Vivek A Kumar

US Patent:

20220347193, Nov 3, 2022

Filed:

Apr 27, 2022

Appl. No.:

17/730358

Inventors:

- Newark NJ, US
Arun Reddy Ravula - Newark NJ, US
Namas Chandra - Newark NJ, US
Venkata Kakulavarapu RamaRao - Newark NJ, US
Vivek Kumar - Newark NJ, US
Zain Siddiqui - Paterson NJ, US

Assignee:

New Jersey Institute of Technology - Newark NJ

International Classification:

A61K 31/65
A61K 9/16
A61K 47/60
A61P 27/16
A61P 25/28
A61K 47/69
A61K 47/64

Abstract:

A composition, and method for a targeted drug delivery is disclosed in treating central nervous system injury, including blast hearing loss, traumatic brain injury (TBI) and the like, by administering a subject with nanoparticle-based minocycline formulations. The formulation contains nanoparticles encapsulating minocycline for neuroprotective effect in TBI. Albumin nanoparticle-based minocycline formulations provide enhanced delivery to brain, and reduced toxicity at minimal dosage for treating a subject suffering from central nervous system injury including blast induced traumatic brain injury (bTBI). Nanoparticle administered at minimal dose in rat blast TBI model crossed blood-brain barrier (BBB) and enhanced therapeutic concentration compared to free minocycline. Provided is an effective and safe minocycline delivery in TBI with minimal or no toxicity for neuroprotective therapy. Studies indicate performance for behavioral (acute and chronic), pathological (chronic) and hearing loss mitigation using the disclosed drug and nanoparticles in rat moderate bTBI model.

US Patent:

20210244173, Aug 12, 2021

Filed:

Jun 7, 2019

Appl. No.:

16/972954

Inventors:

- New Brunswick NJ, US
Vivek Ashok Kumar - Newark NJ, US

International Classification:

A46B 15/00
A46B 9/04
A46B 13/02
A46B 5/00
A61C 17/08
A61C 17/12
A61C 17/22

Abstract:

A suction assembly, toothbrush, and method are provided that suction fluids and debris resulting from brushing. The suction assembly includes a housing configured to couple to the toothbrush so that a portion extends around sides and a back of the toothbrush head and is spaced from the toothbrush head by a gap. The suction assembly further includes a vacuum pump, a collection reservoir, and one or more conduits that couple the vacuum pump, suction head portion, and collection reservoir to apply a suction around the toothbrush head through the gap and deposit suctioned material in the collection reservoir.

US Patent:

20180308015, Oct 25, 2018

Filed:

Apr 19, 2018

Appl. No.:

15/957607

Inventors:

Vivek Ashok Kumar - Newark NJ, US
Vinicius Frigatti - Harrison NJ, US
Christopher Magesty - Kearny NJ, US
Jasper Davey - Bloomfield NJ, US
Dhruv Shah - Piscataway NJ, US
Peter Nguyen - New Rochelle NY, US

International Classification:

G06Q 10/02

Abstract:

The present disclosure relates to a system and method for soliciting offers and reservations for parking spots. The system and method is, in some instances, embodied as a mobile application that connects users to exchange the current physical space (e.g. parking spaces) in exchange for the same user's or another user's time, money, gratuity or service.

US Patent:

20170172953, Jun 22, 2017

Filed:

Mar 3, 2017

Appl. No.:

15/449119

Inventors:

- HOUSTON TX, US
Vivek Ashok Kumar - Houston TX, US
Abhishek A. Jalan - Houston TX, US

International Classification:

A61K 31/185
C07K 14/00

Abstract:

A composition and system for delivering a therapeutic agent is provided. The composition includes a self-assembling peptide ionically cross-linked with a charged therapeutic agent. In the presence of the charged therapeutic agent, the peptide self-assembles to form a nanofibrous hydrogel scaffold, wherein the hydrogel structure is quickly recoverable following a shear stress thereby permitting administration of the composition by syringe-needle or catheter injection. Methods of using the composition is also provided.

US Patent:

20140193477, Jul 10, 2014

Filed:

Oct 11, 2013

Appl. No.:

14/052581

Inventors:

- Atlanta GA, US
- Boston MA, US
Vivek Ashok Kumar - Houston TX, US
Adam W. Martinez - Decatur GA, US

Assignee:

Emory University - Atlanta GA
Beth Israel Deaconess Medical Center, Inc. - Boston MA

International Classification:

A61L 27/44
A61L 27/54
A61L 27/24

US Classification:

424443, 530356, 514773, 424 931, 424549, 424602, 428221, 428220

Abstract:

This disclosure relates to materials fabricated from collagen and uses relates thereto. Typically, layers of collagen are stretched during a curing period and optionally coated or impregnated with an elastin like protein. In certain embodiments, these materials can be used in tissue repair or arranged into cylinders and utilized as a prosthetic vascular graft.