Wei Hua Sophie Li

US Patent:

6906067, Jun 14, 2005

Filed:

Jun 26, 2001

Appl. No.:

09/891750

Inventors:

Kevin Joseph Moriarty - Norristown PA, US
Yvonne Shimshock - Hillsborough NJ, US
Gulzar Ahmed - Yardley PA, US
Junjun Wu - Malden MA, US
James Wen - Dayton NJ, US
Wei Li - Acton MA, US
Shawn David Erickson - Leonia NJ, US
Jeffrey John Letourneau - East Windsor NJ, US
Edward McDonald - Banstead, GB
Katerina Leftheris - Skillman NJ, US
Stephen T. Wrobleski - Whitehouse Station NJ, US
Zahid Hussain - Monmouth Junction NJ, US
Ian Henderson - Hopewell NJ, US
Axel Metzger - East Windsor NJ, US
John J. Baldwin - Gwynedd Valley PA, US
Alaric J. Dyckman - Lawrenceville NJ, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ
Pharmaceopeia, Inc. - Cranbury NJ

International Classification:

C07D251/40
C07D251/48
C07D251/52
A61K031/53
A61P035/00

US Classification:

514241, 544197, 544198, 544208, 544209, 544213, 544217, 544218

Abstract:

N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula I: Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-α expression utilizing compounds of the present invention are also disclosed.

US Patent:

6984735, Jan 10, 2006

Filed:

Nov 26, 2003

Appl. No.:

10/722782

Inventors:

John C. McKew - Arlington MA, US
Steven Y. Tam - Wellesley MA, US
Katherine L. Lee - West Newton MA, US
Lihren Chen - Cambridge MA, US
Paresh Thakker - Boston MA, US
Fuk-Wah Sum - Pomona NY, US
Mark Behnke - Sommerville MA, US
Baihua Hu - Audubon PA, US
James D. Clark - Acton MA, US
Wei Li - Acton MA, US

Assignee:

Wyeth - Madison NJ

International Classification:

C07D 215/38
C07D 217/12

US Classification:

544334, 546146, 546169, 546315, 548194, 548236, 548248, 568316

Abstract:

A process for making an aromatic aldehyde in which a sulfoxide is reacted with a dihalogenated aromatic compound in the absence of an effective amount of an activating reagent. The aldehyde may then be used to make other compounds, such as a compound that acts as a cPLA inhibitor.

US Patent:

7346152, Mar 18, 2008

Filed:

Oct 14, 2004

Appl. No.:

10/965419

Inventors:

Jonathan Paden - Austin TX, US
Bobby Sams - Austin TX, US
Kurt M. Joseph - Austin TX, US
Wei Li - Yorktown Heights NY, US

Assignee:

SBC Knowledge Ventures, L.P. - Reno NV

International Classification:

H04M 11/00

US Classification:

379 8816, 707 3

Abstract:

A method for an automated voice response system to present access numbers to dial-up Internet users. The automated voice response system can perform the step of establishing a telephony communication with a party responsive to a received telephone call from the party. An indicator a service region within which dial-up Internet access is requested can be received by the automated voice response system. At least one data store can be queried for access numbers associated with the service region. A response to the querying step can be dynamically generated. The generated response can be customized specifically for the telephony communication. When the response includes at least one access number, the included access number or numbers can be presented to the party across the telephone communication.

US Patent:

7420001, Sep 2, 2008

Filed:

Dec 1, 2004

Appl. No.:

11/001589

Inventors:

Jeremy Ian Levin - New City NY, US
Frank Lovering - Acton MA, US
Yonghan Hu - Burlington MA, US
Jianchang Li - Carlisle MA, US
Wei Li - Acton MA, US
Jun Jun Wu - Arlington MA, US
Rajeev Hotchandani - Somerville MA, US
Jason Shaoyun Xiang - Winchester MA, US
Xuemei Du - Valley Cottage NY, US
Derek Cecil Cole - New City NY, US
Steve Yikkai Tam - Wellesley MA, US

Assignee:

Wyeth - Madison NJ

International Classification:

A61K 31/343
C07D 307/81

US Classification:

514469, 514470, 549466, 549467

Abstract:

The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.

US Patent:

7479495, Jan 20, 2009

Filed:

Jun 2, 2005

Appl. No.:

11/143430

Inventors:

Kevin Joseph Moriarty - Norristown PA, US
Yvonne Shimshock - Hillsborough NJ, US
Gulzar Ahmed - Yardley PA, US
Junjun Wu - Malden MA, US
James Wen - Dayton NJ, US
Wei Li - Acton MA, US
Shawn David Erickson - Leonia NJ, US
Jeffrey John Letourneau - East Windsor NJ, US
Edward McDonald - Banstead, GB
Katerina Leftheris - Skillman NJ, US
Stephen T. Wrobleski - Whitehouse Station NJ, US
Zahid Hussain - Monmouth Junction NJ, US
Ian Henderson - Hopewell NJ, US
Axel Metzger - East Windsor NJ, US
John J. Baldwin - Gwynedd Valley PA, US
Alaric J. Dyckman - Lawrenceville NJ, US

Assignee:

Pharmacopeia, Inc. - Cranbury NJ
Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C07D 239/32
C07D 239/48
C07D 239/50
C07D 401/04
C07D 401/12
C07D 403/04
C07D 403/12
A61K 31/505
A61K 31/506
A61P 19/02
A61P 35/00

US Classification:

514269, 514272, 514273, 514275, 544317, 544320, 544321, 544323, 544326

Abstract:

N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula I:Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-α expression utilizing compounds of the present invention are also disclosed.

US Patent:

7571159, Aug 4, 2009

Filed:

Feb 1, 2006

Appl. No.:

11/344193

Inventors:

Shiby Thomas - Nashua NH, US
Wei Li - San Carlos CA, US
Joseph Yarmus - Groton MA, US
Mahesh Jagannath - Shrewsbury MA, US
Ari W. Mozes - Lexington MA, US

Assignee:

Oracle International Corporation - Redwood Shores CA

International Classification:

G06F 7/00
G06F 17/30
G06F 17/00

US Classification:

707 3, 7071041

Abstract:

A method, system, and computer program product for counting predictor-target pairs for a decision tree model provides the capability to generate count tables that is quicker and more efficient than previous techniques. A method of counting predictor-target pairs for a decision tree model, the decision tree model based on data stored in a database, the data comprising a plurality of rows of data, at least one predictor and at least one target, comprises generating a bitmap for each split node of data stored in a database system by intersecting a parent node bitmap and a bitmap of a predictor that satisfies a condition of the node, intersecting each split node bitmap with each predictor bitmap and with each target bitmap to form intersected bitmaps, and counting bits of each intersected bitmap to generate a count of predictor-target pairs.

US Patent:

7605156, Oct 20, 2009

Filed:

May 27, 2005

Appl. No.:

11/140390

Inventors:

John C. McKew - Arlington MA, US
Steve Y. Tam - Wellesley MA, US
Katherine L. Lee - West Newton MA, US
Lihren Chen - Cambridge MA, US
Paresh Thakker - Boston MA, US
Fuk-Wah Sum - Pomona NY, US
Mark L. Behnke - Somerville MA, US
Baihua Hu - Audubon PA, US
James D. Clark - Acton MA, US
Wei Li - Acton MA, US
Valerie Clerin - Watertown MA, US
Suzana Marusic - Reading MA, US
Kevin Pong - Robbinsville NJ, US

Assignee:

Wyeth - Madison NJ

International Classification:

A61K 31/54

US Classification:

5142282, 514374, 514375, 514381, 514386, 514406, 514414, 5142335, 51425409, 514256, 514365, 514339, 514345, 544 582, 544143, 544333, 544373, 546 16, 546201, 5462774, 546115

Abstract:

This invention provides methods for the use of substituted indole compounds of the general formula:.

US Patent:

7632838, Dec 15, 2009

Filed:

Feb 7, 2007

Appl. No.:

11/703522

Inventors:

Jason Shaoyun Xiang - Winchester MA, US
Eddine Saiah - Brookline MA, US
Steve Y. Tam - Wellesley MA, US
John C. Mckew - Arlington MA, US
Lihren Chen - Bedford MA, US
Manus Ipek - Watertown MA, US
Jianchang Li - Carlisle MA, US
Wei Li - Acton MA, US
Tarek Suhayl Mansour - New City NY, US
Vipin Suri - Waltham MA, US
Yuchuan Wu - Acton MA, US
Jinbo Lee - Andover MA, US
Eva Binnun - Boston MA, US
Douglas P. Wilson - Ayer MA, US

Assignee:

Wyeth - Madison NJ

International Classification:

A61K 31/4965
C07D 241/04
C07D 295/00

US Classification:

51425503, 544383

Abstract:

This invention relates to inhibiting 11βHSD1.