Wei Qin Huang

US Patent:

8522664, Sep 3, 2013

Filed:

Oct 31, 2011

Appl. No.:

13/285049

Inventors:

Yun Chen - Clarksburg MD, US
Wei Huang - Clarksburg MD, US
Haoxing Chen - Clarksburg MD, US

International Classification:

F41H 5/02
F41H 7/00
F41H 1/00

US Classification:

89 3602, 89 3605, 2 25

Abstract:

An apparatus for providing protection from blast and ballistic energy is provided. The apparatus includes a liquid storage mechanism containing a liquid and a rigid layer internal to the liquid storage mechanism. The apparatus also includes a pressure release mechanism configured to allow the liquid to exit the liquid storage mechanism when a pressure sufficient to open or activate the pressure release mechanism contacts the liquid storage mechanism and presses the liquid storage mechanism against the rigid layer.

US Patent:

20020049193, Apr 25, 2002

Filed:

Aug 10, 2001

Appl. No.:

09/925630

Inventors:

Gregory Hamilton - Catonsville MD, US
Wei Huang - Wildwood MO, US

Assignee:

GPI NIL HOLDINGS, INC. - Wilmington DE

International Classification:

A61K031/553
A61K031/554
A61K031/54
A61K031/55

US Classification:

514/211010, 514/212010, 514/219000, 514/227500, 514/237500, 514/255010, 514/330000, 514/365000, 514/374000, 514/385000, 514/423000, 548/200000, 548/236000, 548/322500, 548/530000, 546/225000, 544/386000, 544/158000, 544/058400, 540/604000, 540/575000, 540/488000

Abstract:

This invention relates to neurotrophic low molecular weight, small molecule N-linked sulfonamides of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.

US Patent:

20020049199, Apr 25, 2002

Filed:

Jun 21, 2001

Appl. No.:

09/885178

Inventors:

Gregory Hamilton - Catonsville MD, US
Jia-He Li - Cockeysville MD, US
Wei Huang - Chesterfield MO, US

International Classification:

A61K031/55
A61K031/445
A61K031/401
C07D211/60
C07D207/267
C07D223/04

US Classification:

514/217110, 514/330000, 514/365000, 514/375000, 514/385000, 514/423000, 540/607000, 546/245000, 548/553000

Abstract:

This invention relates to neurotrophic low molecular weight, small molecule N-linked ureas and carbamates of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.

US Patent:

20070204879, Sep 6, 2007

Filed:

Mar 1, 2007

Appl. No.:

11/712862

Inventors:

Yun Chen - Germantown MD, US
Wei Huang - Germantown MD, US

International Classification:

A61C 15/00

US Classification:

132325

Abstract:

A handle houses a dental floss supply reel and a dental floss take-up reel in separate chambers. Movement and tension of a single long strand of dental floss through a pair of arched flossing arms is controlled by a new dental floss supply control knob, and a used dental floss take-up control knob. Spring loaded ratchets control the action of the reels. A hygienic cover protects the flossing arms. A small brush stored in the cover cleans the used dental floss of debris.

US Patent:

20100147749, Jun 17, 2010

Filed:

Dec 10, 2009

Appl. No.:

12/635145

Inventors:

Pascal Tromeur - Wilmington DE, US
Pavol Pranda - Hockessin DE, US
Wei Huang - Newark DE, US
Jingguang G. Chen - Hockessin DE, US

Assignee:

American Air Liquide, Inc. - Fremont CA

International Classification:

C10G 29/16
B01J 23/56
B01J 23/755
B01J 23/89
B01J 23/75

US Classification:

208244, 502326, 502330, 502337

Abstract:

The present invention relates to multi-metallic catalyst compositions for improved coke resistance in a hydrocarbon feed pre-reformer unit that comprises nickel and an enhancing component selected from at least one member of the group consisting of ruthenium, palladium, platinum, rhodium, cobalt, gold and silver on a support. The present invention further relates to a catalyst system for improved coke and sulfur resistance in a hydrocarbon feed pre-reformer unit that comprises at least one multi-metallic catalyst composition comprising nickel and an enhancing component selected from at least one member of the group consisting of ruthenium, palladium, platinum, rhodium, cobalt, gold and silver on a support used in conjunction with at least one sulfur capturing component selected from the group comprising copper oxide and zinc oxide. Finally the present invention relates to the use of this catalyst system in a process for pre-reforming a hydrocarbon feed stream.

US Patent:

20120226024, Sep 6, 2012

Filed:

Mar 5, 2012

Appl. No.:

13/411733

Inventors:

LAI-XI WANG - ELLICOTT CITY MD, US
WEI HUANG - DUNDALK MD, US
JOHN GIDDENS - CHESAPEAKE VA, US

International Classification:

C12P 21/06
C07K 16/00
C12P 21/08

US Classification:

5303873, 435 681

Abstract:

A chemoenzymatic method for the preparation of a core-fucoslyated glycoprotein or glycopeptide, including (a) providing an acceptor selected from the group consisting of a fucosylated GlcNAc-protein and fucosylated GlcNAc-peptide; and (b) reacting the acceptor with a donor substrate including an activated oligosaccharide moiety, in the presence of an endoglycosidase (ENGase) selected from Endo;F1, Endo-F2, Endo-F3, Endo-D and related glycosynthase mutants to transfer the oligosaccharide moiety to the acceptor and yield the structure defined core-fucosylated glycoprotein or glycopeptide. The donor substrate includes, in a specific implementation, a synthetic oligosaccharide oxazoline. A related method of fucosylated glycoprotein or fucosylated glycopeptide remodeling with a predetermined natural N-glycan or a tailor-made oligosaccharide moiety, and a method of remodeling an antibody to include a predetermined sugar chain to replace a heterogeneous sugar chain, are also described.

US Patent:

58744495, Feb 23, 1999

Filed:

Dec 31, 1996

Appl. No.:

8/775584

Inventors:

Gregory S. Hamilton - Catonsville MD
Jia-He Li - Cockeysville MD
Wei Huang - Baltimore MD

Assignee:

GPI NIL Holdings, Inc. - Wilmington DE

International Classification:

A61K 3140
A61K 31445
C07D20748
C07D21196

US Classification:

514330

Abstract:

This invention relates to neurotrophic low molecular weight, small molecule N-linked sulfonamides of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.

US Patent:

59589493, Sep 28, 1999

Filed:

Dec 23, 1997

Appl. No.:

8/997451

Inventors:

Gregory S. Hamilton - Catonsville MD
Jia-He Li - Cockeysville MD
Wei Huang - Chesterfield MO

Assignee:

GPI NIL Holdings Inc. - Wilmington DE

International Classification:

A61K 31445
C07D40112

US Classification:

514318

Abstract:

This invention relates to neurotrophic low molecular weight, small molecule N-linked ureas and carbamates of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.