Vickie Lynn Cooper

US Patent:

7842295, Nov 30, 2010

Filed:

Sep 15, 2008

Appl. No.:

12/210837

Inventors:

Kyoung-Jin Yoon - Ames IA, US
Vickie Cooper - Ames IA, US

Assignee:

Iowa State University Research Foundation, Inc. - Ames IA

International Classification:

A61K 39/12
A61K 39/38
A61K 39/145
A61K 38/16
C12N 7/04
C12N 15/00
C07H 21/02
C07K 16/00
A61K 39/285

US Classification:

4241861, 4241841, 4242041, 4242061, 4242101, 435236, 4353201, 536 231, 530380, 530396

Abstract:

The present invention provides an isolated canine influenza virus of subtype H3N8 comprising an HA having SEQ ID NO: 4 or an amino acid sequence that is greater than 99% identical to SEQ ID NO: 4, with the proviso that the amino acids at positions 94 and 233 are identical to SEQ ID NO: 4; a composition comprising attenuated or inactivated virus; isolated or purified HA, NM, NP, M1, NS1, PA, PB1, and PB2 proteins and fragments thereof and compositions comprising same or nucleic acids, optionally as part of a vector, encoding same; and a method of inducing an immune response to canine influenza virus in an animal comprising administering to the animal an aforementioned composition.

US Patent:

20070098742, May 3, 2007

Filed:

Oct 5, 2006

Appl. No.:

11/539123

Inventors:

Kyoung-Jin Yoon - Ames IA, US
Vickie Cooper - Ames IA, US

Assignee:

IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. - Ames IA

International Classification:

A61K 39/145
C12N 5/06
C12N 15/86
C12N 7/00
C07K 14/11
C07H 21/02

US Classification:

424209100, 435235100, 435456000, 435069300, 435350000, 530350000, 536023720

Abstract:

The present invention provides an isolated canine influenza virus of subtype H3N8 comprising an HA having SEQ ID NO: 4 or an amino acid sequence that is greater than 99% identical to SEQ ID NO: 4, with the proviso that the amino acids at positions 94 and 233 are identical to SEQ ID NO: 4; a composition comprising attenuated or inactivated virus; isolated or purified HA, NM, NP, M1, NS1, PA, PB1, and PB2 proteins and fragments thereof and compositions comprising same or nucleic acids, optionally as part of a vector, encoding same; and a method of inducing an immune response to canine influenza virus in an animal comprising administering to the animal an aforementioned composition.