NH--C(O)--, --C(O)--NH--, --NH--C(O)--NH--, --NH--C(S)--NH--, --N(CH. sub. 3)--, --N(CH. sub. 3). sub.

US Patent:

62040057, Mar 20, 2001

Filed:

Mar 16, 1995

Appl. No.:

8/404887

Inventors:

Robert E. Carlson - Minnetonka MN
Todd A. Swanson - Chaska MN

Assignee:

Ecochem Research, Inc. - Chaska MN

International Classification:

G01N 3353
G01N 33543

US Classification:

435 79

Abstract:

The present invention provides a method for determining qualitatively or quantitatively the presence of toxic congeners of polychlorinated biphenyl in a test sample. The method includes the steps of: providing a known quantity of antibodies to the toxic polychlorinated biphenyl congener; providing a competitor that will bind to said antibodies in competition with the toxic polychlorinated biphenyl congener and having a lower affinity to said antibodies than said antibodies have to the toxic polychlorinated biphenyl congener; incubating said antibodies and said competitor in the presence of a test sample; and detecting the presence of the toxic polychlorinated biphenyl toxic congener in the test sample.