Wei D Li

US Patent:

6984735, Jan 10, 2006

Filed:

Nov 26, 2003

Appl. No.:

10/722782

Inventors:

John C. McKew - Arlington MA, US
Steven Y. Tam - Wellesley MA, US
Katherine L. Lee - West Newton MA, US
Lihren Chen - Cambridge MA, US
Paresh Thakker - Boston MA, US
Fuk-Wah Sum - Pomona NY, US
Mark Behnke - Sommerville MA, US
Baihua Hu - Audubon PA, US
James D. Clark - Acton MA, US
Wei Li - Acton MA, US

Assignee:

Wyeth - Madison NJ

International Classification:

C07D 215/38
C07D 217/12

US Classification:

544334, 546146, 546169, 546315, 548194, 548236, 548248, 568316

Abstract:

A process for making an aromatic aldehyde in which a sulfoxide is reacted with a dihalogenated aromatic compound in the absence of an effective amount of an activating reagent. The aldehyde may then be used to make other compounds, such as a compound that acts as a cPLA inhibitor.

US Patent:

7571301, Aug 4, 2009

Filed:

Mar 31, 2006

Appl. No.:

11/395841

Inventors:

Arun Kejariwal - Irvine CA, US
Hideki Saito - Sunnyvale CA, US
Xinmin Tian - Union City CA, US
Milind Girkar - Sunnyvale CA, US
Sanjiv Shah - Champaign IL, US
Wei Li - Redwood City CA, US
Utpal Banerjee - Fremont CA, US

Assignee:

Intel Corporation - Santa Clara CA

International Classification:

G06F 9/45
G06F 9/52

US Classification:

712215, 717150

Abstract:

A method for improving parallel processing of computer programs. DOACROSS loops and similar code are identified and parallelized using a post-wait control structure. The post-wait control structure may be implemented to include any one of a single counter to enforce an order of execution, an array to track code completion that is indexed by a modulus of a positive integer number, and/or a set of arrays to track a last code completed by a thread and a current code being executed by a thread.

US Patent:

7605156, Oct 20, 2009

Filed:

May 27, 2005

Appl. No.:

11/140390

Inventors:

John C. McKew - Arlington MA, US
Steve Y. Tam - Wellesley MA, US
Katherine L. Lee - West Newton MA, US
Lihren Chen - Cambridge MA, US
Paresh Thakker - Boston MA, US
Fuk-Wah Sum - Pomona NY, US
Mark L. Behnke - Somerville MA, US
Baihua Hu - Audubon PA, US
James D. Clark - Acton MA, US
Wei Li - Acton MA, US
Valerie Clerin - Watertown MA, US
Suzana Marusic - Reading MA, US
Kevin Pong - Robbinsville NJ, US

Assignee:

Wyeth - Madison NJ

International Classification:

A61K 31/54

US Classification:

5142282, 514374, 514375, 514381, 514386, 514406, 514414, 5142335, 51425409, 514256, 514365, 514339, 514345, 544 582, 544143, 544333, 544373, 546 16, 546201, 5462774, 546115

Abstract:

This invention provides methods for the use of substituted indole compounds of the general formula:.

US Patent:

7629797, Dec 8, 2009

Filed:

Apr 5, 2007

Appl. No.:

11/697060

Inventors:

Yu-Chong Tai - Pasadena CA, US
Chi-yuan Shih - Pasadena CA, US
Wei Li - Monterey Park CA, US
Siyang Zheng - Pasadena CA, US

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

G01R 27/26

US Classification:

324684, 324686, 324663, 324664

Abstract:

Methods and systems for improving the sensitivity of a variety of conductivity sensing devices, in particular capacitively-coupled contactless conductivity detectors. A parallel inductor is added to the conductivity sensor. The sensor with the parallel inductor is operated at a resonant frequency of the equivalent circuit model. At the resonant frequency, parasitic capacitances that are either in series or in parallel with the conductance (and possibly a series resistance) is substantially removed from the equivalent circuit, leaving a purely resistive impedance. An appreciably higher sensor sensitivity results. Experimental verification shows that sensitivity improvements of the order of 10,000-fold are possible. Examples of detecting particulates with high precision by application of the apparatus and methods of operation are described.

US Patent:

7632838, Dec 15, 2009

Filed:

Feb 7, 2007

Appl. No.:

11/703522

Inventors:

Jason Shaoyun Xiang - Winchester MA, US
Eddine Saiah - Brookline MA, US
Steve Y. Tam - Wellesley MA, US
John C. Mckew - Arlington MA, US
Lihren Chen - Bedford MA, US
Manus Ipek - Watertown MA, US
Jianchang Li - Carlisle MA, US
Wei Li - Acton MA, US
Tarek Suhayl Mansour - New City NY, US
Vipin Suri - Waltham MA, US
Yuchuan Wu - Acton MA, US
Jinbo Lee - Andover MA, US
Eva Binnun - Boston MA, US
Douglas P. Wilson - Ayer MA, US

Assignee:

Wyeth - Madison NJ

International Classification:

A61K 31/4965
C07D 241/04
C07D 295/00

US Classification:

51425503, 544383

Abstract:

This invention relates to inhibiting 11βHSD1.

US Patent:

7906548, Mar 15, 2011

Filed:

Aug 11, 2009

Appl. No.:

12/539074

Inventors:

John C. McKew - Arlington MA, US
Steve Y. Tam - Wellesley MA, US
Katherine L. Lee - West Newton MA, US
Lihren Chen - Cambridge MA, US
Paresh Thakker - Boston MA, US
Fuk-Wah Sum - Pomona NY, US
Mark L. Behnke - Somerville MA, US
Baihua Hu - Audubon PA, US
James D. Clark - Acton MA, US
Wei Li - Acton MA, US
Valerie Clerin - Watertown MA, US
Suzana Marusic - Reading MA, US
Kevin Pong - Robbinsville NJ, US

Assignee:

Wyeth LLC - Madison NJ

International Classification:

A01N 43/38

US Classification:

514415

Abstract:

This invention provides methods for the use of substituted indole compounds of the general formula:.

US Patent:

8163736, Apr 24, 2012

Filed:

Jul 16, 2008

Appl. No.:

12/174195

Inventors:

Laurence Gauzy - Paris, FR
Herve Bouchard - Thiais, FR
Ravi V. J. Chari - Newton MA, US
Alain Commercon - Vitry-sur-Seine, FR
Robert Zhao - Lexington MA, US
Yonghong Deng - Arlington MA, US
Wei Li - Winchester MA, US

Assignee:

sanofi-aventis - Paris

International Classification:

C07D 519/00
C07D 487/00
A61K 31/5517

US Classification:

514220, 540496

Abstract:

The present invention is related to new tomaymycin derivatives, their process of preparation and their therapeutic uses.

US Patent:

8299106, Oct 30, 2012

Filed:

Sep 5, 2008

Appl. No.:

12/676869

Inventors:

Chiang Jia Li - Cambridge MA, US
Youzhi Li - Westwood MA, US
Wei Li - Wayland MA, US
Harry Rogoff - Wrentham MA, US

Assignee:

Boston Biomedical, Inc. - Norwood MA

International Classification:

A01N 43/78
A61K 31/425

US Classification:

514365

Abstract:

The present invention relates to novel thiazole-substituted indolin-2-ones as inhibitors of CSCPK and related kinases; to methods of inhibiting cancer stem cells by using a kinase inhibitor; to pharmaceutical compositions containing such compounds; and to methods of using such compounds in the treatment of a protein kinase related disorder in a mammal; and to processes of making such compounds and intermediates thereof.