Tracy Lynn Deegan

US Patent:

20080207616, Aug 28, 2008

Filed:

Oct 13, 2005

Appl. No.:

11/577132

Inventors:

Brian Aquila - Marlborough MA, US
Les Dakin - Natick MA, US
Tracy Deegan - Salem MA, US
Stephanos Ioannidis - Cambridge MA, US
Stephen Lee - Waltham MA, US
Paul Lyne - Arlington MA, US
Timothy Pontz - Cambridge MA, US
Mei Su - Marlborough MA, US

Assignee:

AstraZeneca AB - Sodertalje

International Classification:

A61K 31/498
C07D 413/12
C07D 403/12
C07D 401/12
A61K 31/5377
A61P 35/00
C07D 407/12
C07D 409/12

US Classification:

5142348, 544119, 544353, 544295, 514249

Abstract:

The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.