Described are low viscosity, hypotonic formulations containing one or more proteins, e.g., antibodies, at high concentration, uses of the formulations, and articles of manufacture. In particular, the formulations are useful and beneficial for the subcutaneous administration or delivery of a high concentration of a protein drug, such as an antibody, to a subject who is afflicted with a disease or condition that is treatable by the protein drug.
Cyrus Karkaria - Branford CT, US Tracy Chen - Clinton CT, US Rajeev Chillakuru - Chester CT, US Gan Wei - Hamden CT, US Saravanamoorthy Rajendran - Branford CT, US
International Classification:
A61K 38/18 A61K 31/724
US Classification:
514012000, 514058000
Abstract:
The present invention provides improved formulations comprising FGF-20, its fragments, derivatives, variants, homologs, analogs, or a combination thereof, and improved methods for production.
Concentrated Protein Formulations And Uses Thereof
Described are low viscosity, hypotonic formulations containing one or more proteins, e.g., antibodies, at high concentration, uses of the formulations, and articles of manufacture. In particular, the formulations are useful and beneficial for the subcutaneous administration or delivery of a high concentration of a protein drug, such as an antibody, to a subject who is afflicted with a disease or condition that is treatable by the protein drug.
The 50-basis-point cut should be out of question now, said Tracy Chen, portfolio manager at Brandywine Global Investment Management. The Feds easing and Chinas stimulus increases the likelihood of a no landing.
Date: Oct 06, 2024
Category: Business
Source: Google
Bond Traders Bet Big on the Fed Launching Into Rescue Mode
The market concern is that the Fed is lagging and that we are morphing from a soft landing to a hard landing, said Tracy Chen, a portfolio manager at Brandywine Global Investment Management. Treasuries are a good buy here because I do think the economy will continue to slow.