Wendy S Rubinstein

US Patent:

20100292093, Nov 18, 2010

Filed:

Oct 17, 2008

Appl. No.:

12/682176

Inventors:

Wendy S. Rubinstein - Skokie IL, US

International Classification:

C40B 30/04

US Classification:

506 9

Abstract:

This invention relates to the identification and use of gene expression profiles, patterns, suitable for the identification of breast cancer patient populations with an inherited predisposition to breast and ovarian cancer. The gene expression patterns may be embodied in nucleic acid expression, protein expression, or other expression formats and may be used in the study and/or determination of optimal treatment, cancer prevention, patient and family identification, and other uses. The invention also pertains to the identification of patients with sporadic breast cancer, where a similar biology to that of hereditary breast cancer is caused by alternative mechanisms such as epigenetic modification of BRCA1 or somatic mutation of other genes.