Wenlang Fu from Florham Park, NJ, age 55

Us Patents

Pyrimidine Derivatives For Treatment Of Hyperproliferative Disorders
view source
US Patent:

7582645, Sep 1, 2009
Filed:

Oct 8, 2004
Appl. No.:

10/573227
Inventors:

Julie A. Dixon - Bethany CT, US
Dhanapalan Nagarathnam - Bethany CT, US
Lei Zhang - Hamden CT, US
Chunguang Wang - Hamden CT, US
Lin Yi - Milford CT, US
Yuanwei Chen - North Haven CT, US
Jianqing Chen - New Haven CT, US
Brian Bear - Oceanside CA, US
Michael Brands - Wuppertal, DE
Alexander Hillisch - Velbert, DE
Donald Bierer - Bethany CT, US
Ming Wang - Milford CT, US
Wenlang Fu - Milford CT, US
Martin F. Hentemann - Hamden CT, US
Ann-Marie Bullion - Milford CT, US
Assignee:

Bayer Pharmaceuticals Corporation - West Haven CT
International Classification:

C07D 239/48
C07D 401/12
C07D 401/14
C07D 403/12
C07D 403/14
C07D 409/14
C07D 413/14
A61K 31/506
A61K 31/505
A61P 35/00
US Classification:

514269, 514275, 544323, 544324, 544326, 544328, 544329
Abstract:

Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R, G, G′, and G″ represent substituent groups and Rrepresents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.

Pyrimidine Derivatives For Treatment Of Hyperproliferative Disorders
view source
US Patent:

7582646, Sep 1, 2009
Filed:

Mar 10, 2005
Appl. No.:

11/078681
Inventors:

Julie A. Dixon - Bethany CT, US
Dhanapalan Nagarathnam - Bethany CT, US
Lei Zhang - Hamden CT, US
Chunguang Wang - Hamden CT, US
Lin Yi - Milford CT, US
Yuanwei Chen - North Haven CT, US
Jianqing Chen - New Haven CT, US
Brian R. Bear - Oceanside CA, US
Michael Brands - Hamden CT, US
Alexander Hillisch - Velbert, DE
Donald Bierer - Bethany CT, US
Ming Wang - Milford CT, US
Wenlang Fu - Milford CT, US
Martin F. Hentemann - Hamden CT, US
Ann-Marie Bullion - Milford CT, US
Manoj Patel - Berlin CT, US
Assignee:

Bayer Pharmaceuticals Corporation - West Haven CT
International Classification:

C07D 239/48
C07D 401/12
C07D 401/14
C07D 403/12
C07D 403/14
C07D 409/14
C07D 413/14
A61K 31/505
A61K 31/506
A61P 35/00
US Classification:

514269, 514275, 544323, 544324, 544326, 544328, 544329
Abstract:

Pyrimidine derivatives of formula (I).

Pyrimidine Derivatives For Treatment Of Hyperproliferative Disorders
view source
US Patent:

7678804, Mar 16, 2010
Filed:

Mar 10, 2005
Appl. No.:

11/078681
Inventors:

Julie A. Dixon - Bethany CT, US
Dhanapalan Nagarathnam - Bethany CT, US
Lei Zhang - Hamden CT, US
Chunguang Wang - Hamden CT, US
Lin Yi - Milford CT, US
Yuanwei Chen - North Haven CT, US
Jianqing Chen - New Haven CT, US
Brian R. Bear - Oceanside CA, US
Michael Brands - Hamden CT, US
Alexander Hillisch - Velbert, DE
Donald Bierer - Bethany CT, US
Ming Wang - Milford CT, US
Wenlang Fu - Milford CT, US
Martin F. Hentemann - Hamden CT, US
Ann-Marie Bullion - Milford CT, US
Manoj Patel - Berlin CT, US
Assignee:

Bayer Healthcare LLC - Tarrytown NY
International Classification:

C07D 239/48
C07D 401/12
C07D 401/14
C07D 403/12
C07D 403/14
C07D 409/14
C07D 413/14
A61K 31/505
A61K 31/506
A61P 35/00
US Classification:

514269, 514275, 544323, 544324, 544326, 544328, 544329
Abstract:

Pyrimidine derivatives of formula (I).

Pyrrolotriazine Derivatives Useful For Treating Hyper-Proliferative Disorders And Diseases Associated With Angiogenesis
view source
US Patent:

8338595, Dec 25, 2012
Filed:

Jul 20, 2009
Appl. No.:

12/506033
Inventors:

Julie A. Dixon - Bethany CT, US
Catherine Brennan - Durham NC, US
Karl Miranda - Lexington MA, US
Brent Chandler - New Haven CT, US
Barton Phillips - New Haven CT, US
Jianmei Fan - Newton MA, US
Michael Brands - Wuppertal, DE
Andrea McClure - West Haven CT, US
Benjamin D. Jones - New Haven CT, US
Wenlang Fu - Milford CT, US
Donald Bierer - Bethany CT, US
Steven Magnuson - Wallingford CT, US
Harold C. E. Kluender - Trumbull CT, US
Assignee:

Bayer HealthCare LLC - Tarrytown NY
International Classification:

C07D 487/04
C07D 417/02
C07D 413/02
A61K 31/53
A61P 35/00
US Classification:

544183, 514243, 5142278, 5142315, 544 60, 544111
Abstract:

This invention relates to pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.

3-Pyridyl Or 4-Isoquinolinyl Thiazoles As C17, 20 Lyase Inhibitors
view source
US Patent:

20040267017, Dec 30, 2004
Filed:

Mar 26, 2004
Appl. No.:

10/490822
Inventors:

Donald Bierer - Bethany CT, US
Jeffrey Johnson - Branford CT, US
Gaetan Ladouceur - Guilford CT, US
William Scott - Guilford CT, US
Andrea McClure - West Haven CT, US
Wenlang Fu - Hamden CT, US
Furahi Achebe - West Haven CT, US
Michael Burke - New Haven CT, US
Chen Bi - West Haven CT, US
Barry Hart - Palo Alto CA, US
International Classification:

C 07D 4 3/02
C07D233/70
US Classification:

544/370000, 548/322500
Abstract:

The invention provides novel thiazoles bearing 3-pyridyl or 4-isoquinilinyl substituents, and pharmaceutical compositions thereof. The invention also provides methods of using compounds of the invention and pharmaceutical compositions thereof as inhibitors of lyases, e.g., the 17a-hydroxylase-C17,20 enzyme. The invention further provides methods for treating cancer in a subject, comprising administering to the subject a compound of the invention or a pharmaceutical composition thereof. The cancer can be, e.g., prostate cancer or breast cancer.

Pyrrolotriazine Derivatives Useful For Treating Hyper-Proliferative Disorders And Diseases Associated With Angiogenesis
view source
US Patent:

20070208013, Sep 6, 2007
Filed:

Jun 3, 2005
Appl. No.:

11/596913
Inventors:

Julie Dixon - Bethany CT, US
Catherine Brennan - Durham NC, US
Karl Miranda - Lexington MA, US
Brent Chandler - New Haven CT, US
Barton Phillips - New Haven CT, US
Jianmei Fan - Newton MA, US
Michael Brands - Hamden CT, US
Andrea Mcclure - West Haven CT, US
Benjamin Jones - New Haven CT, US
Wenlang Fu - Milford CT, US
Donald Bierer - Bethany CT, US
Steven Magnuson - Wallingford CT, US
Harold Kluender - Trumbull CT, US
Assignee:

BAYER PHARMACEUTICALS CORPORATION - West Haven CT
International Classification:

A61K 31/541
A61K 31/5377
A61K 31/53
C07D 487/04
US Classification:

514227800, 514234200, 514243000, 544060000, 544112000, 544183000
Abstract:

This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.

Pyrimidine Derivatives
view source
US Patent:

20090258888, Oct 15, 2009
Filed:

Apr 7, 2006
Appl. No.:

11/918016
Inventors:

Dhanapalan Nagarathnam - Bethany CT, US
Yuanwei Chen - North Haven CT, US
Wenlang Fu - Milford CT, US
Donald Bierer - Bethany CT, US
Ming Wang - Belle Mead NJ, US
Michael Brands - Wuppertal, DE
Yamin Wang - Sandy Hook CT, US
Brian R. Bear - Oceanside CA, US
Aaron Schmitt - Hamden CT, US
Eric Mull - Guilford CT, US
David Miller - Waltham MA, US
Jin Zhao - Natick MA, US
Assignee:

Bayer Pharmaceuticals Corporation - West Haven CT
International Classification:

A61K 31/506
C07D 239/46
A61P 35/00
US Classification:

514275, 544297
Abstract:

This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.

Pyrimidine Derivatives
view source
US Patent:

20090286785, Nov 19, 2009
Filed:

Apr 7, 2006
Appl. No.:

11/887976
Inventors:

Dhanapalan Nagarathnam - Bethany CT, US
Yuanwei Chen - North Haven CT, US
Wenlang Fu - Milford CT, US
Donald Bierer - Bethany CT, US
Ming Wang - Milford CT, US
Michael Brands - Wuppertal, DE
Yamin Wang - Sandy Hook CT, US
Brian R. Bear - Oceanside CA, US
Assignee:

Bayer Pharmaceuticals Corporation - West Haven CT
International Classification:

A61K 31/5377
C07D 413/14
A61P 35/00
C07D 401/14
A61K 31/506
US Classification:

5142352, 544122, 544324, 514275
Abstract:

This invention relates to novel compounds (I) and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.