A composition, and method for a targeted drug delivery is disclosed in treating central nervous system injury, including blast hearing loss, traumatic brain injury (TBI) and the like, by administering a subject with nanoparticle-based minocycline formulations. The formulation contains nanoparticles encapsulating minocycline for neuroprotective effect in TBI. Albumin nanoparticle-based minocycline formulations provide enhanced delivery to brain, and reduced toxicity at minimal dosage for treating a subject suffering from central nervous system injury including blast induced traumatic brain injury (bTBI). Nanoparticle administered at minimal dose in rat blast TBI model crossed blood-brain barrier (BBB) and enhanced therapeutic concentration compared to free minocycline. Provided is an effective and safe minocycline delivery in TBI with minimal or no toxicity for neuroprotective therapy. Studies indicate performance for behavioral (acute and chronic), pathological (chronic) and hearing loss mitigation using the disclosed drug and nanoparticles in rat moderate bTBI model.
Traction Battery Venting System And Venting Method
- Dearborn MI, US Sumanth Reddy Dadam - New Hudson MI, US Vivek Kumar - Troy MI, US Vinod Ravi - Canton MI, US
International Classification:
H01M 50/317 H01M 10/52 H01M 50/358 B60K 1/04
Abstract:
A traction battery venting system includes, among other things, an engine exhaust system that discharges engine exhaust gas to an area outside an electrified vehicle. The engine exhaust gas is emitted from an internal combustion engine of the electrified vehicle. The system further includes a sound deadening device of the engine exhaust system, a traction battery, and a battery vent system that communicates battery vent byproducts to the engine exhaust system at a position that is downstream from the sound deadening device. The battery vent byproducts are emitted from the traction battery of the electrified vehicle.
- Dearborn MI, US Vinod Ravi - Canton MI, US Di Zhu - Canton MI, US Vivek Kumar - Troy MI, US
International Classification:
F01N 1/16 G10K 11/16
Abstract:
Methods and systems are provided for adjusting a position of an exhaust valve that regulates engine exhaust noise. In one example, the position of the exhaust valve is adjusted according to a distance between a first vehicle and a second vehicle. The exhaust valve may be adjusted to reduce an exhaust noise level when the distance between the first vehicle and the second vehicle is less than a threshold distance.
Engine Oil Dilution Control In Automotive Vehicles
- Dearborn MI, US Vivek Kumar - Troy MI, US Douglas Martin - Canton MI, US Vinod Ravi - Canton MI, US
International Classification:
F01M 5/00 F01M 5/04 F01M 5/02
Abstract:
Methods and systems are provided for controlling engine oil dilution in automotive vehicles. The method comprises heating coolant by operating an exhaust gas heat recovery device and circulating the heated coolant via a first coolant loop between the exhaust gas heat recovery device and a heat exchanger; and heating coolant by operating an exhaust gas recirculation cooler and circulating the heated coolant via a second coolant loop between the exhaust gas recirculation cooler and the heat exchanger, wherein the heated coolant from both the exhaust gas heat recovery device and the exhaust gas recirculation cooler mix at the heat exchanger and allows heating of an engine oil via the heat exchanger. In one example, the method prevents excessive accumulation of water and/or fuel in the engine oil.
Attention-Driven System For Adaptively Streaming Vehicle Sensor Data To Edge Computing And Cloud-Based Network Devices
- Detroit MI, US Sycamore Zhang - Shanghai, CN Shuqing Zeng - Sterling Heights MI, US Kamran Ali - Troy MI, US Vivek Vijaya Kumar - Shelby Township MI, US Donald K. Grimm - Utica MI, US
An attention-driven streaming system includes an adaptive-streaming module and a transceiver. The adaptive-streaming module includes filters, a compression module, an attention-driven strategy module and a fusion module. The filters filter sensor data received from sensors of a vehicle. The compression module compresses the filtered sensor data to generate compressed data. The attention-driven strategy module generates feedforward information based on a state of the vehicle and a state of an environment of the vehicle to adjust a region of interest. The fusion module generates an adaptive streaming strategy to adaptively adjust operations of each of the filters. The transceiver streams the compressed data to at least one of an edge computing device or a cloud-based network device and in response receive feedback information and pipeline monitoring information. The fusion module generates the adaptive streaming strategy based on the feedforward information, the feedback information and the pipeline monitoring information.
A suction assembly, toothbrush, and method are provided that suction fluids and debris resulting from brushing. The suction assembly includes a housing configured to couple to the toothbrush so that a portion extends around sides and a back of the toothbrush head and is spaced from the toothbrush head by a gap. The suction assembly further includes a vacuum pump, a collection reservoir, and one or more conduits that couple the vacuum pump, suction head portion, and collection reservoir to apply a suction around the toothbrush head through the gap and deposit suctioned material in the collection reservoir.
Methods And Systems To Detect And Counter Denial Of Service Attack In Vehicle Communications
- Detroit MI, US Vivek Vijaya Kumar - Shelby Township MI, US Hariharan Krishnan - Troy MI, US Duane S. Carper - Davison MI, US
Assignee:
GM GLOBAL TECHNOLOGY OPERATIONS LLC - Detroit MI
International Classification:
H04L 29/06 H04W 4/40 H04W 4/029 H04K 3/00
Abstract:
A method for detecting and countering denial of service attacks in V2X communication includes providing a vehicle with a wireless communication system including an antenna and providing a controller in communication with the wireless communication system. The method includes receiving a wireless communication, analyzing the wireless communication and determining if a first condition is satisfied. When the first condition is satisfied, the method includes calculating an angle of arrival of the wireless communication, predicting a location of a source of the wireless communication relative to the vehicle, and adjusting a gain pattern of the antenna to block reception of additional wireless communications from the source of the wireless communication.
Methods And Systems For Controlling Lateral Position Of Vehicle Through Intersection
- Detroit MI, US Donald K. Grimm - Utica MI, US Syed Ali - West Bloomfield MI, US Vivek Vijaya Kumar - Shelby Township MI, US
Assignee:
GM GLOBAL TECHNOLOGY OPERATIONS LLC - Detroit MI
International Classification:
G05D 1/02 B60W 30/18 G05D 1/00
Abstract:
Systems and methods are provided for controlling a lateral position of a vehicle through an intersection. The method includes receiving, by a processor, intersection data transmitted by an infrastructure associated with the intersection, the intersection data including at least a position of a plurality of lanes associated with the intersection. The method includes receiving, by the processor, a position of the vehicle, and determining, by the processor, a current lane of travel of the vehicle and a future lane of travel of the vehicle based on the intersection data and the position of the vehicle. The method includes determining, by the processor, a virtual lane through the intersection, the virtual lane providing a path of travel for the vehicle from the current lane of travel to the future lane of travel. The method includes controlling, by the processor, the vehicle based on the virtual lane.
Oct 2011 to 2000 QA Manager/Project Test LeadCOX Communications
Apr 2011 to Sep 2011 Test LeadVerizon Business Alpharetta, GA Aug 2008 to Mar 2011 Test LeadBritish Telecom Ipswich Sep 2005 to Jul 2008 Test Lead/Test Engineer
Education:
Kumaon Engineering College Almora, Uttarakhand 2005 Bachelor of Engineering
Skills:
ETL, Informatica, MS SQL Server 2008, Oracle, Reports and OLAP Cubes using SQL Server Analysis Services(SSAS), Tidal Enterprise Scheduler, PL/SQL, Unix Shell script, C, VBScript, TFS, Quality Center, TOAD, Putty, Rally, VFS , SharePoint
Feb 2013 to 2000 Lead Programmer Analyst - .NetIFC, World Bank Washington, DC Nov 2012 to Feb 2013 Lead .Net DeveloperACE Insurance Salem, VA Oct 2010 to Oct 2012 Sr. .Net DeveloperACE Insurance Philadelphia, PA Apr 2010 to Oct 2010 Sr. .Net DeveloperJPMC Tampa, FL Jan 2009 to Apr 2010 Sr.Net DeveloperP2 Energy Solutions Houston, TX Oct 2007 to Dec 2008 Sr.Net DeveloperDigital River
Jun 2005 to Oct 2007 Net Developer (S. S. ENaval Dockyard, Visakhapattnam
Jun 2004 to Jun 2005 Net DeveloperNaval Dockyard Mumbai, Maharashtra Jan 2004 to Jun 2004 Web Developer
Education:
Sikkim Manipal University Mar 2008 Master of Computer ApplicationsC-DAC Mumbai, Maharashtra Jul 2003 Diploma in Advanced ComputingLucknow University May 2001 Bachelor of Arts
2012 to 2000 Asst. Vice President, Pricing Operate ManagerGenworth Financial Richmond, VA 2009 to 2012 Program ManagerGenworth Financial (Mortgage) Raleigh, NC 2007 to 2008 Asst. Consultant (Sr. Business Analyst)GE Financial Assurance Richmond, VA 2001 to 2006 Sr. Systems AnalystAIG Consultants New York, NY 2000 to 2001 Senior Software EngineerDigerati, Melbourne, Australia
1998 to 1999 Software Engineer
Education:
DUKE UNIVERSITY, The Fuqua School of Business Durham, NC 2012 Master of Business Administration in FinanceKARNATAK UNIVERSITY, BVB College Hubli, Karnataka 1998 Bachelor of Science in Computer Science Engineering
Dr. Kumar graduated from the Lake Erie College of Osteopathic Medicine, Erie Campus in 1997. He works in Ellwood City, PA and 2 other locations and specializes in Cardiovascular Disease. Dr. Kumar is affiliated with Butler Memorial Hospital, Ellwood City Hospital, Lakewood Ranch Medical Center, Manatee Memorial Hospital and UPMC Mercy.
Acute Pancreatitis Anemia Cholelethiasis or Cholecystitis Constipation Diverticulitis
Languages:
English
Description:
Dr. Kumar graduated from the Maulana Azad Med Coll, Delhi Univ, New Delhi, Delhi, India in 2003. He works in Williamsport, PA and specializes in Gastroenterology. Dr. Kumar is affiliated with Williamsport Regional Medical Center.
Management Development Institute - MBA, Shanmugha Arts, Science, Technology & Research Academy - B.Tech, DAV JVM Shyamli - Computer Science, IIPS
Vivek Kumar
Work:
Schenck Rotec India Ltd - Chief of IT & Communiactions (2003) Indian Telephone Industries Ltd - STA (Prog) (1977-1988) Northern Digital Exchanges Ltd - Sr. Engineer (1988-1991) LML Ltd - Asstt Manager (1991-1993) Lohia Machines Ltd - Manager (1993-1999) Migra Electronics Ltd - Consultant (2000-2002)
Education:
Makatpur High School - General Subjects, Giridih College - PCM
About:
While looking back, the first place that I can view is- Giridih (I was born and brought up). I have not been stable yet: from Giridih to New Delhi to Allahabad to Chandigarh to Kanpur and then to Grea...
Bragging Rights:
Studied yet never tried to study!
Vivek Kumar
Work:
Edelman - Senior Account Director (2013) Adfactors PR - Head Servicing: Technology & Services Communications (2004-2013) 20:20 MEDIA (1992-2003)
Education:
The Doon School, Xavier Labour Relations Institute
Vivek Kumar
Work:
MphasiS
Education:
JNV Supaul, DPS Bokaro, AIT Ckm
Tagline:
Corporate Warrior
Vivek Kumar
Work:
IIA
Education:
Ignou - B.sc
About:
I am very practical, and only act after thinking things through. I don't like being forced to answer quickly. I have to evaluate the situation completely. I make decisions based on what I can veri...
Tagline:
I like working and being alone. I like to avoid attention at all costs. I tend to keep to it, and not interact much with the people around me
Bragging Rights:
Survided single
Vivek Kumar
Work:
Microsoft - Support Engineer
Education:
Indira college of commerce and science - Computer (BCA), DAV - 12th, Mount View School - Primary
Vivek Kumar
Work:
Royal Bank of Scotland - Associate (2010) Symphony Services - Senior Product Engineer (2008-2010) Fidelity Investments - Software Engineer (2005-2008)
Education:
Peoples Education Society Institute of Technology - Mechanical Engg.
Vivek Kumar
Work:
Apple Inc. - Marketer (2010) Cognizant Technology Solutions - Software engineer (2010-2011)
Education:
Anna University - IT
Tagline:
I am who I am underneath. But what I do, That defines me. ;) lolz
indows 10 Mail and Calendar will soon provide other features to Gmail users: easily tracking travel and shipping deliveries, making emails more actionable, helping you easily track your favorite sports events, faster search, and more, Vivek Kumar, Microsofts product marketing manager for Windows
Date: Apr 21, 2017
Category: Sci/Tech
Source: Google
Delhi High Court bombing is latest in a string of major attacks
The people collect there, and there is always a crowd, says lawyer Vivek Kumar. He described the scene that morning saying: I felt the tremors [from the bomb]. I saw dust blowing. I saw people running.
Date: Sep 07, 2011
Category: World
Source: Google
Youtube
O re Piya by Taal Tadka
Our Version of O re Piya from the Movie Aaja Nachle. GT Taal Tadka: Sp...
Category:
People & Blogs
Uploaded:
16 Feb, 2010
Duration:
3m 47s
Sathiyaraj Speech - Tamil Stars fast against ...
Leading names of the Tamil film industry, including superstars Rajnika...
Category:
News & Politics
Uploaded:
02 Nov, 2008
Duration:
10m 10s
Ilu Ilu - Vivek Mushran, Dilip Kumar, Manisha...
Watch Ilu Ilu sung by Manhar Udhas, Kavita Krishnamurthy, Sukhwinder S...
Category:
Entertainment
Uploaded:
29 Dec, 2009
Duration:
9m 1s
13- B Trailer
This is the official theatrical trailer for the film 13B. This film is...
Category:
Film & Animation
Uploaded:
30 Jan, 2009
Duration:
1m 22s
Mansoor Ali Khan's mocking speech - Tamil Sta...
Leading names of the Tamil film industry, including superstars Rajnika...
Category:
News & Politics
Uploaded:
02 Nov, 2008
Duration:
7m 15s
Vivek Kumar, IFFLA Patron
Red Carpet interview with another patron from our brand new patron pro...