Wiktor A Janczewski

US Patent:

20110218190, Sep 8, 2011

Filed:

Nov 9, 2009

Appl. No.:

13/128326

Inventors:

Walter E. Babiec - Palos Verdes Peninsula CA, US
Shane A. Saywell - Santa Monica CA, US
Jack L. Feldman - Sherman Oaks CA, US
Wiktor A. Janczewski - Los Angeles CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

A61K 31/549
A61K 31/453
A61K 31/4015
A61P 11/00

US Classification:

5142232, 514321, 514423

Abstract:

The application describes treatment of motoneuronal dysfunctions or disorders using AMPA receptor modulators. Examples of a motoneuronal dysfunction or disorder include obstructive sleep apnea, snoring, multiple sclerosis, spinal cord injury, e.g., crush, partial or complete transection, motor neuron diseases, motor weakness due to aging, stroke, tumor, hemorrhage, degenerative or wasting diseases, and spasticity. One example of an AMPA receptor modulator is a benzothiadiazide compound. Another example of an AMPA receptor modulator is an ampakine. Yet another example of an AMPA receptor modulator is aniracetam.

US Patent:

20170224778, Aug 10, 2017

Filed:

Feb 3, 2017

Appl. No.:

15/424668

Inventors:

- Stanford CA, US
- Oakland CA, US
Kevin Yackle - San Francisco CA, US
Wiktor A. Janczewski - Simi Valley CA, US
Jack Feldman - Los Angeles CA, US

International Classification:

A61K 38/22
A61K 38/10

Abstract:

Activation of neurons in the preBötC with neuromedin B or gastrin releasing peptide increases frequency of sighs.