Vinay K Gupta

US Patent:

6852285, Feb 8, 2005

Filed:

Jul 3, 2001

Appl. No.:

09/898132

Inventors:

Nicholas L. Abbott - Madison WI, US
Justin J. Skaife - Lafayette CA, US
Vinay K. Gupta - Urbana IL, US
Timothy B. Dubrovsky - Flemington NJ, US
Rahul Shah - Davis CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

G01N033/53
G01N027/00

US Classification:

422 8205, 422 55, 422 57, 422 6801, 422 8201, 435 71, 435 74, 436501, 436524, 436528, 436805

Abstract:

Interactions between molecules which are components of self-assembled monolayers and other molecules can be amplified and transduced into an optical signal through the use of a mesogenic layer. The invention provides a device and methods for detecting analytes. The device comprises a substrate onto which a self-assembled monolayer is attached and a mesogenic layer which is anchored by the self-assembled monolayer. The mesogenic layer undergoes a change in conformation in response to the molecular interaction.

US Patent:

6858423, Feb 22, 2005

Filed:

Aug 10, 2000

Appl. No.:

09/637844

Inventors:

Nicholas L. Abbott - Davis CA, US
Justin J. Skaife - Lafayette CA, US
Vinay K. Gupta - Urbana IL, US
Timothy B. Dubrovsky - Flemington NJ, US
Rahul Shah - Davis CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

C12M001/34
C12Q001/68

US Classification:

4352872, 435 4, 435 71, 435 792, 435 74, 435 75, 436 4, 436501

Abstract:

Interactions between molecules which are components of self-assembled monolayers and other molecules can be amplified and transduced into an optical signal through the use of a mesogenic layer. The invention provides a device and methods for detecting analytes. The device comprises a substrate onto which a self-assembled monolayer is attached and a mesogenic layer which is anchored by the self-assembled monolayer. The mesogenic layer undergoes a change in conformation in response to the molecular interaction.

US Patent:

8158005, Apr 17, 2012

Filed:

Nov 3, 2008

Appl. No.:

12/263799

Inventors:

Vinay Gupta - Tampa FL, US
Maya Trotz - Tampa FL, US
Cecil Coutinho - Tampa FL, US

Assignee:

University of South Florida - Tampa FL

International Classification:

C02F 1/28
C02F 1/32

US Classification:

210668, 210669, 210734, 21074814, 210763, 210766

Abstract:

Microcomposites comprising titanium dioxide (TiO2) nanoparticles embedded within cross-linked, thermally responsive microgels of poly(N-isopropylacrylamide) are disclosed. Interpenetrating linear chains of poly(acrylic acid) functionalize the nanoparticles for dispersal within the microgel framework. The microcomposites show rapid sedimentation, which is useful for gravity separation applications such as environmental remediation via photocatalytic degradation. The extent of loading of the TiO2 within the colloidal particles can be easily manipulated from 10% (weight) to a value as high as 75%. The microgel-titania composites showed rapid sedimentation, which is useful for gravity separation of these particles in photocatalytic applications. The settling of the microgel-titania composites occurred over minutes and was much faster than solid, impermeable spheres. As the content of TiO2 increased within the particles from 10% to 75%, the increased effective particle density led to significant decrease in the settling time from approximately 2200 seconds to approximately 100 seconds.

US Patent:

8246911, Aug 21, 2012

Filed:

Jan 9, 2002

Appl. No.:

10/044899

Inventors:

Nicholas L. Abbott - Madison WI, US
Justin J. Skaife - Lafayette CA, US
Vinay K. Gupta - Tampa FL, US
Timothy B. Dubrovsky - Flemington NJ, US
Rahul Shah - Woodburg MN, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

G01N 21/75
G01N 33/53
G01N 27/00
G02F 1/1337
G02F 1/13

US Classification:

422 8205, 422412, 422 8201, 435 71, 435 74, 436501, 436524, 436528, 436805

Abstract:

Interactions between molecules that are components of self-assembled monolayers and other molecules can be amplified and transduced into an optical signal through the use of a mesogenic layer. The invention provides for a method for detecting an analyte, comprising contacting with said analyte a recognition moiety for said analyte, wherein said contacting causes at least a portion of a plurality of mesogens proximate to said recognition moiety to detectably switch from a first orientation to a second orientation upon contacting said analyte with said recognition moiety; and detecting said second orientation of said at least a portion of said plurality of mesogens, whereby said analyte is detected.

US Patent:

20090013609, Jan 15, 2009

Filed:

Oct 29, 2007

Appl. No.:

11/926826

Inventors:

Vinay Gupta - Tampa FL, US
Ashok Kumar - Tampa FL, US
Cecil Coutinho - Tampa FL, US
Subrahmanya Mudhivarthi - Tampa FL, US

Assignee:

UNIVERSITY OF SOUTH FLORIDA - Tampa FL

International Classification:

C09G 1/02
C09K 13/00

US Classification:

51309, 216 89, 51307, 252 791

Abstract:

Organic-inorganic composites were prepared as colloidal particles of a cross-linked, thermally responsive polymer. Hybrid PNIPAM-polysiloxane particles and composite polymeric particles with embedded nanoparticles of an inorganic metal-oxide (MO) such as CeO2 and TiO2 were formed. To promote the incorporation of unaggregated nanoparticles, temperature responsive microspherical gels (microgels) of N-isopropylacrylamide (NIPAM) with interpenetrating (IP) linear chains of poly(acrylic acid) (PAA) were used. The organic-inorganic composition of the hybrid polymer network was controlled by changing the time for condensation and hydrolysis of the siloxane monomer during synthesis. Experimental results indicated that the planarization of silicon oxide wafers using these hybrid particles and composites exhibited lower topographical variations and surface roughness as compared to slurries consisting of only silica or ceria nanoparticles while achieving similar removal rates and better or similar frictional characteristics.

US Patent:

62841971, Sep 4, 2001

Filed:

Jul 31, 1998

Appl. No.:

9/127382

Inventors:

Nicholas L. Abbott - Davis CA
Justin J. Skaife - Lafayette CA
Vinay K. Gupta - Urbana IL
Timothy B. Dubrovsky - Flemington NJ
Rahul Shah - Davis CA

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

G01N 3353
G01N 2700

US Classification:

422 8205

Abstract:

Interactions between molecules which are components of self-assembled monolayers and other molecules can be amplified and transduced into an optical signal through the use of a mesogenic layer. The invention provides a device and methods for detecting analytes. The device comprises a substrate onto which a self-assembled monolayer is attached and a mesogenic layer which is anchored by the self-assembled monolayer. The mesogenic layer undergoes a change in conformation in response to the molecular interaction.

US Patent:

54575362, Oct 10, 1995

Filed:

Apr 4, 1994

Appl. No.:

8/222737

Inventors:

Julia A. Kornfield - Pasadena CA
Vinay Gupta - Pasadena CA
Axel Kratel - Pasadena CA

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

G01J 400

US Classification:

356366

Abstract:

A polarization-modulation scanning laser microscope includes a conventional laser scanning microscope, which has been improved by addition of: a polarization state generator; a polarization state analyzer; a photo-detector for receiving laser light transmitted though a sample; a signal demodulator providing two signals in response to the transmitted laser light, one of the signals being indicative of polarization orientation, and the other signal being indicative of magnitude of the transmitted polarized light. A relay interface toggles between the two signals provided by the signal demodulator and at least one other signal provided either by the photodiode of the laser scanning microscope, or by an external optical beam induced current, or both. A signal processing unit provides an image output to a display device.