William T Chiang

US Patent:

8283347, Oct 9, 2012

Filed:

May 28, 2010

Appl. No.:

12/790165

Inventors:

Jiangfeng Fei - White Plains NY, US
William Chiang - Pennington NJ, US
Frank Kerrigan - Wadebridge, GB
Stuart Green - Camelford, GB

Assignee:

Bayer HealthCare LLC - Tarrytown NY

International Classification:

C07D 279/18
A61K 31/5415

US Classification:

5142262, 544 37

Abstract:

A non-leaching mediator may include a compound having the general formula (I):.

US Patent:

20040072282, Apr 15, 2004

Filed:

Jun 23, 2003

Appl. No.:

10/602265

Inventors:

Frank Guarnieri - Princeton NJ, US
John Kulp - Princeton NJ, US
William Chiang - Princeton NJ, US

Assignee:

Sarnoff Corporation

International Classification:

C12P021/06
C07K014/47

US Classification:

435/068100, 530/403000

Abstract:

Methods for chemical ligation and synthesis of peptides and polypeptides including membrane polypeptides and hydrophobic peptides and polypeptides or membrane polypeptide domains in a multiphase solvent mixture comprising at least two component solvents; compositions produced using these methods and assays performed using these compositions.

US Patent:

20070005258, Jan 4, 2007

Filed:

Jun 7, 2005

Appl. No.:

11/146417

Inventors:

Frank Guarnieri - Brooklyn NY, US
Frank Hollinger - Wayne PA, US
Stephan Brunner - Preverenges, CH
William Chiang - Pennington NJ, US
Matthew Clark - Wayne PA, US
George Talbot - Philadelphia PA, US
Jason Ferrara - Yardley PA, US

International Classification:

G06F 19/00

US Classification:

702019000

Abstract:

Methods and systems of analyzing positions and orientations of molecular fragments to generate macromolecular binding ligands, including analyzing the positions and orientations of molecular fragments in relation to other molecular fragments to bond the molecular fragments to form ligands.

US Patent:

20110294959, Dec 1, 2011

Filed:

May 26, 2011

Appl. No.:

13/116427

Inventors:

Jiangfeng Fei - Sleepy Hollow NY, US
William Chiang - Pennington NJ, US
Frank Kerrigan - Wadebridge, GB
Stuart Green - Camelford, GB
Craig Robson - Camelford, GB
Howard Easterfield - Bude, GB

Assignee:

BAYER HEALTHCARE LLC - Tarrytown NY

International Classification:

C08F 8/36
C08F 34/00
C08G 75/24
C08F 22/06

US Classification:

5253267, 5253275, 528377, 525349

Abstract:

A non-leaching mediator may include a polymer having a polymeric backbone, and a plurality of phenothiazine groups bonded to the polymeric backbone. The plurality of phenothiazine groups may include at least one of a phenothiazine group having the general formula (IV):and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded, and a phenothiazine group having the general formula (V):and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded.

US Patent:

59851198, Nov 16, 1999

Filed:

May 10, 1996

Appl. No.:

8/645966

Inventors:

Peter John Zanzucchi - Lawrenceville NJ
Charlotte Anna Burton - Brick NJ
Sterling Edward McBride - Lawrenceville NJ
Satyam Choudary Cherukuri - Cranbury NJ
William Chiang - Monmouth Junction NJ
Aaron W. Levine - Mercer NJ
Richard Morgan Moroney - Princeton NJ

Assignee:

Sarnoff Corporation - Princeton NJ

International Classification:

G01N 2726

US Classification:

204450

Abstract:

The invention provides methods of performing a synthetic process in a liquid distribution system having reaction cells, by pumping at least one reagent into a reaction cell.

US Patent:

63261499, Dec 4, 2001

Filed:

Nov 2, 1999

Appl. No.:

9/432745

Inventors:

Zyi Gerald Loewy - Fair Lawn NJ
William Chiang - Monmouth Junction NJ
Hoi Cheong Sun - Dayton NJ
Bryan Lloyd Bentz - Princeton NJ

Assignee:

Sarnoff Corporation - Princeton NJ

International Classification:

C12Q 168
B05D 104
B05D 112
H05C 100

US Classification:

435 6

Abstract:

Provided is a method of fabricating a substrate having on a surface thereof two or more spatially-resolved regions, each with a defined amount or concentration of one of one or more chemical components, the method comprising: associating a chemical component with particles of 1. mu. m to 500. mu. m diameter; electrostatically depositing the particles on the appropriate regions; and if a said spatially-resolved region is to receive a second chemical component, repeating steps (a) and (b) for that chemical component and the appropriate regions.

US Patent:

59618000, Oct 5, 1999

Filed:

May 8, 1997

Appl. No.:

8/848413

Inventors:

Sterling Eduard McBride - Lawrenceville NJ
William Chiang - Monmouth Junction NJ
Paul James Heaney - Skillman NJ
Satyam Choudary Cherukuri - Cranbury NJ

Assignee:

Sarnoff Corporation - Princeton NJ

International Classification:

G01N 2726

US Classification:

204450

Abstract:

Provided is an electrode-based pump having source of a pumped fluid, a conduit channel of capillary dimensions connected via a first end to the pumped fluid source and having an outlet at a second end, a piston channel with a first end that intersects the conduit channel, wherein the piston channel allows for periodic inward and outward movement of a piston plug of liquid, two or more electrodes inserted into the piston channel which define an electrode-based pump, wherein the electrode-based pump can be operated to move the piston plug of liquid inward and outward.

US Patent:

48883964, Dec 19, 1989

Filed:

Jun 8, 1988

Appl. No.:

7/203835

Inventors:

Herbert K. Reimschuessel - Morristown NJ
William G. Chiang - Fayetteville NY
George J. W. Tichenor - Fayetteville NY

Assignee:

Polypure, Inc. - Solvay NY

International Classification:

C08F 830

US Classification:

525379

Abstract:

Novel cationic polymers are provided by reaction of high molecular weight polymers and copolymers of acrylamide with an alkyl epoxide compound such as glycidyldialkylamine or glycidyltrialkylammonium salt to form polymer chain units containing e. g. pendant (N-2-hydroxypropyl) dialkylamine groups of their trialkylammonium salts. Processes for making the graft copolymers are provided in which the reaction is carried out while maintaining the reaction mixture in gel form by swelling the starting solid polymer with a solvent mixture. The reaction may be carried out in a homogeneous reaction environment or in a heterogeneous reaction environment by dispersing the starting solid polymer in an inert liquid that is a non-solvent for both the polymer and the salt. The polymeric products of the reaction may be hardened with a suitable liquid, such as isopropanol, to a solid particulate material.